The Abstracts of Papers in the Journal of the Chinese Rare Earth Society（inChinese）

ＴｈｅＡｂｓｔｒａｃｔｓｏｆＰａｐｅｒｓｉｎｔｈｅＪｏｕｒｎａｌｏｆｔｈｅＣｈｉｎｅｓｅＲａｒｅＥａｒｔｈＳｏｃｉｅｔｙ（ｉｎＣｈｉｎｅｓｅ）￥／／ＴｈｅＥｆｆｅｃｔｏｆＡｄｄｉｎｇＴｒａｃｅＧａｄｏｌｉｎｉｕｍｔｏｔｈｅＡｇ－ＣｕＡｌｌｏｙｓｏｎＲ...     

The Abstracts of Papers in the Journal of the Chinese Rare Earth Society （inChinese）

ＴｈｅＡｂｓｔｒａｃｔｓｏｆＰａｐｅｒｓｉｎｔｈｅＪｏｕｒｎａｌｏｆｔｈｅＣｈｉｎｅｓｅＲａｒｅＥａｒｔｈＳｏｃｉｅｔｙ（ｉｎＣｈｉｎｅｓｅ）ＥｆｆｅｃｔｓｏｆＲａｒｅＥａｒｔｈＮｉｔｒａｔｅｓｏｎＳｏｍｅＩｍｍｕｎｅＦｕｎｃｔｉｏｎｓｉｎＭＩＣＥＬ...     

The Abstracts of Papers in the Journal of the Chinese Rare Earth Society （in Chinese）

ＴｈｅＡｂｓｔｒａｃｔｓｏｆＰａｐｅｒｓｉｎｔｈｅＪｏｕｒｎａｌｏｆｔｈｅＣｈｉｎｅｓｅＲａｒｅＥａｒｔｈ　Ｓｏｃｉｅｔｙ（ｉｎＣｈｉｎｅｓｅ）ＴｈｅＡｂｓｔｒａｃｔｓｏｆＰａｐｅｒｓｉｎｔｈｅＪｏｕｒｎａｌｏｆｔｈｅＣｈｉｎｅｓｅＲａｒｅＥａｒｔｈ...     

The Abstracts of Papers in the Journal of the Chinese Rare Earth Society（inChinese）

ＴｈｅＡｂｓｔｒａｃｔｓｏｆＰａｐｅｒｓｉｎｔｈｅＪｏｕｒｎａｌｏｆｔｈｅＣｈｉｎｅｓｅＲａｒｅＥａｒｔｈＳｏｃｉｅｔｙ（ｉｎＣｈｉｎｅｓｅ）ＴｈｅＡｂｓｔｒａｃｔｓｏｆＰａｐｅｒｓｉｎｔｈｅＪｏｕｒｎａｌｏｆｔｈｅＣｈｉｎｅｓｅＲａｒｅＥａｒｔｈＳ...     

Abstracts of Papers in Journal of the Chinese Rare Earth Society

ＳｔｕｄｙｏｎＲｅｃｏｖｅｒｙＴｅｃｈｎｉｃｓｆｏｒＲａｒｅＥａｒｔｈｏｆＭＨ ＮｉＢａｔｔｅｒｙＮｅｇａｔｉｖｅＥｌｅｃｔｒｏｄｅＸｕＬｉｙａｎｇ ,ＣｈｅｎＺｈｉｃｈｕａｎ (ＳｈｅｎｚｈｅｎＨａｚａｒｄｏｕｓＷａｓｔｅＴｒｅａｔｍｅｎｔＳｔａｔｉｏｎ ,Ｓｈｅｎｚｈｅｎ 51 0 0 49,Ｃｈｉｎａ)Ａｂｓｔｒａｃｔ :Ｅｎｖｉｒｏｎｍｅｎｔａｌｐｒｏｔｅｃｔｉｏｎａｎｄａｂｓｅｎｃｅｏｆｒｅｓｏｕｒｃｅｐｒｏｖｏｋｅｐｅｏｐｌｅｔｏｐａｙａｔｔｅｎｔｉｏｎｔｏｔｈｅｒｅｕｓｅｏｆｕｓｅｆｕｌｍｅｔａｌｓｉ…     

Effects of Alloying Elements on Microstructure and Magnetic Anisotropy of the HDDR Powder ofNd-Fe-B Alloy

ＥｆｅｃｔｓｏｆＡｌｏｙｉｎｇＥｌｅｍｅｎｔｓｏｎＭｉｃｒｏｓｔｒｕｃｔｕｒｅａｎｄＭａｇｎｅｔｉｃＡｎｉｓｏｔｒｏｐｙｏｆｔｈｅＨＤＤＲＰｏｗｄｅｒｏｆＮｄＦｅＢＡｌｏｙＧａｏＪｉａｎｒｏｎｇ（高建荣），ＳｏｎｇＸｉａｏｐｉｎｇ（宋晓平），Ｗａ...     

Mechanism of RE on the Electrochemical Properties of Multicomponent Hydrogen Storage Alloys of RENi~5 Type

ＭｅｃｈａｎｉｓｍｏｆＲＥｏｎｔｈｅＥｌｅｃｔｒｏｃｈｅｍｉｃａｌＰｒｏｐｅｒｔｉｅｓｏｆＭｕｌｔｉｃｏｍｐｏｎｅｎｔＨｙｄｒｏｇｅｎＳｔｏｒａｇｅＡｌｏｙｓｏｆＲＥＮｉ５ＴｙｐｅＪｉａｎｇＪｉａｎｊｕｎ（江建军）（ＨｕａｚｈｏｎｇＵｎｉｖｅｒｓｉ...     

Study of the Coarse Blocky Compounds in the As－cast 7075 Aluminium Alloys Containing Rare Earth Elements

ＳｔｕｄｙｏｆｔｈｅＣｏａｒｓｅＢｌｏｃｋｙＣｏｍｐｏｕｎｄｓｉｎｔｈｅＡｓ－ｃａｓｔ７０７５ＡｌｕｍｉｎｉｕｍＡｌｌｏｙｓＣｏｎｔａｉｎｉｎｇＲａｒｅＥａｒｔｈＥｌｅｍｅｎｔｓＰａｎＦｕｓｈｅｎｇ；ＺｈｏｕＳｈｏｕｚｅ；ＤｉｎｇＰｅｉｄａｏ；（Ｃｈ...     

The Abstracts of Papers in the Journal of the Chinese Rare Earth Society（inChinese）

ＴｈｅＡｂｓｔｒａｃｔｓｏｆＰａｐｅｒｓｉｎｔｈｅＪｏｕｒｎａｌｏｆｔｈｅＣｈｉｎｅｓｅＲａｒｅＥａｒｔｈＳｏｃｉｅｔｙ（ｉｎＣｈｉｎｅｓｅ）ＣｒｖｓｔａｌＳｔｒｕｃｔｔｕｒｅａｎｄＣｈａｒａｃｔｅｒｉｚａｔｉｏｎｏｆＧｌｕｔａｍａｔｃＣｏｍＰｌｅｘ...     

The Abstracts of Papers in the Journal of the Chinese Rare Earth Society（in Chinese）

ＴｈｅＡｂｓｔｒａｃｔｓｏｆＰａｐｅｒｓｉｎｔｈｅＪｏｕｒｎａｌｏｆｔｈｅＣｈｉｎｅｓｅＲａｒｅＥａｒｔｈＳｏｃｉｅｔｙ（ｉｎＣｈｉｎｅｓｅ）Ｓｙｎｔｈｅｓｉｓ，ＣｈａｒａｃｔｅｒｉｚａｔｉｏｎａｎｄＳｔｒｕｃｔｕｒｅｏｆＴｒｉｂｕｔｙｌａｍｍｏｎｉ...     

Antiandrogen treatment of aggressivity in men suffering from dementia

The effect of Shengmaisan (SMS) on 62 acute viral myocarditis patients and its peroxidation damage was studied. The results revealed that the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in blood were decreased and the content of malondialdehyde (MDA) in plasma was increased in acute viral myocarditis patients in comparison with the healthy controls (P < 0.001). 62 acute viral myocarditis patients were divided into two groups: SMS group and placebo group. After treatment, both SOD and GSH-Px activities were increased and the level of MDA decreased (P < 0.001) in SMS group, while those in placebo group were not changed (P < 0.05). The results suggested that the myocardial damage of viral myocarditis is closely related with lipid peroxidation SMS acts as an effective free radical scavenger and anti-lipid peroxidation drug. SMS could prevent the damage of myocardia and might be taken as one of the effective therapeutic methods in treatment of acute viral myocarditis.     

Impaired antioxidant defence in guinea pig heart tissues treated with halothane

PURPOSE: To investigate the effects of halothane and halothane plus vitamin E treatment on myocardial free radical metabolism in guinea pigs. METHODS: Four groups of seven animals were studied: control, halothane, halothane plus vitamin E and vitamin E groups. In the halothane group, halothane 1.5% in oxygen was given for 90 min over three days. In the halothane plus vitamin E group, 300 mg.kg-1.day-1 vitamin E im was started three days before the first halothane treatment and continued for three days. Following sacrifice, the hearts were assayed for superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) and malondialdehyde (MDA) level was determined. Electron spin resonance (ESR) analysis and electron microscopy (EM) were also performed. RESULTS: In the halothane group, SOD activities and MDA concentrations were increased compared with control and GSH-Px and CAT activities were decreased. In the halothane plus vitamin E group, there were no differences in enzyme activity compared with halothane alone but the MDA level was decreased. In the vitamin E group, enzyme activities were increased compared with control. Mainly the CF3CHCl radical was identified by ESR analysis in heart tissues exposed to halothane and the concentration of this radical was reduced by vitamin E. Electron microscopy showed cytoplasmic vacuolisation and dilation in sarcoplasmic reticulum in the heart tissues exposed to halothane: both were prevented by vitamin E. CONCLUSION: Although halothane causes impairment in enzymatic antioxidant defence potential, due to lowered GSH-Px and CAT activity, and accelerates peroxidative reactions in the tissues affected, no subcellular damage occurred. Vitamin E may protect tissues against free radical attack by scavenging toxic free radicals formed in heart tissue during halothane anaesthesia.     

Genotype effects on the antioxidant enzymes activity and mRNA expression in liver and kidney tissues of autoimmune-prone MRL/MpJ-lpr/lpr mice

Congeneic pairs of MRL/lpr and MRL/++ (+/+) mice differ in incidence of autoantibodies, lymphoproliferative disease and survival, characteristics that are linked to immunological abnormalities. MRL/lpr mice have a significantly shorter life span compared to +/+ mice. Because a weak antioxidant defense and an increased generation of free radicals are generally implicated in the severity of many autoimmune disease, the present study was undertaken to compare the influence of genotype on lipid composition, lipid peroxidation and expression of mRNA, and activity of antioxidant enzymes such as catalase (CAT), glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) in the livers and kidneys of these mice. The expression of SOD, GSH-Px and CAT mRNAs was significantly higher (P < 0.05) in the livers of +/+ mice, while in the kidneys only SOD expression was found significantly higher in +/+ mice when compared to MRL/lpr mice. Further, the activity of cytosolic SOD and GSH-Px was also found significantly higher (P < 0.001) in the livers of +/+ mice. Both livers and kidneys of MRL/lpr mice exhibited significantly higher levels of arachidonic acid (20:4(n-6)), significantly higher generation of thiobarbituric acid reactive substances (TBARS) and higher estimated peroxidation index than the +/+ mice. In addition, the MRL/lpr mice had higher levels of serum anti-cardiolipin antibodies. In summary, the results from the present study indicate that besides several immune-related abnormalities, the MRL/lpr mice may exhibit their inability to cope with oxidative stress due to a poor antioxidant defense system.(ABSTRACT TRUNCATED AT 250 WORDS)     

Lipid peroxidation and antioxidant status in the liver, erythrocytes, and serum of rats after methanol intoxication

Lipid peroxidation products measured as a malondialdehyde and activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), glutathione reductase (GSSG-R), and concentrations of ascorbic acid, alpha-tocopherol, and glutathione (GSH) were measured in the liver, erythrocytes, and serum of rats 6, 14, and 24 h and 2, 5, and 7 d after treatment with 3 g methanol/kg. GSH-Px and GSSG-R activities, GSH level, and ascorbate concentration in the liver, erythrocytes, and blood serum were significantly decreased. In addition, SOD and alpha-tocopherol in erythrocytes were diminished, while malondialdehyde (MDA) in liver, erythrocytes, and serum were elevated. Further, erythrocyte counts, hemoglobin levels, hematocrit, and mean corpuscular volume (MCV) were reduced. These results indicate that methanol intoxication in rats leads to an increase in the lipid peroxidation and impairment in the antioxidant mechanisms in liver, erythrocytes, and blood serum.     

Oxidative stress in the human brain after subarachnoid hemorrhage

OBJECT: The aim of this study was to verify the patterns of antioxidant enzymatic activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in the human brain after subarachnoid hemorrhage (SAH) to verify whether an "oxidative stress situation" characterizes the brain response to subarachnoid bleeding. METHODS: Forty samples of gyrus rectus or temporal operculum that were obtained during a surgical approach to anterior circulation aneurysms were used for this study. The activity of total SOD, GSH-Px, and the SOD/GSH/Px ratio (which expresses the balance between the production of hydrogen peroxides by dismutation of superoxide radicals and the scavenging potential) were calculated in each case. Twelve samples were obtained from patients who underwent surgery for unruptured aneurysms (control group); 13 samples were obtained during surgical procedures performed within 72 hours of SAH; and 15 samples were obtained during delayed surgical procedures (> 10 days post-SAH). Ten patients presented with clinical deterioration caused by arterial vasospasm. In both SAH groups, the mean total SOD activity was significantly higher than in the control group (p=0.029). The mean activity of GSH-Px did not differ significantly between the SAH and control groups (p=0.731). There was a significant increase in the SOD/GSH-Px ratio in both SAH groups, as compared with controls (p < 0.05). There was a significant correlation between the enzymatic activity and the clinical severity of the hemorrhage, with findings of lower values of SOD and, mainly, of the SOD/GSH-Px ratio in the poor-grade patients. The SOD/GSH-Px ratio was 2.14+/-0.44 in patients who presented with clinical vasospasm and 1.24+/-0.2 in cases without vasospasm. CONCLUSIONS: The results of this study show an imbalance of the antioxidant enzymatic activities in the human brain after SAH. which is linked to the severity of the initial bleeding and possibly modified by the development of arterial vasospasm.     

Effects of Lanthanum on Root Growth and Senescence of GF43 （ Prunus domestica ） Plantlet in Vitro

The effect and the action mechanism of lanthanum on GF43 plantlet in vitro were studied. The results of experiments show that root growth rate and dry weight of GF43 by LaCI3 treatments increase. The activities of antioxidant enzymes in root system such as superoxide dismutase (SOD), catalase (CAT) and peroxidase (POD) apparently enhance. Moreover O^-2 and malond ialdehyde (MDA) contents and cell membrane permeability of GF43 are decreased by LaC13. The relatively stable membrane structure of cell could also be maintained and the root ageing of GF43 plantlet in vitro delays.     

低剂量辐射对环磷酰胺化疗毒性作用的影响

Objective:The aim of the study was to investigate the effects as well as the possible mechanisms of low dose y-ray pre-irradiation on hepatic damage, DNA damage of peripheral lymphocytes and genetic material damage caused by high dosage of cyclophosphamide (CTX). Methods: Kunming strain male mice were randomly divided into five groups:control group, sham-irradiated group, low dose irradiation group (LDR group), cyclophosphamide chemotherapy group (CTX group) and low close irradiation combined with chemotherapy group (LDR + CTX group). Having being raised for one week,all the mice were implanted subcutaneously with S180 cells in the left inguen (control group excluded). On days 8 and 11,mice of LDR and LDR + CTX groups were given 75 mGy whole-body y-irradiation, 30 h later mice of CTX and LDR + CTX groups were injected I.p. 3.0 mg cyclophosphamide. All the mice were sacrificed on day 13. DNA damage of the peripheral lymphocytes was analyzed using single cell gel electrophoresis (SCGE); ALT activity, total protein (TP) and albumin (ALB)of the plasma were analyzed using automatic biochemistry analyzer; MDA content, SOD and GSH-PX activity of the hepatic homogenate were analyzed using chromometry; genetic material damage was analyzed using micronucleus frequency (MNF)of polychromatoerythrocytes (PCE) in bone marrow. Results: 1. Differences of MDA contents, SOD and GSH-PX activity of hepatic homogenate between 5 groups had notable statistical significance (P < 0.01); in control group MDA content was the lowest, SOD and GSH-PX activity were the highest, while in CTX group MDA content was the highest, SOD and GSH-PX activity were the lowest; compared with CTX group MDA content decreased significantly (P < 0.01) and SOD and GSH-PX activity increased significantly (P <0.05) in LDR + CTX group. 2. Differences of ALT activity of plasma between 5 groups had no statistical significance (F = 1.262, P > 0.05). Differences of TP and ALB of plasma between 5 groups had statistical sig-nificance (F = 12.879 and 6.336 respectively, P < 0.01); TP and ALB in control group were higher than those of other groups and compared with sham-irradiated group, TP and ALB in LDR group elevated significantly (P < 0.05). 3. Differences of DNA damage of peripheral lymphocytes had notable statistical significance (F = 6.383, P < 0.01); DNA damage in control group was the lightest, while DNA damage in CTX group was the severest; compared with CTX group, DNA damage in LDR + CTX group was much lighter (P < 0.05). 4. MNF of PCE between 5 groups had remarkable significance (F = 179.652, P < 0.01);compared with control group and sham-irradiated group, MNF in CTX group increased significantly (P < 0.01); compared with CTX group, MNF in LDR + CTX group had a tendency of decline, which had no statistical significance (P > 0.05). Conclusion:1. CTX can damage the hepatic tissue through oxidative stress; 75 mGy y-irradiation before CTX chemotherapy can induce activities of anti-oxidative enzymes, promote elimination of free radicals, so as to alleviate the damaging effects of oxidative stress to hepatic tissue caused by high-close chemotherapy. 2. A 75 mGy y-irradiation before CTX chemotherapy has no obvious effect on ALT activity of plasma, but may have protective effect on the protein synthesis function of liver. 3. High-close CTX chemotherapy can cause DNA damage of peripheral lymphocytes; 75 mGy y-irradiation before chemotherapy may have certain protective effect on DNA damage. 4. CTX has potent mutagenic effect, can cause significant increase of MNF of PCE;75 mGy y-ray pre-irradiation did not show obvious protection against genetic toxicity of high-dose CTX chemotherapy.     

Antioxidative Capacity of Irbesartan

The author investigated the antioxidant effect of irbesartan[2-butyl-3-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1,3-diazaspiro[4.4]non-1-en-4-one],an angiotensin receptor biocker(ARB),on the oxidation of erythrocytes induced by 2,2-[azobis(2-amidinopropane)hydrochloride](AAPH)and H2O2.The value of half concentration(IC50)of irbesartan to scavenge radicals was measured by reacting it with 2,2-[azinobis(3-ethylbenzothiazoline-6-sulfonate)radical cation](ABTS+).Activities of the catalase(CAT),superoxide dismutase(SOD),glutathione peroxidase(GSH-Px)and the content of malondialdehyde(MDA)in liver tissue and blood serum of normal-rats were measured by means of spectrophotometry to study the antioxidation function of irbesartan.Results of experiments show that irbesartan can scavenge ABTS+ and superoxide radicals effectively as well as inhibit AAPH-,H2O2-induced hemolysis of erythrocytes,Irbesartan can also increase the activities of GSH-Px,SOD,CAT and decrease the content of MDA of normal rats.So irbesartan is a good antioxidant.     

Glutathione peroxidase in amyotrophic lateral sclerosis: the effects of selenium supplementation

The activity of glutathione peroxidase (GSH-Px) as well as the activities of other antioxidative enzymes: CuZn superoxide dismutase (CuZn SOD), catalase (CAT), glutathione reductase (GR) in erythrocytes, as well as the activity of plasma glutathione transferase (GST), and the plasma content of vitamins E and C were evaluated in 35 sporadic amyotrophic lateral sclerosis (sALS) patients. The results revealed significantly decreased activity of both GSH-Px and CuZn SOD in sALS patients compared with the control. These data showed that a disturbed oxidative/antioxidative balance in sALS patients exists not only in motoneurons but also in the blood. The effect of exogenously administered selenium (Se), antioxidants, amino acids, a Ca2+ channel blocker such as nimodipine, and their combination in Alsamin was evaluated by screening parameter levels after 9 weeks of treatment. Only the use of all components together enhanced the activity of GSH-Px and the amount of vitamin E in sALS patients. Judging by the results of clinical trials, this treatment slowed the course of the disease.     

Effect of NdCl_3 on the Injury of Membrane and ABA Content under Osmotic Stress

ＥｆｆｅｃｔｏｆＮｄＣｌ_３ｏｎｔｈｅＩｎｊｕｒｙｏｆＭｅｍｂｒａｎｅａｎｄＡＢＡＣｏｎｔｅｎｔｕｎｄｅｒＯｓｍｏｔｉｃＳｔｒｅｓｓ￥ＡｎＪｉａｎｐｉｎｇ（安建平）（ＢｉｏｌｏｇｙＤｅｐａｒｔｍｅｎｔ，ＴｉａｎｓｈｕｉＮｏｒｍａｌＣｏｌｌｅｇｅ，Ｔｉ?..