苏州市某社区产后抑郁流行病学调查及相关危险因素

目的调查苏州市某社区产后抑郁的检出率及相关危险因素,为产后抑郁的防治提供参考。方法选取苏州市某社区88例产妇,采用爱丁堡产后抑郁量表(EPDS)评定其产后抑郁情况,采用艾森克人格问卷(EPQ)和社会支持评定量表(SSRS)评定产妇的个性特征及社会支持情况。以EPDS评分9分为界将产妇分为产后抑郁组和正常组,分析影响产后抑郁的相关因素。结果苏州市某社区产后抑郁检出率为21.6%;产后抑郁组EPQ神经质(N)维度评分高于正常组,差异有统计学意义[(88.45±8.07)分vs.(37.16±8.22)分,t=2.625,P0.05]。产后抑郁组与正常组SSRS总评分与各维度评分比较差异均无统计学意义(t=-1.411~-0.590,P均0.05)。产后抑郁组SSRS客观支持及主观支持评分与EPDS评分均呈负相关(r=-0.471、-0.459,P均0.05)。结论苏州市某社区产后抑郁的检出率较高,产妇的神经质人格特质与产后抑郁有关。     

睡眠障碍与产后抑郁症之间的关联

目的 评估女性产后睡眠障碍和产后抑郁症的发生率，并探讨产后睡眠障碍对产后抑郁 症发生的影响。方法 采用横断面的研究设计，对2017 年1 月至2018 年12 月于解放军空军军医大学西 京医院进行分娩后复查的252 名产妇进行基础资料调查。采用匹兹堡睡眠质量量表（PSQI）和爱丁堡产 后抑郁量表（EPDS）评估睡眠质量和产后抑郁症状。EPDS ＞ 9.5 分定义产后抑郁症，根据产妇产后是否 发生抑郁症，将252 名产妇分为产后抑郁组与非抑郁组。结果 本研究中产妇睡眠障碍和产后抑郁症 的发生率分别为36.1%（91/252）和25.8%（65/252）。单因素分析中，产后抑郁组产妇PSQI 总分显著高于 非抑郁组［（8.43±2.37）分比（5.76±1.84）分；t=9.293，P＜ 0.01］；除睡眠时间分量表外，产后抑郁组PSQI 各分量表得分均高于非抑郁组产妇（均P＜ 0.01）；产后抑郁组产妇睡眠障碍（PSQI ＞ 7 分）发生率明显高 于非抑郁组产妇［52.3%（34/65）比30.5%（57/187）；χ2=9.960，P=0.002］。多因素Logistic 回归分析结果显 示，在调整了社会人口统计学变量、围产期变量和妊娠期疾病变量后，产后睡眠质量和产后抑郁症之间 的关联仍然显著（OR=2.35，95%CI：1.32～4.21）。结论 产后睡眠障碍与产后抑郁症存在正向关联，对 于存在产后睡眠障碍的产妇，应尽早提供干预措施，以减少抑郁症的发生风险。     

产后抑郁症患者心理评估及其危险因素

目的评估产后抑郁症患者的心理状况,分析产后抑郁症的危险因素。方法选取我院从2017年1月～2018年12月收治的产后抑郁症患者320例作为观察组,同时选取同期在我院进行分娩的无产后抑郁症产妇100例作为对照组。采用自制调查问卷了解两组产妇基本情况,采用爱丁堡产后抑郁量表(EPDS)及抑郁自评量表(SDS)对两组产妇抑郁情绪进行对比,筛选影响产后抑郁症的相关因素,行logistic回归分析产后抑郁症的危险因素。结果观察组EPDS评分及SDS评分显著高于对照组(P0.05);观察组在年龄、产妇文化程度、家庭关系、家庭经济收入、居住条件、产前定期产检情况、孕期焦虑或抑郁情绪、产前并发症、分娩方式、新生儿健康状况与对照组存在明显差异(P0.05);logistic回归分析示年龄、文化程度、家庭经济收入、居住条件、产前定期产检、孕期抑郁或焦虑情绪、产前并发症、分娩方式、新生儿健康状况是产后抑郁症的危险因素。结论产后抑郁症的出现受产妇心理、生理、家庭、社会以及环境等多种因素的影响。     

社会支持和应对方式与脑卒中后抑郁的关系

目的：探讨社会支持和应对方式与脑卒中后抑郁（PSD）的关系.方法：30例PSD患者为PSD组,42例脑卒中后无抑郁患者为对照组,以医学应对问卷（MCMQ）、社会支持评定量表（SSRS）和Barthel指数（BI）为评定工具,对两组患者分别进行评定.结果：PSD组MCMQ的面对量表分显著低于对照组（P＜0.05）,而PSD组屈服量表分显著高于对照组（P＜0.01）.PSD组的SSRS评分显著低于对照组（P＜0.01）.两组BI评分差异无显著性（P＞0.05）.结论：有针对性的心理教育性干预并加强社会支持可能对防治PSD起重要作用.     

农村精神分裂症患者的社会支持状况分析

目的：了解农村精神分裂症患者社会支持状况及其相关因素。方法：对治愈出院6个月复诊的114例农村精神分裂症患者进行社会支持评定量表(SSRS)测评，以50名正常农民为对照组。结果：患者组SSRS总分及3个维度分均显著低于正常对照组；女性患者SSRS总分及主观支持分显著高于男性患者；女性患者已婚比率高于男性患者；多元线性回归分析发现社会支持与婚姻状况及病程有关。结论：农村精神分裂症缓解期患者社会支持比正常人少，已婚及病程短者社会支持水平较高。     

乳腺癌患者的社会支持及其相关因素分析

目的初步分析乳腺癌患者的社会支持及其相关因素。方法采用社会支持评定量表（SSRS）对33例乳腺癌患者与29例健康女性进行问卷测评分析。结果乳腺癌组的主观支持分低于对照组，有显著差异（P〈0．05）；乳腺癌组已婚者主观支持分值低于对照组，且有显著性差异（P〈0．05）；乳腺癌组大学以上文化程度者的客观支持分、主观支持分及总社会支持分均低于对照组，且有显著差异（P〈0．05）。结论乳腺癌患者的主观支持较差，尤以已婚乳腺癌患者明显；大学以上文化程度的乳腺癌患者主、客观社会支持均差。     

产后抑郁症患者与人格、社会支持的相关研究

目的 探讨产后抑郁症与人格、社会支持的关系.方法 共计1 292例初产妇,诊断为产后抑郁症的232例为研究组,而无抑郁症状的1060例为对照组,问卷评定采用爱丁堡产后抑郁量表、艾森克个性问卷及社会支持评定量表.结果 产后抑郁症的检出率为17.96%.研究组的E维度、L维度因子分评分显著低于对照组(P<0.05),而研究组的N维度因子分评分显著高于对照组(P<0.05).研究组的客观支持、主观支持、利用度因子评分显著低于对照组(P<0.05).结论 产后抑郁症与患者的人格特征及社会支持等因素有关.     

难治性抑郁症患者心理社会因素分析

目的探讨心理社会危险因素在难治性抑郁症发病中的相关机制。方法难治性抑郁症患者、非难治性抑郁症患者和正常对照者各30例。被试者完成一般情况问卷、艾森克个性问卷（EPQ）、生活事件量表（LES）、社会支持评定量表（SSRS）,汉密尔顿抑郁量表（HAMD）、汉密尔顿焦虑量表（HAMA）评定。采用t检验、χ2检验、Pearson相关性分析、多元逐步回归分析方法,应用SPSS10.0软件完成数据统计。结果①难治性抑郁症组EPQ内外向因子分显著低于非难治性抑郁症组和正常对照组,神经质因子分显著高于非难治性抑郁症组和正常对照组。负性事件总分、社交及其他问题因子分显著高于非难治性抑郁症组和正常对照组,社会支持总分、客观支持分显著低于非难治性抑郁症组和正常对照组。②HAMD总分与负性事件总分、EPQ精神质因子分、神经质因子分呈正相关,与社会支持总分、主观支持因子分、客观支持因子分、支持利用度因子分呈负相关,HAMA总分与EPQ神经质因子、负性事件总分呈正相关,与EPQ内外向因子分、社会支持总分、支持利用度因子分呈负相关。③多因素分析结果：负性事件和低社会支持是抑郁的危险因素,EPQ神经质因子是焦虑的危险因素。结论性格内向,情绪不稳定,体验较多的负性生活事件,社会支持低下是难治性抑郁症的危险因素。应激、社会支持影响难治性抑郁症的严重程度和预后。     

精神分裂症患者社会支持程度与血清神经功能指标水平及阴性 症状、抑郁症状的相关性

目的 探讨精神分裂症患者社会支持程度与血清神经功能指标水平、阴性症状及抑郁症 状的相关性。方法 2014年9月至2018年6月攀枝花市第三人民医院收治的首发精神分裂症患者92例， 参照随机数表法将入组患者分为对照组、研究组各46 例。对照组患者常规服用抗精神病药物，研究组 患者接受社会支持干预＋抗精神病药物治疗，持续1 个月后进行效果评估。对比两组患者干预前后社 会支持评定量表（SSRS）评分，同时研究组根据干预后SSRS 评分中位数进一步被分为高SSRS 评分组、低 SSRS 评分组各23 例。对比对照组、研究组，研究组不同SSRS 评分组间血清神经递质［多巴胺（DA）、γ- 氨基丁酸（GABA）、乙酰胆碱（Ach）］、神经营养因子［脑源性神经营养因子（BDNF）、神经生长因子（NGF）］ 的含量，阴性症状量表（SANS）、卡尔加里精神分裂症抑郁量表（CDSS）评分值的差异。结果 干预后，研 究组的SSRS 评分值高于对照组；DA、GABA 的含量高于对照组，Ach 的含量低于对照组；BDNF、NGF的 含量高于对照组；SANS、CDSS 评分值低于对照组（P＜ 0.05）。高SSRS 评分组的上述指标变化幅度均大 于低SSRS 评分组（P ＜ 0.05）。结论 社会支持干预可有效优化精神分裂症患者的病情，社会支持程度 可能是影响患者病情的重要因素之一。     

心理社会因素对产后抑郁症发生的相关性分析

目的 探讨产后抑郁症发生的心理社会因素。方法 对住我院被诊断为产后抑郁症的45例病人与45例非产后抑郁症和45例正常产妇作对照研究。结果 产后抑郁症在症状学方面与非产后抑郁症差别不大，但它有较多的负性刺激和家庭问题，受到的客观支持也少。结论 产后抑郁症的发生与生活事件等心理社会因素有关。     

产后抑郁症患者的心理社会因素分析

目的研究产后抑郁症患者的人格特征、生活事件及社会支持影响因素。方法对93例产后抑郁症患者及135名正常产妇分别应用艾森克人格问卷、生活事件量表及社会支持评定量表进行评估。结果与正常产妇相比较,产后抑郁症在人格方面具有内倾及神经质倾向,且常经历较多的负性生活事件;产后抑郁症组的社会支持总分及其各分量表得分均显著低于正常组。结论产后抑郁症的发生与人格、生活事件及社会支持等心理社会因素有关。     

Postpartum depression symptoms in newcomers.

OBJECTIVES: To determine if postpartum depression (PPD) symptoms are more common in newcomer women than in Canadian-born women. METHODS: Refugee, nonrefugee immigrant, asylum-seeking, and Canadian-born new mothers were administered questionnaires for depression, social support, interpersonal violence, and demographic information. We created a PPD variable based on a score of > or = 10 on the Edinburgh Postnatal Depression Scale (EPDS) and performed a logistic regression analysis for PPD. RESULTS: Immigrants (35.1%), asylum seekers (31.1%), and refugees (25.7%) were significantly more likely than Canadian-born (8.1%) women to score > or = 10 (P = 0.008) on the EPDS, with the regression model showing an increased risk (odds ratio) for refugee (4.80), immigrant (4.58), and asylum-seeking (3.06) women. Women with less prenatal care were also more likely to have an EPDS of > or = 10 (P = 0.03). Newcomer women with EPDS scores of > or = 10 had lower social support scores than Canadian-born women (P < 0.0001). CONCLUSIONS: Newcomer mothers have an increased risk for PPD symptoms. Social support interventions should be tested for their ability to prevent or alleviate this risk.     

A study of the Edinburgh Postnatal Depression Scale (EPDS) on 859 mothers: detection of mothers at risk for postpartum depression

The postpartum is a high-risk period for the occurrence of anxious and depressive episodes. Indeed, during the first few days after delivery, mothers can present postpartum blues symptomatology: fatigue, anxiety, disordered sleeping and a changing mood. Postpartum depression is characterised by a changing mood, anxiety, irritability, depression, panic and obsessional phenomena. It occurs in approximately 10 to 20% mothers. The exact prevalence depending on the criteria used for detection. The first symptoms usually appear between the fourth and sixth week postpartum. However, postpartum depression can start from the moment of birth, or may result from depression evolving continuously since pregnancy. We can add that the intensity of postpartum blues is a risk factor that can perturb maternal development. So it is important for health professionals to dispose of predictive tools. This study is a validation of the French version of the EPDS. The aims of the study were to evaluate the postpartum depression predictive value at 3 days postpartum and to determine a cut-off score for major depression. Subjects participating in this study were met in 3 obstetrical clinics in, or in the vicinity of, Toulouse. Mothers with psychological problems, under treatment for psychological problems or mothers whose babies present serious health problems were excluded from the study. The EPDS was presented to 859 mothers (mean age=30.3; SD=4.5) met at one of the clinics at 3 days postpartum (period 1). They had an EPDS mean score of 6.4 (SD=4.6); 258 (30%) mothers had an EPDS score 9. 82.6% of these mothers experienced a natural childbirth and 17.3% a caesarean section; 51.5% gave birth to their first child, 36.2% to their second child and 12.3% to their third or more. All subjects were given a second EPDS with written instructions to complete the scale during the period 4 to 6 weeks postpartum and return it for analysis (period 2). Between the 4 to 6 weeks postpartum period, 722 mothers replied again to the EPDS. 131 mothers had an EPDS score 11 (mean age=30.3; SD=4.8). They had an EPDS mean score of 13.6 (SD=3.3). Mothers with probable depression were interviewed and assessed, using the Mini (Mini Neuropsychiatric Interview, Lecrubier et al. 1997), the SIGH-D (Structured Interview Guide for the Hamilton Depression Scale) and the BDI (Beck Depression Inventory) in order to diagnose a major depressive episode. They had a HDRS mean score of 13.7 (SD=5.1) and a BDI mean score of 13.6 (SD=5). At 3 days postpartum, we observed that 258 mothers (30%) had an EPDS scores 9 and 164 mothers (19%) had an EPDS scores 11. Between 4 and 6 weeks postpartum, we observed 18.1% of postpartum depression (EPDS 11) and 16.8% (EPDS 12) of major postpartum depression. The analysis of the sensitivity and the specificity at 3 days postpartum provides a cut-off score of 9 (Sensibility: 0.88) (Specificity: 0.50) as predictive of postpartum depression, for this cut-off score, the type I error is low (5.8%) but the type II error is more higher (18.9%). The analysis of the sensitivity and the specificity between 4 and 6 weeks postpartum provides a cut-off score of 12 (Sensibility: 0.91) (Sensibility: 0.74) for the detection of major postpartum depression. Factor analysis shows at 3 days postpartum that the internal structure of the scale is composed of two subscales. The first factor F1 "anxiety" accounts 28% of the variance and the second factor F2 "depression" accounts 20% of the variance. Between 4 and 6 weeks postpartum, factor analysis suggests an unidimensional model in the evaluation of postpartum depression which is better than a two factor model. This factor accounts 40% of the variance. The scale has a good predictive value, and we can observe a significant correlation with the EPDS periods 1 and 2 (r=0.56; p<0.05). This result shows that the depressive mothers mood intensity predicts a future depressive risk. Furthermore, correlations between EPDS and BDI (r=0.68; p<0.05) and EPDS and HDRS (r=0.67; p<0.05) show a good convergent validity. The reliability study confirms the good internal consistency of the EPDS, at 3 days postpartum and in the postpartum depression -symptomatology evaluation (Cronbach's Alpha>0.80). In conclusion, this scale demonstrates good validity and is fast and easy use in obstetrical services, allowing early detection of women who risk to develop postpartum depression and, in the first week of postpartum, of mothers who suffer from a major postpartum depression. The use of the EPDS for an early screening of the risk of postnatal depression which is essential considering the consequences that postnatal depression can have on the development of the infant, on the quality of the relationship within the couple and on other social relationships. Mothers at risk for postnatal depression should be controlled and surveyed by the health professionals in obstetrical clinics.     

性激素、催乳素与产后抑郁的相关研究

目的：本研究主要探讨产后雌二醇（Ｅ２）、催乳素（ＰＲＬ）变化和产后抑郁症状间的关系。方法：对３８名产妇在产程开始前和产后第７２小时分别抽取血标本,使用放射免疫法检测产后Ｅ２、Ｐ和ＰＲＬ的数量变化,同时用Ｅｄｉｎｇｂｕｒｇｈ产后抑郁量表（ＥＰＤＳ）、Ｂｅｓｋ抑郁量表（ＢＤＩ）、一般健康问卷（ＧＨＱ）对产妇在产后第３天和产后第４２天进行评定。结果：产后第３天ＥＰＤＳ和ＢＤＩ量表分值显著高于产后第４２天,产后Ｅ２变化与ＥＰＤＳ、ＢＤＩ量表分呈显著负相关,产后Ｐ变化和产后第４２天ＧＨＱ量表分呈显著正相关,ＰＲＬ变化和产后情绪状况无明显关系。结论：产后内分泌激素变化可能是产后抑郁的病因之一。     

Affective (depressive) morbidity in puerperal Nigerian women: validation of the Edinburgh Postnatal Depression Scale

OBJECTIVE: To determine the rate of depression in a group of postpartum Nigerian women and to validate the Edinburgh Postnatal Depression Scale (EPDS) in this group. METHOD: Between April and August 2000, all postpartum women who remained in the maternity ward for up to 7 days, and those who attended the postnatal clinics of Nnamdi Azikiwe University Teaching Hospital were recruited. Translated local language versions of the EPDS and the Zung Self-Rating Depression Scale were used to screen the subjects. A structured interview schedule was adapted from the depression section of the Composite International Diagnostic Interview and affective module of the ICD-10 Symptom Check List to assess screened subjects. RESULTS: The total rejection rate was 23%, with 225 women participating in the study. Twenty-four subjects (10.7%) had depression. At the optimal cut-off score of 9, the EPDS had a sensitivity of 0.75, and specificity of 0.97. CONCLUSION: The EPDS clearly distinguished between depressed and non-depressed postpartum mothers (t = 7.63, P < 0.001, df = 222). Because of its brevity and acceptability, it is recommended that the EPDS be used in routine postnatal screening.     

The validity of the Arabic Edinburgh Postnatal Depression Scale

For the purpose of this study, a consecutive sample of 95 postpartum women were assessed at 1 week postpartum with the (EPDS) and at 8±2 weeks postpartum using the Present State Examination (PSE). A moderate correlation between PSE total score and EPDS score was found (r=0.57). A moderate agreement between EPDS and Catego diagnosis of depression was also found (Kappa=0.52). Using a cut-off score of 12 on EPDS and Catego diagnosis as a criterion variable, the sensitivity and specificity of the scale were 73% and 90%, respectively. However, using a cut-off score of 10, the sensitivity of the scalerose to 91% without much fall in its specificity (84). The internal reliability of the scale was 0.84 ( Cronbach). We conclude that the Arabic version of the EPDS is a reliable and valid screening tool for depression in postpartum women.     

Screening and intervention for depressive mothers of new-born infants]

BACKGROUND AND THE AIM OF THE STUDY: Postnatal depression is a key concept for mother-infant mental health. Evidence of its impact on mother-infant relationship has been increasingly demonstrated in recent years. Therefore optimal intervention is important for women and their babies' mental health. Identifying risk factors of postnatal depression and developing screening system are needed. Study I Hospital-based prospective study--onset and course of Postnatal depression and developing screening system. SAMPLING AND METHOD: One hundred and one consecutive admitted women on maternity ward in our university hospital were invited to the study and 88 mothers participated. Present psychiatric status was assessed by telephone interview at three weeks and three months postnatally, using the Schedule for Affective Disorders and Schizophrenia and diagnosis was made based on Research Diagnostic Criteria. The Maternity Blues Scale and Edinburgh Postnatal Depression Scale (EPDS) were also administered at the 5th day, one and three months postnatally. RESULTS AND DISCUSSION: At 3 weeks, 21 of the 88 mothers (24%) were categorized as having had Maternity blues, and twelve (14%) were diagnosed as depression cases. At 3 months postpartum overall 15 of 88 mothers (17%) were categorized as depression cases. Ten out of total 15 mothers had their onset of depression within the first week. There were no differences in age, parity, educational level, social class compared to non-depressed mothers. The scores of the Blues and the EPDS were always significantly higher in depressed mothers. The Blues scale score was significantly higher in the depressed mothers compared to the control mothers at any timing of investigation. Even at the fifth postnatal day, 11 of 15 mothers who subsequently became clinical depression had already scored 9 or more, which is indicative of postnatal depression, this means postnatal depression could be detected from the very early postpartum period. As for the validity test of the EPDS, having set a cut-off point being 9 or more, the sensitivity was 82% and the specificity were 95% respectively. This score is the same as Okano reported in Japan and lower than many studies in Western countries. Study II Multi-centre prospective study of early postpartum mood states. SAMPLING AND METHODS: Fourteen obstetric wards in teaching hospitals participated in the study, and there, recruitment in each ward continued until 20 post-natal women had agreed to participate. Two hundred twenty six patients (89.7%) completed the study. During the first 5 days Maternity blues scale, and the EPDS on the 5th postnatal day, and one month postnatally the EPDS again were given to the mothers. The EPDS score of 9 or more was regarded as a probable case of postnatal depression. RESULTS AND DISCUSSION: Seventy-nine out of the 226 patients (35%) had maternity blues. Forty six out of the 226 patients (20%) had postnatal depression (EPDS being 9 or more) at one month postnatally. There was a significant correlation between the EPDS scores on the 5th postnatal day and those at one month. Having maternity blues and higher than 9 or more of the EPDS score were significantly related to the EPDS scores of 9 or more at one month postnatally. (odds's ratio = 4.4 and 13 respectively). Dysphoria on 5 day was significantly related to history of pregnancy loss, Caesarean section, Maternal and neonatal complications and Maternity blues. Dysphoria on one month was only related to Maternal complication. CONCLUSIONS: The onset of postnatal depression can be within the first week after delivery. The use of the EPDS during the first week is a simple and useful screening for early onset case. Maternal complications and related medical factors might be the risk factors of mood disturbance during early postnatal period.     

Prevalence of postnatal depression in Western Nigerian women: a controlled study

Objective The objective of this study is to compare the prevalence of depression in postpartum women and that of non-postpartum women. Method A total of 876 women recruited at 6 weeks postpartum and 900 matched non-postpartum women were administered the Beck's Depressive Inventory (BDI) and translated local version of the EPDS. Psychiatric diagnosis was made using the using the modified non-patient version of Structured Clinical Interview for DSM-III-R (SCID-NP). Results Depressive disorder was diagnosed in 128 (14.6%) of the postpartum women and in 55 (6.3%) of the non-postpartum women, and the difference was found to be significant (t=8.919, df=875, P<0.001). The postpartum women had higher EPDS and BDI scores than the non-postpartum women. The EPDS correlated well with the SCID-NP diagnosis with a Spearman's correlation of 0.600 (P<0.001) and with the BDI score with a Spearman's correlation of 0.461 (P<0.001). The sensitivity of the EPDS at cut-off score of 8/9 was 94% and specificity was 97%. Conclusion The prevalence of postnatal depression in Nigeria is comparable to that of the western world and the Yoruba version of EPDS is a valid instrument for screening postnatal women for depressive disorders in a Nigerian community.     

孕期家庭亲密度适应性对产妇产后抑郁的影响

目的分析孕期家庭亲密度适应性对产妇产后抑郁的影响。方法选取2013-03-2014-03我院收治的晚期妊娠孕妇160例为研究对象,分别于产前和产后6周采用爱丁堡产后抑郁量表和家庭亲密度适应性量表对其进行调查。结果观察组和对照组实际适应性和适应性不满意程度评分相比,差异具有统计学意义(t=-3.509,2.657;P均0.05)。观察组和对照组实际亲密度和亲密度不满意程度评分相比,差异具有统计学意义(t=-2.472,3.005;均P0.05)。实际适应性、适应性不满意程度、实际亲密度和亲密度不满意程度是产后抑郁的影响因素。结果孕期家庭亲密度适应性差会导致产妇产后抑郁,护理人员要重视对家庭亲密度重要性的宣传,降低产妇产后抑郁发生率。     

Risk factors for depression in the first postnatal year

BACKGROUND: The aim of the study was to identify risk factors for depression and to estimate its prevalence in postnatal mothers. METHODS: This cross-sectional and multi-centre study was carried out on 1,350 Turkish women in their first postnatal year. Measures included a structured questionnaire and the Turkish version of the Edinburgh Postnatal Depression Scale (EPDS). RESULTS: Of the women, 31.1% had a score of 13 or higher on the EPDS. The mean score and standard deviation was 9.8+/-5.7. In the multivariate analysis, EPDS scores were significantly associated with economic status, access to support from family members and close friends, emotional distress at the pregnancy, whether the pregnancy was planned, health problems during pregnancy, the perceived standard of baby care after delivery, and mental disorder before and during pregnancy. CONCLUSION: The prevalence of EPDS-based depression among Turkish women in postnatal the period was high, and was associated with several social, economic and demographical factors.