Creating a 21st-Century Intelligent Health System

In most areas of life, Americans enjoy the ease and convenience offered by advances in technology, communications, and transportation. Every day we experience the 21st-century model of America, which is one of effectiveness, accuracy, speed, flexibility, efficiency, lower cost, more choices, and greater achievement. We can shop online, compare prices for goods and services, and when decisions need to be made, we have access to a wide array of information sources to assist in making those decisions. In short, Americans enjoy great latitude in our power to determine what is best for us.This is not, however, the case when it comes to health and healthcare. In our current healthcare system, individuals are dependent on a structure that has resisted the natural progress and modernization achieved by market-oriented, 21st-century industries. The information age has been leaving health behind.Although it is the nature of a science- and technology-based entrepreneurial free market to provide more choices of higher quality at lower cost, in the healthcare sector, prices continue to rise, quality is inconsistent, and individuals lack the information, incentives, and power to make choices.     

水体污染物诱导的叙利亚金黄地鼠胚胎转化细胞中P21蛋白的表达

应用体外叙利亚金黄地鼠胚胎（ＳＨＥ）细胞转化试验和免疫组化的方法，对太湖、巢湖和淀山湖水体有机污染物的致癌活性进行了分析。发现在每瓶（０．０５，０．１，０．２Ｌ）原水浓度范围内，这些有机污染物均可不同程度地诱导ＳＨＥ细胞发生形态学转化，并有一定的剂量反应关系。在典型的Ⅲ型转化细胞中ｒａｓＰ２１蛋白表达明显增高，免疫组化染色阳性，且在过度期Ⅰ、Ⅱ型转化细胞中Ｐ２１已有中等程度的表达。提示太湖、巢湖和淀山湖有机污染物具有一定的致癌活性，ｒａｓ癌基因的激活可能是其诱导ＳＨＥ细胞发生恶性转化的机制之一。