男性勃起功能障碍与心肌梗死的关系分析

目的通过观察男性心肌梗死并发勃起功能障碍患者发生再发性心肌梗死、猝死、心力衰竭的情况,探讨心肌梗死与勃起功能障碍之间的关系。方法随机抽取2006年10月至2007年10月入院的心肌梗死患者53例,并除外有明确病因引起勃起功能障碍者,通过国际勃起功能评分(IIEF-5)评分方法评估男性勃起功能障碍并分为勃起功能正常组与勃起功能障碍组,随访2年,观察两组患者出现再发性心肌梗死、心源性猝死及心力衰竭终点事件的发生率。结果勃起功能障碍组再发性心肌梗死、心源性猝死及心力衰竭的发生率高于勃起功能正常组(P0.05)。结论男性心肌梗死患者并发有勃起功能障碍者预后不良。     

慢性牙周病与勃起功能障碍

勃起功能障碍(erectile dysfunction,ED)和慢性牙周病均是严重影响人类健康的常见病。本文从内皮细胞功能障碍、心血管疾病和糖尿病等三个方面来探讨慢性牙周病导致ED的可能机制。ED是指阴茎持续(至少6个月)不能达到和维持足够的勃起硬度以获得满意的性生活。它作为男性的一种常见病,随年龄的增加而发病率增加[1]。北京1247例已婚男子问卷调查结果表明ED患病率为39.1%,其中40岁以上者为54.5%。60～69岁年龄组重度ED患病率为50～59岁年龄组的近5倍。调查者有心血管疾病史者268例,其中ED患者141例,占52.6%。     

2型糖尿病ED患者维生素A、C、E的变化

勃起功能障碍(ED)不能达到或维持勃起状态以进行满意的性生活,是糖尿病常见的并发症之一。糖尿病患者ED的发生率为35%-70%,是非糖尿病患者发生率的3倍以上[1]。目前认为糖尿病合并ED的发生机制与血管、神经病变,内分泌因素有关。国内外研究表明,糖尿病慢性并发症与维生素(Vit)A     

糖尿病与ED

糖尿病是一种以高血糖为特征的代谢性疾病 ,因其易引起血管和神经病变 ,因此性功能障碍的发生率在此类患者较正常人高 2～ 5倍。男性糖尿病患者常常并发勃起功能障碍 (ＥＤ)、逆向射精、早泄、不射精等性功能异常 ,其中ＥＤ发生率高居首位。糖尿病性ＥＤ可以发生在任何年龄 ,并随年龄增长而上升 ,如 3 0～ 4 0岁的糖尿病患者ＥＤ的发生率约为 1 5% ,至 60岁时可增加到 55%。上述发生率的差异可能与老年患者伴有慢性血管病变有关。另外 ,糖尿病病史越长发生ＥＤ的可能性越大。据国外学者的一项调查报告 ,糖尿病病史在 1 0年以上者发生ＥＤ的…     

中医药治疗糖尿病性勃起功能障碍研究进展

糖尿病性勃起功能障碍(diabetic erectile dysfunc-tion,DED)是糖尿病常见并发症,流行病调查研究显示男性糖尿病患者中ED的发生率为35%~70%,是非糖尿病ED患者的3倍,并随年龄和病程的增长而明显增     

糖尿病性功能障碍患者的心理分析及心理护理

目的 分析糖尿病性勃起功能障碍患的心理状态及总结心理护理要点。方法 分析216例糖尿病性勃起功能障碍患的各种心理状态，针对不同的心理状态，实施个体化心理护理。结果 216例患经过心理护理，均能及时诊治，性生活满意度明显改善。结论 患的心理状态与治疗效果有密切联系，心理护理对治疗糖尿病性勃起功能障碍十分重要。     

茂名市男性2 329例勃起功能调查

目的调查茂名市男性勃起功能障碍患者的发生情况,分析影响男性勃起障碍的相关因素.方法采用中国勃起功能指数(CIEF)健康调查问卷,调查2 329例男性,分析患勃起障碍的478例患者的影响因素.结果2 329例男性中有478例患勃起功能障碍(ED),占20.5%.结论ED的发生不但与年龄有关,还与性交次数,心理因素,心脑血管疾病,糖尿病,高血脂等全身性疾病和家居环境夫妻关系及不良的生活习惯有关.     

溴隐亭治疗男性高泌乳素血症临床研究

目的探讨高泌乳素血症致男性性功能障碍的病因和治疗方法。方法用溴隐亭治疗高泌乳素血症男性患者12例,其临床表现为性欲低下12例,勃起功能障碍10例,生精障碍2例。结果经溴隐亭治疗1～12个月,12例患者的性欲得到提高,勃起功能改善10例,生精障碍2例得到缓解。结论男性高泌乳素血症所致性功能障碍较为少见,溴隐亭治疗效果良好。     

糖尿病性勃起功能障碍相关因素的研究进展

流行病学调查表明,1/3～1/2的男性糖尿病患者会发生勃起功能障碍(erectile dysfunction,ED);而在发生了ED的患者中,40%患有糖尿病[1-2]。男性糖尿病患者与未患有糖尿病的男性人群相比,前者ED的发生率为后者的3～6倍[3-5]。同时,糖尿     

夜间阴茎胀大试验的临床应用及护理

目的 通过夜间阴茎胀大试验找出勃起功能障碍的病因.对象前来泌尿男科检查室行夜间阴茎勃起胀大试验的患者.方法 通过回顾性总结813例主诉勃起功能障碍患者,行夜间阴茎勃起胀大试验.重点系统讨论导致勃起功能障碍的常见因素,介绍检查的意义、优点、方法及护理.结果 813例患者找出勃起功能障碍的病因.结论 夜间阴茎勃起测定系统是针对阴茎勃起障碍的一项特殊检查,可帮助区分心理性勃起功能障碍,确定血管性病因造成的勃起功能障碍,使患者得到合适有效的治疗.     

Prevalence and risk factors for erectile dysfunction in Austria — Analysis of a health screening project

PURPOSE: The aim of this study was to determine prevalence and risk factors for erectile dysfunction (ED) in men undergoing a health investigation. METHODS: Men aged 30-69 yrs participating in a health screening project in the area of Vienna completed a 11-item questionnaire on ED which was extracted from the international index of erectile function (IIEF). In parallel, all men underwent a detailed health examination including physical assessment, evaluation of various life-style factors and a blood analysis with 14 parameters. RESULTS: Within the total study population (n = 832; 45.3 +/- 9.8 yrs), 8.2% reported no sexual intercourse during the previous four weeks, 5.1% reported moderate/severe ED, 13.1% mild and 73.6% no ED. ED, defined as any problem in maintaining erection until the end of sexual intercourse, increased from 12.5% in those aged 30-39 yrs to 15.3% at 40-49 yrs, 27.4% at 50-59 yrs and 45.2% in men 60-69 yrs. In parallel, the percentage of men without sexual intercourse during the previous four weeks increased from 7.4% at 30-39 yrs to 8.8% at 50-59 yrs and 17.0% at 60-69 yrs. By far the strongest correlate for ED was age; other factors were cardiovascular diseases, physical activity and diabetes mellitus. CONCLUSIONS: This study provides the first estimate of the prevalence of ED in different life decades of men in Vienna, and identifies a number of risk factors for this highly prevalent disorder in ageing men.     

Results of micro(vascular) surgical interventions in vascular-induced disorders of erection

In 71 patients aged 20 to 65 years who suffered from erectile dysfunction of vascular (mainly arterial and venous) origin, we performed 66 microsurgical vascular reconstructions (12 according to Michal II, 42 using Virag I, 5 using the Hauri modification and 7 according to the author's own method) and 5 operations to reduce venous outflow from the corpora cavernosa. In addition, 6 Virag I redo reconstructions and other secondary interventions in 18 cases were performed as well as (semi-)conservative therapeutic measures were undertaken. Over a mean follow-up period of 35.1 months 46 out of 56 men were again able to have adequate to normal sexual intercourse. The other patients showed only minimal improvement or their condition remained unchanged. No patient's condition was seen to worsen. The main complications were occlusions of the reconstruction and the hypervascularization syndrome of the penis, affecting 13.3% of the arterio-venous anastomoses. This complication, which often occurred many months postoperatively, was always overcome with banding and in some cases by additional venous ligatures so that a functional reconstruction remained in all but one case. In cases of erectile dysfunction of vascular origin, vascular surgery presents the most natural form of therapy and therefore deserves consideration before life-long auto-injection therapy is prescribed for the corpora cavernosa or the implantation of a penis prosthesis is considered. Specific angiological investigation is advisable in all cases in which a four- to six-month course of (semi-)conservative treatment does not bring long-term success.     

异常勃起的局部注射治疗及其治愈后勃起功能的探讨(附31例报道)

目的:探讨去甲肾上腺素阴茎海绵体注射治疗异常勃起的效果及长时间异常勃起经治疗后对其勃起功能的影响。对象与方法:应用去甲肾上腺素0.5mg 海绵体注射治疗31例36次异常勃起。异常勃起发生时间为 7～120小时,平均 23.7小时,并对 27例作了随访。结果:全部治愈,近期内无明显不良后果。除 4例失访外,其余 27例作了 8个月～11年(平均 5.4年)的随访。患者短期内勃起功能与发病前无显著差别。但在6个月后,异常勃起超过36小时的11例中有9例发生勃起功能障碍(82％)和4例发生海绵体纤维化(36％)。而在36小时以内的16例中只有5例有勃起功能障碍(36.25％,x~2=4.78,P<0.05)。结论:海绵体内注射去甲肾上腺素是治疗异常勃起有效而安全的方法。超过36小时的异常勃起可能导致勃起功能障碍。其原因与海绵体的纤维化可能有一定的关系。     

Injections of papaverine and regitine into the corpora cavernosa for erectile dysfunction: clinical results in 60 patients

After evaluating approximately 500 patients to identify the cause of erectile dysfunction, I selected 60 patients to receive a therapeutic injection of the vasoactive drugs papaverine and phentolamine mesylate (Regitine) into the corpora cavernosa. Fifty-two patients (87%) obtained erections that were adequate for sexual intercourse; these patients continued a self-injection program. Older patients with vasculogenic erectile dysfunction responded poorly. Ten patients, seven of whom had responded adequately, subsequently had implantation of a penile prosthesis. Although the self-injection group had few complications, 16 of 30 patients (53%) who had long-term follow-up subsequently discontinued the injections.     

Sildenafil citrate (viagra) treatment in patients with diabetes mellitus

AIM: To evaluate different dosages of vasoactive drug viagra in patients with erectile dysfunction suffering from diabetes mellitus (DM) type I and II. MATERIALS AND METHODS: Viagra in doses 25, 50 and 100 mg was given to 30 DM patients with different forms of erectile dysfunction. RESULTS: The response was obtained in 70.3% of cases. The highest effect was achieved with the dose 100 mg (the response rate 68.5% of patients). The dose 50 mg was effective in 31.5%, 25 mg in 0% of patients. Most nonresponders had low testosterone levels in the blood.     

Erectile dysfunction and coronary atherothrombosis in diabetic patients: pathophysiology, clinical features and treatment

The current review reports recent data available in the literature on the prevalence of erectile dysfunction and the association of erectile dysfunction with overt and silent coronary artery disease in patients with diabetes mellitus. The mechanisms by which erectile dysfunction is associated with coronary artery disease and potential clinical implications of this association have been extensively analysed. In particular, the role of endothelial dysfunction in the pathophysiology of erectile dysfunction and the potential clinical usefulness of erectile dysfunction to identify diabetic patients with silent coronary artery disease have been outlined. Finally, recent guidelines on the treatment of erectile dysfunction with phosphodiesterase-5 inhibitors in diabetic patients with and without coronary artery disease have been reported and discussed.     

芎蒌通脉方联合西地那非治疗痰瘀型2型糖尿病性勃起功能障碍临床研究

目的:探讨芎蒌通脉方联合西地那非治疗痰瘀型2型糖尿病性勃起功能障碍的临床效果。方法:选取2017年1月～2018年3月我院门诊收治的60例痰瘀型2型糖尿病性勃起功能障碍患者,随机分为西药组和联合组,每组30例。西药组给予西地那非治疗,联合组给予芎蒌通脉方联合西地那非治疗。观察两组治疗前后的IIEF-5、中医主症积分、性交满意度和临床疗效。结果:治疗8周后,联合组的IIEF-5评分明显高于西药组,差异有统计学意义,P0.05;联合组的中医主症积分明显低于西药组,差异有统计学意义,P0.05;联合组的性交满意度为83.3%,明显优于西药组的66.7%,差异有统计学意义,P0.05;联合组的临床总有效率为90.0%,明显高于西药组的73.3%,差异有统计学意义,P0.05;两组均未出现明显不良反应。结论:芎蒌通脉方联合西地那非可以进一步提高治疗痰瘀型2型糖尿病性勃起功能障碍临床疗效,增强患者阴茎勃起功能和勃起质量,改善患者的性交满意度。     

Sexual function in ICU survivors more than 3 years after major trauma

Objective To study sexual function in trauma patients 3–8 years after discharge from an ICU and to assess determinants of poor sex life. Design and setting A postal questionnaire survey was conducted in 2006 on a cohort of 325 consecutive adult ICU trauma patients admitted to a university hospital during 1998–2003. Patients Of 210 eligible patients 156 (74%) answered the questionnaires. Mean age was 46 years, and 124 were males. Measurements and results Sexual function was assessed by a self-report measure, and patients were asked to describe sexual life both currently and prior to trauma. The International Index of Erectile Function evaluated erectile function in males. At follow-up 50% reported sexual function to be unchanged, 41% impaired, and 9% to be better than preinjury status; 34% reported that the trauma impaired current sex life. Erectile dysfunction was found in 27% of men younger than 40 years and 51% of men 40 years or older. Age, being single, Injury Severity Score, and depression were associated with poor sexual function. Of 17 patients experiencing breakdown of a regular relationship 71% reported the trauma to be a significant contributor. Conclusions At follow-up more than 3 years after injury one-third of our ICU trauma patients reported that the trauma impaired sexual function. Erectile dysfunction was significantly more frequent among men younger than 40 years than found in studies of the normal population. Evaluation of sexual function should be part of long-term outcome assessment after major trauma. Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users.     

Pudendal nerve conduction to evaluate organic erectile dysfunction

OBJECTIVE: This study aimed to evaluate the value of testing pudendal nerve conduction in men with erectile dysfunction. DESIGN: This open prospective study was conducted on 150 men with documented erectile dysfunction of at least 6 mo of duration, all of whom underwent pudendal nerve conduction by the same investigator. RESULTS: Only patients with erectile dysfunction and low back pain (n = 9) showed statistically significant prolonged pathologic pudendal nerve conduction latency of 43.1 msec/div (SD +/- 11.3 msec/div, P < 0.05). There were no correlations between the pudendal nerve conduction latency in patients suffering from erectile dysfunction associated with diabetes mellitus, local trauma, pelvic surgery, or antihypertensive drugs. CONCLUSIONS: Pudendal nerve conduction may contribute valuable information to the evaluation of patients with erectile dysfunction caused by neurologic deficits as manifested by low back pain.     

Population-based burden of bloodstream infections in Finland

Bloodstream infections (BSI) are a major cause of mortality, morbidity and medical cost, but few population-based studies have concomitantly evaluated BSI incidence and mortality. Data on BSI episodes reported to national, population-based surveillance by all clinical microbiology laboratories in Finland during 2004-07 were linked to vital statistics. Age-, sex and microbe-specific incidence and mortality rates were calculated. During 2004-07, 33 473 BSI episodes were identified; BSI incidence increased from 147 to 168 per 100 000 population (average annual increase, 4.4%; p <0.001). Rates were highest among persons ≥65 years and <1 year, and higher among male patients than female patients (166 versus 152 per 100 000). The most common aetiologies were Escherichia coli (27%) and Staphylococcus aureus (13%). Among male patients, 52% of BSI were caused by gram-positive bacteria compared with 42% among female patients (p <0.001). The overall 30-day case-fatality was 13%. Of the deaths, 32% occurred within 2 days, 70% were among people aged 65 years or more and 33% were caused by E. coli or S. aureus infections. The BSI mortality rate increased from 19 to 22 per 100 000 (average annual increase: 4.0%, p 0.01). Among people aged 25 years or more, the mortality rate was 1.4-fold higher in men than women (34 versus 25 per 100 000 population). Overall excess annual mortality from BSI in the population was 18 per 100 000. The substantial BSI burden among the elderly and among adult men highlights the need for developing and implementing effective interventions, particularly for BSI caused by E. coli and S. aureus. One-third of BSI deaths occurred early, emphasizing the importance of early identification and treatment.