注射用冻干丹参治疗糖尿病周围神经病变62例

目的观察注射冻干丹参对糖尿病周围神经病变的疗效。方法治疗组62例采用注射用冻干丹参配合西药治疗，并与单用西药50例对照治疗进行疗效对比观察。结果治疗组总效率为90.3％，对照组为58．0％，p〈0．01（x^2=24．397）在神经传导速度变化方面，两组治疗前后自身及两组治疗后比均较有显著提高（p〈0．05和p〈0．01）；在改善血液流变学方面，治疗组治疗后较治疗前改善有显著性p〈0．01，治疗后两组比较亦有显著性差异（p〈0．05和p〈0．01），但对照组自身比较p〉0．05。结论冻干丹参注射液治疗糖尿病周围神经病变疗效确切。     

参麦注射液辅助治疗慢性充血性心力衰竭的疗效观察

目的探讨参麦注射液对充血性心力衰竭（CHF）患者的心功能影响及疗效。方法120例CHF患者随机分为对照组和治疗组各60例，对照组采用西药常规治疗，治疗组在对照组治疗的基础上加40ml参麦注射液辅助治疗，Qd，疗程为2wk。于治疗前后测定两组左心室收缩末期容积（LVESV）和左心室舒张末期容积（LVEDV），并进行临床疗效评价。结果两组治疗后LVESV较治疗前均明显改善，均p〈0．01（t=48．810，3．846）；治疗后治疗组LVESV改善明显优于对照组p〈0．01（t=2．833）。治疗组临床总有效率为83．4％，明显高于对照组的63．3％，p〈0．05（x^2=6．148）。结论参麦注射液能明显改善CHF患者的临床症状和心功能，可作为治疗CHF安全有效的辅助药物。     

泮托拉唑治疗胃溃疡的疗效观察

目的观察泮托拉唑治疗胃溃疡的临床疗效。方法采用随机抽样，配对分组法将128例胃溃疡患者分为泮托拉唑组和雷尼替丁对照组。结果泮托拉唑对胃溃疡的8wk治愈率为92．19％，明显高于雷尼替丁组的68．75％，p〈0．01；（x^2=11．184）；且副作用少，总有效率分别为96．9%（62/64）和87．5（56／64），p〈0．05（x^2=3．905）。结论泮托拉唑治疗胃溃疡疗效显著。     

双氯芬酸钠栓用于尿路结石镇痛疗效观察

目的探讨双氯芬酸钠栓用于尿路结石镇痛的临床疗效。方法选择2008年6月～2010年6月我院收治的尿路结石绞痛患者80例,随机分为观察组和对照组各40例。观察组双氯芬酸钠栓直肠给药lOOmg,对照组肌肉注射杜冷丁50rag,阿托品0．5mg。结果观察组用药后总有效率为92．5％（37／40）,30min内总有效率达70．0％（28／40）,均明显高于对照组的72．5％（29／40）和37．5％（15／40）,差异有显著性意义（x^2=7．81,P〈0．05;x^2=8．50,P〈0．01）;观察组不良反应发生率7．5％（3／40）,明显低于对照组的30．0％（12／40）,差异有显著性意义（x^2=6．65,P〈0．01）。结论双氯芬酸钠栓用于尿路结石镇痛疗效确切、给药方便、起效快、不良反应少,值得临床推广应用。     

祛栓合剂颈动脉灌注治疗前循环脑梗死的疗效观察

目的观察祛栓合剂颈动脉灌注治疗前循环脑梗死（ACI）的临床疗效及安全性。方法选择起病96h以内的ACI患者共125例,随机分成研究组63例、对照组62例,在常规脑梗死治疗基础上,研究组给予祛栓合剂病灶侧颈动脉灌注治疗,每天一次;对照组给予血塞通750mg静脉点滴,每天一次,15d为一疗程。分别于治疗前、治疗结束和治疗结束后2周进行CSS评分。结果对神经功能缺损的恢复,研究组明显优于对照组（P〈0．01）。结论祛栓合剂颈动脉灌注是治疗ACI有效、安全、易行的方法。     

依拉普利治疗中青年高血压的疗效观察

目的观察依拉普利治疗中青年原发性高血压（尤以舒张压增高为主）的临床疗效及安全性。方法将43例中青年高血压患者分为依拉普利治疗组和尼群地平对照组，进行疗效观察对比。结果总有效率治疗组95．7％，对照组55％，两组有显著差异p〈0．01（x^2=9．906）。结论依拉普利治疗中青年人原发性高血压，疗效好，安全性高，预后好。     

东莨菪碱在婴幼儿毛细支气管炎治疗中的作用

目的 探讨有效治疗方法，观察东莨菪碱对毛细支气管炎的疗效。方法 将90例毛细支气管炎的患者分成治疗组和对照组各45例，对照组给予抗病毒、抗生素预防和治疗混合感染、雾化吸入等治疗；治疗组在对照组基础上加用东莨菪碱每次0．03-0．05mg·kg^-1，间隔6．8h，连用3．5d，对两组疗效进行比较分析。结果 治疗组病程（6．8±1．1）d，对照组（9．7±2．5）d，治疗组病程明显短于对照组p〈0．01（x^2=7．122）。治疗组治愈率80．0％，有效率97．8％；对照组治愈率48．9％，有效率88．9％。两组治愈率比较治疗组显著高于对照组p〈0．01（u=3．187）：治疗组症状及肺部体征消失时间均短于对照组p〈0．01。结论 东莨菪碱治疗毛细支气管炎改善症状明显、缩短病程、无严重不良反应。     

针灸与正清风痛宁注射液治疗痛风35例临床观察

目的 观察针灸与正清风痛宁注射液治疗痛风的临床疗效。方法 治疗组采用针灸与正清风痛宁注射液直流电导入治疗痛风35例并与单纯采用针灸治疗的对照组32例疗效对此观察。结果 治疗组和对照组的总有效率分别为97．1％、71．9％，p〈0．05（x^2=9．271）。两组治疗后血尿酸较治疗前显著降低，治疗组更低于对照组p〈0．01。结论 针灸配合正清风痛宁注射治疗痛风疗效满意。     

鼻咽癌病人的心理护理

目的：针对鼻咽癌病人的心理问题进行心理护理以减少其焦虑心理，提高治疗效果。方法：将118例鼻咽癌病人随机分成两组，对照组作一般常规护理，观察组在常规护理的基础上加作系统的心理护理，比较两组住院1mo后心理状态。结果：两组治疗前后各自比较，均有显著性差异p〈0．05（x^2=7．869）和p〈0．01（x^2=40．109）：治疗后观察组更优于对照组p〈0．01（x^2=12．206）。结论：通过心理护理，减少病人的心理问题，提高了生存质量。     

尿道灌注治疗男性非淋菌性尿道炎101例

将186例非淋菌性尿道炎患者随机分为治疗组101例，从尿道内灌注左氧氟沙星＋口服阿奇霉素；对照组85例，口服左氧氟沙星及阿奇霉素。结果表明，治疗组和对照组总有效率分别为93．1％、84．7％，两组比较差异无统计学意义（x^2=3．36，P〉0．05），痊愈率分别为82．2％、55．3％，两组比较差异有统计学意义（x^2=12．72，P〈0．01）。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.