建平烧锅营子金矿D级储量误差评述

烧锅营子金矿探采对比结果：206脉地质储量全部落空；207脉C＋D级地质储量变级生产储量矿石量减少71．00％，金属量减少54．33／，其中D级储量减少幅度更大，矿石量81．13％，金属量67．38％．虽然表外D级地质储量变表内生产储量矿石量8069t，金属量165．86kg．新增生产储量矿石量9893t，金属量203．69kg．但变级生产储量与地质储量相比较，仍向负值变化．究其原因系矿作勘探类型和矿块落空，矿体厚度变薄，形态复杂多变及金组份分布极不均匀等各种地质因素变化所致．     

河北窄岭金矿大营子矿区保有地质储量分析

在详细研究矿山地质资料及实地调查的基础上,按地质块段法对窄岭金矿大营子矿区保有地质储量进行了计算,结果表明矿区原定保有地质储量矿石县为407499t,金属量为2429kg;实际保有地质储量矿石量为201598t,金属量为1244kg．大营子金矿储量负变的主要原因是勘探过程中深部矿体的连接问题．     

河北窄岭金矿大营子矿区保有地质储量分析

在详细研究矿山地质资料及实地调查的基础上,按地质块段法对窄岭金矿大营子矿区保有地质储量进行了计算,结果表明矿区原定保有地质储量矿石量为407499t,金属量为2429kg;实际保有地质储量矿石量为201598t,金属量为1244kg。大营子金矿储量负变的主要原因是勘探过程中深部矿体的连接问题。     

世界铅锌资源开发现状及其利用

资源储量概况 世界已查明的铅资源量15亿多吨,铅储量7900万吨,储量基础17000万吨。世界铅资源主要分布在澳大利亚、中国、美国和哈萨克斯坦四国,占世界储量的60．3％,占世界储量基础71．2％。世界已查明的锌资源量19亿多吨,锌储量18000万吨,储量基础48000万吨。世界锌资源主要分布在澳大利亚、中国、秘鲁、美国和哈萨克斯坦五国,占世界储量的67．2％,占世界储量基础70．9％。     

冶金动态

一、综合 ●攀钢西昌项目紧邻攀西矿区．已探明钒钛磁铁矿的储量达到96．6亿t,其中原生钛铁矿二氧化钛资源储量为6．18亿t,占全国储量的95％;五氧化二钒储量为1580万t,占全国储量的62．2％,铁资源储量为25亿t以上,是居于鞍本矿区之后的中国第二大矿区。     

我国有色金属探明资源储量持续上升

我国有色金属探明储量持续上升。中国有色金属工业协会的数据表明,到目前为止,全国查明资源储量：铜8026．3万吨,其中基础储量2951万吨;铅4851．1万吨,其中基础储量1340．1万吨;锌10695．3万吨,其中基础储量3838．5万吨;铝土32．0亿吨,其中基础储量8．39亿吨（矿石量）。     

山东夏甸金矿区北耩金矿床深部成矿预测标志

山东夏甸金矿区北耩金矿床正处于资源危机状态,在深部或外围寻找隐伏矿体则显得尤为重要。通过综合地质找矿标志的建立,认为北耩金矿体极可能延伸到矿区外围,地表西侧有多处金矿化,同时预测深部储量约624．328kg。     

中国铜资源的现今与未来

资源和储量 1．累计查明资源储量 据国土资源部全国矿产储量数据库2009年的统计数据,建国以来至2008年底,全国累计查明铜资源储量9949．74万吨。1985年至2000年查明资源储量增长缓慢,15年间增加了约1000万吨。2000年后恢复快速增长。     

一、储量与储量基础

一、储量与储量基础１．矿山产量、矿产储量及其可采年数注：＊其定义见第１３页说明；１、矿山产量及储量数据取自美国矿务局１９９５年发表的《矿产品概览》；２．可采年数是根据上述储量和１９９４年矿产量计算的，也称＂储量静态寿命＂；；３．锂储量未包括中国的，故...     

菲律宾镍资源概况

1、储量及分布 截止至1996年，菲律宾镍矿总储量达到11亿公吨。其中，已探明储量10亿吨，占总储量的93．72％。平均品质范围在0．23％-2．47％。可期储量5630万吨，占5．17％，品质范围在0．36％～1．24％。还有1210万吨为可能储量，品质范围在0．23％～2．27％（注：总储量为探明的储量、可期储量和可能储量之和）。按地质分类，菲镍矿多为红土带（占99％）。由于大部分镍矿处在浅土层，易于开采且成本低。     

Electrophysiological evidence for a large receptor reserve for inhibition of dorsal raphe neuronal firing by 5-HT1A agonists

Previous studies [Meller et al. (1990) Mol. Pharmacol., 37:231-237] have shown that a large receptor reserve exists for the inhibition of serotonin synthesis in rat cortex and hippocampus by the 5-HT1A agonist 8-hydroxy-2(di-n-propylamino)tetralin (8-OH-DPAT), whereas little or no reserve exists for the lower efficacy agonists ipsapirone and BMY 7378. The current studies were undertaken to determine if the above drugs exhibit similar relative efficacies and receptor reserves in an electrophysiological model of 5-HT1A receptor activation, i.e., the inhibition of dorsal raphe cell firing. Intravenous dose-response curves were constructed in untreated control rats, or in rats which received an injection of the irreversible receptor inactivator N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ, 6 mg/kg, s.c.) 24 hours before recording. All three drugs fully inhibited dorsal raphe cell firing in control rats (ED50's: 1.5 micrograms/kg, 8-OH-DPAT; 30.0 micrograms/kg, ipsapirone; 17.5 micrograms/kg, BMY 7378). However, unlike effects on serotonin synthesis, EEDQ treatments caused no depression of the maximal inhibitory response for any of the agonists, although all dose-response curves were shifted to the right (ED50's: 10.1 micrograms/kg, 6.7-fold shift, 8-OH-DPAT; 139.9 micrograms/kg, 4.7-fold shift, ipsapirone; 53.8 micrograms/kg, 3.1-fold shift, BMY 7378). Although the order of agonist efficacies was similar for both inhibition of serotonin synthesis and dorsal raphe cell firing (8-OH-DPAT > ipsapirone > BMY 7378), a large (> 50%) receptor reserve was estimated for all three drugs in this electrophysiological system.(ABSTRACT TRUNCATED AT 250 WORDS)     

Changes in cardiac autonomic activities in patients with syndrome X. A study of spectral analysis of heart rate variability

The present study was designed to assess cardiac autonomic activities, coronary microvascular function, and their relationship in patients with syndrome X. Control of coronary blood flow is complex, and impaired coronary flow reserve has been attributed as the cause of myocardial ischemia in patients with syndrome X. It is unknown whether cardiac autonomic activities are altered in the presence of coronary microvascular dysfunction in patients with syndrome X. Eighteen patients with syndrome X were studied. Great cardiac vein flow was measured by the thermodilution method and the coronary flow reserve was determined by intravenous dipyridamole (0.56 mg/kg) infusion. Twenty-four-hour ambulatory electrocardiograms were obtained in a drug-free state. Another 14 age- and sex-matched normal subjects served as a control group. The amplitude (in ms) of ultralow (ULF), very-low (VLF), low (LF), and high (HF) frequency bands and total spectra of heart rate variability were measured for twenty-four-hour and every four-hour interval of the day.     

小块焦对高炉焦比的影响

在高炉冶炼过程中小块焦一直被认为只是作为资源再利用,使用时常常不被看好。通过实验室的探索性研究,了解到小块焦的粒度效应对其失重率作用很大,小块焦的反应性相对于冶金焦有很大的提高。可以认为小块焦在炉内改善了还原性,有促进矿石还原作用。小块焦的大量气化吸热有降低热储备区温度的倾向,对高炉的燃料消耗进一步降低起了一定作用。750 m3高炉的生产性试验结果表明,提高小块焦的用量有利于燃料消耗的降低,其他工艺参数不变,增加1 kg/t的小块焦相当于置换焦比1.19 kg/t。     

大桥金矿Ⅰ-1矿体地质储量估算

地质找矿、评价、勘探到矿山开采的各个阶段,都要进行储量估算。大桥金矿Ⅰ-1矿体具有层状、倾角缓、厚度大等特征。结合多年地质找矿成果,采用水平平行断面法,对大桥金矿Ⅰ-1矿体划分了98个小块段矿体,并对其地质储量进行了估算,获得大桥金矿Ⅰ-1矿体工业矿体与低品位矿体总矿石量202.69万t,Au总金属量4 013 kg,Au平均品位1.98×10~(-6)。查明了大桥金矿Ⅰ-1矿体部分资源/储量,为下一步大桥金矿Ⅰ-1矿体开发利用提供了资源保障。     

Relation among stenosis severity, myocardial blood flow, and flow reserve in patients with coronary artery disease

BACKGROUND: Coronary arteriography is considered the "gold standard" for evaluating the severity of a coronary stenosis. Because the resistance to blood flow through a stenotic lesion depends on a number of lesion characteristics, the physiological significance of coronary lesions of intermediate severity is often difficult to determine from angiography alone. This study of patients with coronary artery disease seeks to determine the relation between myocardial blood flow and flow reserve measured by positron emission tomography (PET) and the percent area stenosis on quantitative coronary arteriography. METHODS AND RESULTS: We studied 28 subjects: 18 patients with coronary artery disease (66 +/- 8 years) and 10 age-matched healthy volunteers (64 +/- 13 years) with dynamic N-13 ammonia PET imaging at rest and after dipyridamole (0.56 mg/kg). The percent cross-sectional area stenosis was quantified on the coronary arteriograms as described by Brown et al. In the 18 patients, a total of 41 non-infarct-related coronary vessels were analyzed. Myocardial blood flows in normal regions of patients with coronary artery disease were not different than those in healthy volunteers, both at rest and after dipyridamole. As a result, the myocardial flow reserve was also similar in both groups (2.4 +/- 0.4 versus 2.6 +/- 0.7, respectively; P = NS). Quantitative PET estimates of hyperemic blood flow (r = .81, P < .00001), flow reserve (r = .78, P < .00001), and an index of the "minimal coronary resistance" (r = .78, P < .00001) were inversely and nonlinearly correlated with the percent area stenosis on angiography. Of note, PET estimates of myocardial flow reserve successfully differentiated coronary lesions of intermediate severity (50% to 70% and 70% to 90%; 2.4 +/- 0.4 versus 1.8 +/- 0.5, respectively; P = .04). CONCLUSIONS: In patients with coronary artery disease, non-invasive measurements of myocardial blood flow and flow reserve by PET are inversely and nonlinearly related to stenosis severity as defined by quantitative angiography. Importantly, coronary lesions of intermediate severity have a differential flow reserve that decreases as stenosis increases that can be detected noninvasively by PET, thus allowing better definition of the functional importance of known coronary stenosis.     

Myocardial perfusion reserve studied by single-photon emission-computed tomography with thallium-201 and a drug stress test with adenosine triphosphate in patients with cardiovascular risk factors

INTRODUCTION AND OBJECTIVE: Recent studies have suggested that the evaluation of coronary reserve is a sensitive method in the early detection of vascular alterations before plaques exist, and certainly before clinical detection of atherosclerotic lesions. Single-photon emission-computed tomography (SPECT) with thallium-201 (201Tl) provides a noninvasive tool for evaluating myocardial perfusion reserve. The objective of this study was to measure the myocardial perfusion reserve in two groups of subjects, some with and some without cardiovascular risk factors and in a group of patients with coronary artery disease. METHODS: Seventy-four subjects, divided into three groups, were recruited to assess regional and global myocardial perfusion reserve. The control group consisted of 11 asymptomatic individuals without cardiovascular risk factors. The second group was composed of 49 patients with one or more risk factors. Finally, the third group included 14 patients with coronary artery disease. 201Tl-SPECT at rest and after pharmacological stress with a 7 minute adenosine triphosphate (ATP) infusion (140 micrograms/kg/min) was performed in all patients. ATP minus rest value subtraction was applied in order to obtain the stress data. Relative myocardial perfusion reserve indices were calculated as the ratio between stress and rest values. RESULTS: Global and regional myocardial perfusion reserves of the vascular territories were significantly lower in patients with cardiovascular risk factors than in control subjects (Global: 1.48 +/- 0.19 vs 1.81 +/- 0.08, LAD: 1.52 +/- 0.21 vs 1.85 +/- 0.09, CX: 1.45 +/- 0.2 vs 1.79 +/- 0.86, RCA: 1.47 +/- 0.2 vs 1.79 +/- 0.86) and higher than in patients with coronary artery disease (Global: 1.48 +/- 0.19 vs 1.31 +/- 0.14, LAD: 1.52 +/- 0.21 vs 1.35 +/- 0.15, CX: 1.45 +/- 0.2 vs 1.2 +/- 0.24). Univariate linear regression analysis in a group of 40 patients with high risk lipid profiles revealed a significant negative correlation between myocardial perfusion reserve and total cholesterol (r = -0.35; p = 0.01), LDL-cholesterol (r = -0.38; p = 0.036) and LDL/HDL ratio (r = -0.39; p = 0.029). CONCLUSION: Determination of myocardial perfusion reserve with 201Tl-SPECT allows the detection of abnormal vasodilatory response to intravenous ATP in patients with cardiovascular risk factors. These patients have higher reserves than patients with coronary disease, which might suggest an early phase of atherosclerosis.     

Alterations of the architecture of subendocardial arterioles in patients with hypertrophic cardiomyopathy and impaired coronary vasodilator reserve: a possible cause for myocardial ischemia

OBJECTIVES: The study was designed to investigate the architecture of subendocardial arterioles of patients with hypertrophic cardiomyopathy (HCM) and angina pectoris with respect to coronary vasodilator reserve. BACKGROUND: There is growing evidence that the coronary microvasculature is abnormal in HCM. Arterioles, which mainly regulate intramyocardial blood flow, are especially suspect. METHODS: Thirteen patients with HCM (50.1+/-12.6 years old, mean value +/- SD) were studied after exclusion of any relevant coronary stenoses. Subendocardial arterioles (density [n/mm2], wall area [microm2], percent lumen area [%lumen], periarteriolar collagen area [microm2]), myocyte diameter (microm) and interstitial collagen fraction (Vv%) were evaluated by means of stereologic morphometry of transvenous biopsy samples. Coronary blood flow was measured quantitatively with the inert chromatographic argon method at basal conditions and after dipyridamole (0.5 mg/kg body weight over 4 min intravenously), and coronary vasodilator reserve was calculated as the ratio of coronary resistance at basal conditions and after pharmacologic vasodilation. Data from five normotensive subjects (45.4+/-11 years old, p = NS) served as control data. RESULTS: Arteriolar density was diminished by 38% (p = 0.004) and %lumen by 13% (p = 0.009) in patients with HCM compared with control subjects. Coronary reserve was impaired in patients with HCM (2.28+/-0.6 vs. 5.34+/-1.49, p = 0.003) because of higher coronary resistance after vasodilation (0.48+/-0.14 vs. 0.22+/-0.06 mm Hg x min x 100 g/ml, p = 0.004). Coronary vasodilator reserve correlated with arteriolar density (r = +0.47, p = 0.045) and with %lumen (r = 0.65, p = 0.003). CONCLUSIONS: In HCM, the architecture of preterminal subendocardial arterioles is altered by a reduced total cross-sectional lumen area, corresponding to an impaired coronary vasodilator capacity that may predispose to myocardial ischemia.     

Long-term antihypertensive therapy with isradipine. Improvement of coronary flow reserve in patients with arterial hypertension and microvascular angina

Antihypertensive Long-term Therapy with Isradipine/Improvement of coronary flow reserve in patients with arterial and microvascular angina In patients with arterial hypertension coronary flow reserve is often impaired due to left ventricular (LV) hypertrophy and alterations of the coronary microcirculation. Experimental and clinical studies have shown that calcium channel blockers can induce regression of myocardial hypertrophy. Objective of the present study was to see whether chronic antihypertensive treatment with calcium channel blockers can improve the diminished coronary reserve in patients with arterial hypertension and microvascular angina pectoris. Fifteen hypertensive patients with microvascular angina (61 +/- 7 years, normal coronary angiogram, mild LV-hypertrophy) were treated with isradipine (CAS 75695-93-1) (5.3 +/- 0.9 mg/d) for 12 +/- 2 months. Before and after therapy (after a washout period of 1 week) coronary flow was quantitatively measured by the gas chromatographic Argon method. Coronary reserve was calculated as the quotient of coronary resistance under baseline conditions and after dipyridamole (0.5 mg/kg i.v.). Under isradipine therapy systolic blood pressure was lowered from 165 +/- 20 to 140 +/- 13 mmHg (p < 0.01) and diastolic blood pressure from 98 +/- 8 to 88 +/- 6 mmHg (p < 0.01). The LV muscle mass index decreased by 10% from 154 +/- 33 to 139 +/- 28 g/m2 (p < 0.05). Baseline coronary blood flow (81 +/- 13 versus 83 +/- 16 ml/min x 100 g, n.s.) was identical before and after therapy. There were also no differences in coronary perfusion pressure, heart rate, myocardial oxygen consumption and arterio-coronary venous oxygen difference before and after therapy.(ABSTRACT TRUNCATED AT 250 WORDS)     

Inotropic reserve and histological appearance of hibernating myocardium in conscious pigs with ameroid-induced coronary stenosis

Inotropic reserve, demonstrated with administration of sympathomimetic amines, is characteristic of hibernating myocardium. The goal of this study was to determine whether inotropic reserve was present following chronic coronary artery constriction in the pig, which is one potential model of hibernating myocardium. The effects of isoproterenol were examined in five conscious pigs 21 +/- 2.1 days after ameroid implantation on the left circumflex coronary artery on measurements of left ventricular (LV) pressure, LV dP/dt, and regional wall thickening in the ameroid-dependent zone (posterior wall) and contralateral non-ischemic zone (anterior wall). Isoproterenol, 0.1 microgram/kg/min, increased LV dP/dt by 96 +/- 11%, heart rate by 43 +/- 13 beats/min, and normalized systolic wall thickening, slightly, but not significantly more in the ameroid-dependent zone (+1.57 +/- 0.31 mm) than in the contralateral non-ischemic zone (+1.04 +/- 0.31 mm), although the baseline wall thickening was reduced significantly in the ameroid-dependent zone. This occurred at a time when baseline myocardial blood flow was preserved and myocardial perfusion in the ameroid-dependent zone was derived in part from the native coronary circulation and also through collateral channels. Two weeks later histological evidence of lesions characteristic of hibernating myocardium, i.e., myofibrolysis and increased glycogen deposition, were observed. Thus, these histological changes and the confluence of chronically depressed regional function and residual inotropic reserve in the conscious pig with chronic ameroid-induced coronary constriction support this model for further study of hibernating myocardium.