退休接尘矿工肺功能损害的配对研究

目的：研究退休接尘矿工的肺功能损害情况。方法：在某镍矿对退休接尘矿工和对照矿工进行了肺功能的配对研究。结果：不论吸烟与否，退休接尘矿工的ＦＶＣ、ＦＥＶ１Ｖ７５、Ｖ５０等肺功能指标的实测值、实测值占预计值％较对照组明显降低，异常率则显著升高（Ｐ＜０．０５或０．０１）。结论：退休接尘矿工肺功能损害仍然存在，应引起重视。     

海洛因吸入者的肺功能初步观察

目的探讨吸入海洛因对肺功能的影响．方法对７０例海洛因依赖者（包括吸毒组３７例，戒毒组３３例）进行了ＦＶＣ、ＦＥＶ１０、ＰＥＦ、ＦＥＦ２５～７５、Ｖ５０五项指标测定，并与正常对照组（ｎ＝２５）和戒毒组比较．结果吸毒组的肺功能与对照组比较显著下降（Ｐ＜０．０１），而戒毒组与吸毒组比较，肺功能更有一定程度恢复（Ｐ＜０．０１），但仍显著低于对照组（ＦＶＣ，ＦＥＶ１．０，Ｖ５０，Ｐ＜０．０１，余指标Ｐ＜０．０５）．结论吸入海洛因损害了小气道功能及肺通气功能，戒毒后恢复慢．     

棉尘及吸烟对肺功能影响的观察

对８３名接触棉尘的健康者作肺功能测定，并与３９名不接触棉尘的健康者对照。其中男性均为吸烟者；女性均为不吸烟者。结果表明，ＭＭＥＦ、ＰＥＦＲ、Ｖ２５％～７５％均明显低于对照组（分别为Ｐ＜０．０１和Ｐ＜０．０５）．在男性吸烟组，ＶＣ，ＭＢＣ，ＦＥＶ１％也有明显下降（Ｐ＜０．０１），作者认为棉尘对人体的危害主要部位在小气道，吸烟者因损害严重可累及大气道。以往对棉尘反应的肺功能评估仅以ＦＥＶ１％为指标，不能反映早期的变化，有必要进一步完善。     

木尘对接尘工人肺功能急性影响的研究

目的：探讨木尘对接尘工人肺功能的急性影响。方法：运用Ｔ检验方法对某厂木型车间５２名接触木尘工人肺功能进行了分析。结果：接尘组ＦＶＣ、ＦＥＶ１、ＭＭＦ、Ｖ５０与Ｖ２５班中实测值均较班前明显降低，其差值具有非常显著的统计学意义。与对照组相比，接尘组肺功能各项指标的异常急性改变率显著增高（Ｐ均＜０．０１）。接尘组班前肺功能各项指标实测值占预计值百分比均较对照组明显降低，并具有非常显著的统计学意义。结论：木尘对接尘工人的肺功能可能有急性影响作用。     

铸造粉尘对接尘工人肺功能的影响及其因素分析

对１５５０名铸造接尘工人及７３８名对照工人进行了肺功能测定与呼吸系统症状的询问调查。结果表明：接尘组工人的咳嗽、咯痰、胸闷、胸痛、气短等呼吸系统症状阳性率明显高于对照组；肺功能ＦＶＣ、ＦＥＶ＿１、ＦＥＦ＿（２５－７５％）、Ｖ＿（７５）、Ｖ＿（５０）的实测值占预计伍百分比的下降，异常率的增高，与对照组相比，多具有显著的差别；接尘组工人肺功能异常率随接尘工龄延长而递增。多因素分析表明，接尘工龄，吸烟年限是影响肺功能下降的主要因素。     

吸烟对肺功能和末梢血白细胞数的急性影响

本文观察了３１例受试者吸烟对肺功能和末梢血白细胞数的急性影响，结果提示：受试者的ＦＥＶ１、ＰＥＦＲ吸烟后较吸烟前显著下降（Ｐ＜０．０１，Ｐ＜０．０５），而末梢血白细胞数在吸烟后则显著升高（Ｐ＜０．０１）。据此作者认为，吸烟对肺功能的急性影响，主要是导致气道平滑肌的收缩，也可能与气道的炎症反应有关     

丹参对慢性肾功能不全患者心肺功能的影响

用丹参滴注发现ＣＲＩ患者的心脏功能（ＳＶ、ＳＶＩ、ＣＯ、ＣＩ、ＥＦ）较治疗前显著提高（Ｐ〈０．０１￣０．０５），ＴＰＲ较治疗前显著降低（Ｐ〈０．０１），同时还发现肺功能（ＦＶＣ、ＶＣ、ＦＥＶ１）较治疗前显著提高（Ｐ〈０．０１￣０．０５），血气分析中的ＰａＯ２、ＳａＯ２较治疗前显著提高（Ｐ〈０．０１），说明丹参可以提高该类患者的心肺功能。     

多普勒超声心动图评价肺动脉高压病人左心室舒张功能

目的：探讨肺动脉高压（ＰＨ）对左心室舒张功能（ＬＶＤＦ）的影响及其发生机理。方法：用彩色多普勒超声心动图结合右心导管检测观察２８例继发有ＰＨ先心病（ＣＨＤ）病人的ＬＶＤＦ，并与２０例无ＰＨ的ＣＨＤ病人对比分析。结果：继发有ＰＨ的病人二尖瓣口血流频谱Ａ峰流速（ＡＶ）、速度时间积分（ＡＶＩ）较对照组明显增高（Ｐ＜０．０５～０．０１），Ｅ峰流速（ＥＶ）、速度时间积分（ＥＶＩ）无明显改变（Ｐ＞０．０５），ＡＶ／ＥＶ、ＡＶＩ／ＥＶＩ增大（Ｐ＜０．０１），左室等容舒张期（ＬＩＶＲＴ）延长（Ｐ＜０．０５），且肺动脉压与ＡＶ／ＥＶ比值成中等相关（ｒ＝０．４１８９～０．４２４６，Ｐ＜０．０１）。结论：ＰＨ可致ＬＶＤＦ减退，并推测其机理可能与ＰＨ所引起的室间隔运动异常、肥厚、两室间充盈的相互影响及左室三维几何形态的改变等因素有关。     

采用FEV1.0对MVV估计值的推导

本文报告用上消化道癌患者肺功能中的用力呼气第一秒量（ＦＥＶ１．０）与最大通气量（ＭＶＶ）建立由ＦＥＶ１．０去推导ＭＶＶ的直线回归方程。ＦＥＶ１．０与ＭＶＶ的频数分布呈近似正态分布，相关系数（ｒ）为０．７１２６（Ｐ＜０．０１），直线回归方程为ＭＶＶ（１／ｍｉｎ）＝２５．３０９５＋２１．３７×ＦＥＶ１．０（１）。并应用该方程于几种疾病患者对ＭＶＶ估计值的推导，结果显示ＭＶＶ的实测值与推导值之间存在高度正相关性（Ｐ＜０．０１），认为应用该方程于临床测定是可信的。     

雾化吸入博利康尼治疗哮喘患儿78例肺功能观察

应用博利康尼雾化溶液对７８例急性期哮喘患儿进行雾化吸入,并在雾化前、后作肺功能的测定和指标比较,结果显示,雾化前、后肺通气功能指标： ＦＥＦ２５、 ＦＥＦ５０、 ＦＥＦ７５、ＭＭＥＦ７５／２５均较吸入前差异有非常显著性（Ｐ＜０．０１）,ＰＥＦ差异有显著性（Ｐ＜０．０５）。雾化前、后肺力学指标：Ｒ５、Ｒ２０、Ｒ５－Ｒ２０、Ｘ５均较吸入前明显减低（Ｐ＜０．０１）。提示雾化吸入博利康尼雾化溶液治疗儿童哮喘急性发作可缓解临床症状,并改善肺功能。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.