Medical image diagnosis of liver cancer by feedback GMDH-type neural network using knowledge base

A revised group method of data handling (GMDH)-type neural network algorithm using knowledge base for medical image diagnosis, is proposed and applied to medical image diagnosis of liver cancer. In this algorithm, the knowledge base for medical image diagnosis is used for organizing the neural network architecture for medical image diagnosis. Furthermore, the revised GMDH-type neural network algorithm has a feedback loop and can identify the characteristics of the medical images accurately using feedback loop calculations. It is shown that the revised GMDH-type neural network is accurate and a useful method for the medical image diagnosis of the liver cancer.     

Feedback GMDH-type neural network algorithm and its application to medical image analysis of cancer of the liver

A revised group method of data handling (GMDH)-type neural network algorithm for medical image recognition is proposed, and is applied to medical image analysis of cancer of the liver. The revised GMDH-type neural network algorithm has a feedback loop and can identify the characteristics of the medical images accurately using feedback-loop calculations. In this algorithm, the polynomial type and the radial basis function (RBF)-type neurons are used for organizing the neural network architecture. The optimum neural network architecture fitting the complexity of the medical images is automatically organized so as to minimize the prediction error criterion, defined as the prediction sum of squares (PSS).     

Deep multi-layered GMDH-type neural network using revised heuristic self-organization and its application to medical image diagnosis of liver cancer

In this study, the deep multi-layered group method of data handling (GMDH)-type neural network algorithm using revised heuristic self-organization method is proposed and applied to medical image diagnosis of liver cancer. The deep GMDH-type neural network can automatically organize the deep neural network architecture which has many hidden layers. The structural parameters such as the number of hidden layers, the number of neurons in hidden layers and useful input variables are automatically selected to minimize prediction error criterion defined as Akaike’s information criterion (AIC) or prediction sum of squares (PSS). The architecture of the deep neural network is automatically organized using the revised heuristic self-organization method which is a type of the evolutionary computation. This new neural network algorithm is applied to the medical image diagnosis of the liver cancer and the recognition results are compared with the conventional 3-layered sigmoid function neural network.     

Medical image diagnosis of lung cancer by multi-layered GMDH-type neural network self-selecting functions

In this study, a revised Group Method of Data Handling (GMDH)-type neural network self-selecting functions is applied to the computer aided image diagnosis (CAD) of lung cancer. The GMDH-type neural network algorithm has an ability of self-selecting optimum neural network architecture from three neural network architectures, such as sigmoid function neural network, radial basis function neural network and polynomial neural network. The GMDH-type neural network also has abilities of self-selecting the number of layers, the number of neurons in hidden layers and useful input variables. This algorithm is applied to CAD of lung cancers, and it is shown that this algorithm is useful for the CAD, and is very easy to apply to practical complex problems because optimum neural network architecture is automatically organized.     

Three-dimensional medical image analysis of the heart by the revised GMDH-type neural network self-selecting optimum neural network architecture

In this study, a revised group method of data handling (GMDH)-type neural network algorithm which self-selects the optimum neural network architecture is applied to 3-dimensional medical image analysis of the heart. The GMDH-type neural network can automatically organize the neural network architecture by using the heuristic self-organization method, which is the basic theory of the GMDH algorism. The heuristic self-organization method is a kind of evolutionary computation method. In this revised GMDH-type neural network algorithm, the optimum neural network architecture was automatically organized using the polynomial and sigmoid function neurons. Furthermore, the structural parameters, such as the number of layers, the number of neurons in the hidden layers, and the useful input variables, are selected automatically in order to minimize the prediction error criterion, defined as the prediction sum of squares (PSS).     

Medical image analysis of abdominal X-ray CT images by deep multi-layered GMDH-type neural network

In this study, a deep multi-layered group method of data handling (GMDH)-type neural network is applied to the medical image analysis of the abdominal X-ray computed tomography (CT) images. The deep neural network architecture which has many hidden layers are automatically organized using the deep multi-layered GMDH-type neural network algorithm so as to minimize the prediction error criterion defined as Akaike’s information criterion (AIC) or prediction sum of squares (PSS). The characteristics of the medical images are very complex and therefore the deep neural network architecture is very useful for the medical image diagnosis and medical image recognition. In this study, it is shown that this deep multi-layered GMDH-type neural network is useful for the medical image analysis of abdominal X-ray CT images.     

Medical image diagnosis of kidney regions by deep feedback GMDH-type neural network using principal component-regression analysis

The deep feedback Group Method of Data Handling (GMDH)-type neural network is applied to the medical image recognition of kidney regions. In this algorithm, the principal component-regression analysis is used for the learning calculation of the neural network, and the accurate and stable predicted values are obtained. The neural network architecture is automatically organized so as to fit the complexity of the medical images using the prediction error criterion defined as Akaike’s Information Criterion (AIC) or Prediction Sum of Squares (PSS). The recognition results show that the deep feedback GMDH-type neural network algorithm is useful for the medical image recognition of kidney regions, because the optimum neural network architecture is automatically organized.     

Deep feedback GMDH-type neural network and its application to medical image analysis of MRI brain images

The deep feedback group method of data handling (GMDH)-type neural network is applied to the medical image analysis of MRI brain images. In this algorithm, the complexity of the neural network is increased gradually using the feedback loop calculations. The deep neural network architecture is automatically organized so as to fit the complexity of the medical images using the prediction error criterion defined as Akaike’s information criterion (AIC) or prediction sum of squares (PSS). The recognition results show that the deep feedback GMDH-type neural network algorithm is useful for the medical image analysis of MRI brain images, because the optimum neural network architectures fitting the complexity of the medical images are automatically organized so as to minimize the prediction error criterion defined as AIC or PSS.     

Revised GMDH-type neural network algorithm self-selecting optimum neural network architecture

In this study, the revised group method of data handling (GMDH)-type neural network (NN) algorithm self-selecting the optimum neural network architecture is applied to the identification of a nonlinear system. In this algorithm, the optimum neural network architecture is automatically organized using two kinds of neuron architecture, such as the polynomial- and sigmoid function-type neurons. Many combinations of the input variables, in which the high order effects of the input variables are contained, are generated using the polynomial-type neurons, and useful combinations are selected using the prediction sum of squares (PSS) criterion. These calculations are iterated, and the multilayered architecture is organized. Furthermore, the structural parameters, such as the number of layers, the number of neurons in the hidden layers, and the useful input variables, are automatically selected in order to minimize the prediction error criterion defined as PSS.     

Multi-objective evolutionary optimization of polynomial neural networks for modelling and prediction of explosive cutting process

In this paper, evolutionary algorithms (EAs) are deployed for multi-objective Pareto optimal design of group method of data handling (GMDH)-type neural networks which have been used for modelling an explosive cutting process using some input–output experimental data. In this way, multi-objective EAs (non-dominated sorting genetic algorithm, NSGA-II) with a new diversity-preserving mechanism are used for Pareto optimization of such GMDH-type neural networks. The important conflicting objectives of GMDH-type neural networks that are considered in this work are, namely, training error (TE), prediction error (PE), and number of neurons (N) of such neural networks. Different pairs of theses objective functions are selected for 2-objective optimization processes. Therefore, optimal Pareto fronts of such models are obtained in each case which exhibit the trade-off between the corresponding pair of conflicting objectives and, thus, provide different non-dominated optimal choices of GMDH-type neural networks models for explosive cutting process. Moreover, all the three objectives are considered in a 3-objective optimization process, which consequently leads to some more non-dominated choices of GMDH-type models representing the trade-offs among the training error, prediction error, and number of neurons (complexity of network), simultaneously. The overlay graphs of these Pareto fronts also reveal that the 3-objective results include those of the 2-objective results and, thus, provide more optimal choices for the multi-objective design of GMDH-type neural networks in terms of minimum training error, minimum prediction error, and minimum complexity.     

Three-dimensional medical image recognition of cancer of the liver by a revised radial basis function (RBF) neural network algorithm

In this study, we propose a revised radial basis function (RBF) neural network algorithm and apply this algorithm to computer-aided diagnosis (CAD) of the liver. First, the revised RBF neural network algorithm is applied to recognition of the liver regions, and the recognition results are compared with those obtained using the conventional RBF neural network and the conventional multilayered neural network trained using the back-propagation algorithm. It is shown that the revised RBF neural network is accurate, and is a useful method because the parameters are automatically determined. Then, the revised RBF neural network is applied to CAD of the liver cancer called hepatocellular carcinoma (HCC).     

基于神经网络集成的肺癌早期诊断

将病理性诊断与计算机技术相结合以实现肺癌的早期诊断，首先利用数字图像技术对肺癌穿刺样本进行处理，提出取形态和色度特征，然后通过一种二级集成结构和特殊的投票方式，用神经网络集成对细胞图象进行分析，实验和原型系统试用表明，方法的总误诊率和肺癌患者漏诊率均低于单一神经网络方法和常用的神经网络集成方法。     

肺癌分类识别中的神经网络集成技术研究

This paper describes a neural network ensemble method in lung cancer cell identification process. A neural network ensemble algorithm LCNE based on image feature extraction is proposed. Firstly, LCNE algorithm trains different neural network classifiers designed for shape and color features individually. Then, using neural network en-semble method, the final lung cancer cell identification results can be achieved. On the basis of LCNE algorithm, weimplement a lunu cancer cell identification system LCDS successfully.     

基于神经网络架构搜索的肺结节分类算法

肺结节分类是早期肺癌诊断的重要任务。基于深度学习的肺结节分类方法虽然能够取得良好的分类精度,但存在模型复杂和可解释性差的问题。为此,提出了一种基于神经网络架构搜索的肺结节分类算法。首先,将注意力残差卷积cell作为搜索空间的基本单元,并使用偏序剪枝方法作为搜索策略来构建神经网络架构以搜索3D分类网络,从而达到网络性能和搜索速度的平衡。其次,在网络中构建了多尺度通道和空间注意力模块来提高特征描述和类别推理的可解释性。最后,采用堆叠法将搜索到的网络架构进行多模型的融合,从而获取精准的肺结节良恶性分类预测结果。实验结果表明,在肺结节分类常用数据集LIDC-IDRI上,所提算法与最新肺结节分类算法相比具有较好的分类性能和较快的收敛,且所提算法的特异性和精确率分别达到95.37%和93.42%,能够实现良恶性肺结节的准确分类。     

基于BP神经网络的医学图像分割新方法

对于医学图像而言,其分割结果的准确性对医生诊断病情并给出正确的治疗方案至关重要。应用传统的BP神经网络对医学图像进行分割,存在对初始权重值敏感、学习速率固定、收敛速度慢和易陷入局部极小值等问题。因此,提出了一种基于改进的粒子群优化算法的BP 神经网络的医学图像分割方法。首先,应用粒子群优化算法与BP神经网络的映射关系,通过粒子群强大的搜索功能找到最佳适应函数,使对应的BP神经网络的均方误差达到最小值,克服了BP 神经网络产生多个局部最小值的可能;其次,确定粒子的最佳位置后,在BP神经网络学习中获得最合理的权值和偏置值,以提高网络的收敛速度;最后,BP神经网络经反复训练后,获得最佳输出值,并计算阈值,通过阈值来分割图像区域。实验结果表明,利用改进的算法能够得到更清晰的图像分割效果,提高了图像的分割精度,对临床的诊断也具有重要参考意义。     

基于小波神经网络的医学图像分类方法

为了提高乳腺癌早期诊断的准确率,将小波理论与神经网络理论相结合提出改进的小波神经网络算法。将经过预处理的医学图像提取特征值,然后利用基于改进的小波神经网络算法的分类器对医学图像进行分类。通过实验表明此分类器具有较高的分类精度,是有效和可行的;与单独使用后向传播神经网络算法相比分类效果也得到了改善。     

卷积神经网络在肝癌病理图像诊断中的应用综述

肝癌是一种恶性肝肿瘤,起源于肝细胞.肝癌诊断一直是医学难点问题,也是各领域研究的热点问题,早期确诊肝癌可以降低肝癌的死亡率.组织病理学图像检查是肿瘤学诊断的黄金标准,图像会显示组织切片的细胞和组织结构,可以用于确定细胞类型、组织结构、异常细胞的数量和形态,并评估肿瘤具体情况.本文重点研究了卷积神经网络针对病理图像的肝癌诊断算法,包括肝肿瘤检测、图像分割以及术前预测这3个方面的应用,详细阐述了卷积神经网络各算法的设计思路和相关改进目的及方法,以便为研究人员提供更清晰的参考思路.总结性分析了卷积神经网络算法在诊断中的优缺点,并对未来可能的研究热点和相关难点进行了探讨.     

癌细胞显微图像分割与识别研究

文章采用竞争Hopfield神经网络的自动聚类分割方法从腹水脱落细胞显微图像中分割可疑细胞和可疑细胞核,提取癌细胞的15个形态特征,利用柔性BP神经网络分类器对腹水脱落癌细胞进行分类识别。通过对临床病例的检验分析,表明该方法能获得较高的诊断正确率。     

医学图像自动分割的神经网络算法

提出了一种基于Ｋｏｈｏｎｅｎ聚类神经网络的图像分割算法。首先论述了Ｋｏｈｏｎｅｎ聚类神经网络的基本原理，在此基础上对其进行了改进，将其用于医学图像分割中。针对聚类中心初始值选取的盲目性，提出了初始值优选法，大幅度提高了分割算法的速度。实验表明，本文提出的算法能快速、准确地完成医学图像的自动分割。     

一种基于PCA/SOFM混合神经网络的图象压缩算法

鉴于用神经网络实现图象压缩是一种非常有效的方法,为此提出了一种基于PCA/SOFM混合神经网络的图象压缩编码算法,并对SOFM网络学习参数的优化进行了探讨.实验证明,与PCA SOFM连续编码算法和基本SOFM算法相比,这种混合编码算法,由于占用存储空间少,因而降低了码书设计的计算量,并改善了码书的性能.