经皮子宫动脉拴塞治疗产后出血围手术期观察与护理

目的:总结产后出血介入治疗围手术期观察与护理的体会。方法:对30例产后出血应用介入治疗的产妇在围手术期的观察与护理进行回顾总结。结果:30例产后出血应用介入治疗的产妇除1例切除子宫外,其余均迅速止血。结论:产后出血介入治疗是安全有效的疗法,围手术期护理是保障手术成功的关键之一。     

介入治疗在难治性产后出血中的临床探讨

目的探讨介入治疗在难治性产后出血中的应用价值。方法采用双侧髂内动脉栓塞术治疗难治性产后出血患者20例,观察其临床效果。结果 20例患者介入治疗均有效,成功保留了子宫。结论介入治疗难治性产后出血效果好,创伤小,无明显并发症,可重复使用,是值得重视的治疗方法。     

介入治疗在产后出血中的应用

目的 探讨介入治疗在产后出血中的疗效以及评估其临床意义.方法 回顾性分析我院在2008年10月～2010年3月期间9例采用介入疗法治疗产后出血的病例,9例产后出血患者均采用Seldinger技术穿刺股动脉,行子宫动脉造影,并应用明胶海绵栓塞子宫动脉.结果 9例产后出血患者采用传统疗法均不能有效控制出血,采用介入疗法后能够有效地控制出血,纠正患者休克状态,并且介入治疗具有时间短,止血快,能够保留子宫等功能.术后9例患者无一例发生下肢动脉血栓形成.结论 介入治疗能够控制传统疗法所不能控制的严重产后出血,提高产妇发生严重产后出血的生存率,为临床应用介入疗法治疗产后出血提供了有力依据.     

介入治疗产后出血的护理

目的 探讨介入栓塞治疗产后出血患者的护理.方法 对10例产后出血患者应用介入栓塞治疗,术前做好心理护理,完善术前准备,积极纠正休克,术后加强观察护理,预防并发症的发生.结果 10例产后出血患者,9例介入治疗成功,无并发症发生.1例介入治疗失败,改行子宫切除手术.结论 产后出血行介入栓塞治疗是治疗产后出血的有效方法,但严密的病情观察、合理有效的护理是介入栓塞治疗产后出血成功的一个重要保证.     

介入治疗瘢痕子宫引产后出血的护理

目的探讨介入栓塞治疗瘢痕子宫引产后出血患者的护理。方法对15例瘢痕子宫引产后出血患者应用介入栓塞治疗,术前做好心理护理,完善术前准备,积极纠正休克,术后加强观察护理,预防并发症的发生。结果 15例瘢痕子宫引产后出血患者,14例介入治疗成功,无并发症发生。1例介入治疗失败,改为子宫切除手术。结论瘢痕子宫引产后出血行介入栓塞治疗是治疗产后出血的有效方法,但严密的病情观察、合理有效的护理是介入栓塞治疗产后出血成功的一个重要保证。     

晚期产后出血9例介入治疗分析

目的:探讨放射性介入治疗晚期产后出血的临床意义。方法:对9例晚期产后出血患者采用Seldinger技术穿刺股动脉,行超选择子宫动脉造影,并应用明胶海绵栓塞子宫动脉。结果:9例患者栓塞均一次成功,介入治疗后阴道出血基本消失,1例仅有少许血性分泌物;术后出现发热2例,坐骨神经痛4例,均自行缓解。结论:介入治疗应用于晚期产后出血具有止血快,疗效确切,手术时间短,并发症少等优点。     

介入治疗在产后出血中的应用

目的探讨介入治疗在产后出血中的应用价值。方法将3家医院产后出血保守治疗无效行次全子宫切除或全子宫切除术50例为手术组,行介入治疗10例为介入组。结果介入组手术时间57·5min,明显短于手术组122·5min(P<0·05);介入组栓塞后止血时间为(6·0±2·8)min,手术组1例行次全子宫切除后出血转用介入治疗成功止血,余均止血成功。结论介入治疗应用于产后出血具有止血确切、手术时间短、并发症少的优点。     

介入治疗在产后出血中的应用

目的 探讨介入治疗产后出血的临床效果.方法 收集我院介入治疗经保守治疗无效的5例产后出血病例完整病历,分析止血效果,并发症及注意事项.结果 5例均获有效止血,有效率100%,发热和疼痛是最常见的并发症.结论 介入治疗是一种安全有效的产后出血止血方法.     

介入治疗晚期产后出血3例临床分析

目的:探讨介入治疗晚期产后出血的临床疗效。结论:介入治疗晚期产后出血是一种快速显效的微创手段。     

产后出血介入治疗的护理体会

目的：探讨介入栓塞治疗产后出血患者的护理。方法：对20例应用介入栓塞治疗患者术前做好心理护理，积极纠正休克；术中密切配合，备好急救药品、器材；术后做好基础护理，预防并发症的发生。结果：20例产后出血患者，1例介入治疗失败，其他全部介入治疗成功。结论：产后出血行介入栓塞治疗是治疗产后出血的有效方法，但严密的病情观察、合理有效的护理是介入栓塞治疗产后出血成功的一个重要保证。     

Coronary arteriovenous fistula with giant aneurysm formation treated with percutaneous intervention

Coronary arteriovenous fistula （CAVF） is an uncommon anomaly, occurring 0.1% to 0.2% atcoronary angiography. Although majority of CAVF are small and silent, they may cause fistula-related complications, especially in the elderly patients. Therapeutic strategies for CAVF have not been clearly defined because of uncertainty of its natural history. Surgical repair for CAVF is generally recommended in the presence of symptoms of heart failure or significant left-to-right shunt. Various devices have been used during interventional treatment of CAVF through percutaneous approach.3 In this study, we report a rare female case of coronary-pulmonary artery fistula concomitant with a giant saccular coronary artery aneurysm, arising from the left anterior descending artery and draining into pulmonary artery. It was eventually closed by percutaneous intervention with coils.     

Association between intervertebral disc degeneration and disturbances of blood supply to the vertebrae

Low back pain is a common public health problem in western industrialized societies and the world as well.Studies indicate that the prevalence rate ranges to 35%, with around 10% of patients from 12% becoming chronically disabled. It also places an enormous economic burden on society. Although the exact cause of low back pain has yet to be defined, intervertebral disc degeneration is considered a major source of it. Since patients with degenerative discs are often asymptomatic, the mechanisms of it are still unclear.     

Relevance of muscle biopsy for diagnosing multifocal motor neuropathy

Multifocal motor neuropathy （MMN） is a rare,.focal,inflammatory,demyelinating disease of the peripheral nerves with pure motor involvementJ MMN is clinically characterized by slowly progressive,asymmetric,distal,upper limb predominant weakness,in the absence of sensory disturbances） Weakness is usually multifocal and connected to a distinct motor nerve,such as the musculocutaneous nerve resulting in biceps weakness,the posterior interosseus nerve resulting in finger drop,the median,ulnar,or radial nerve resulting in dexterity problems or grip weakness,or the peroneal nerve resulting in a foot drop.Onset of clinical manifestations is between 20 and 50 years of age.The prevalence of MMN is reported as 1-2 per 100 000.2 MMN is three times more frequent in men as compared to women.     

Saffron （Crocus sativus L.） and major depressive disorder： a meta-analysis of randomized clinical trials

Due to safety concerns and side effects of many antidepressant medications, herbal psychopharmacology research has increased, and herbal remedies are becoming increasingly popular as alternatives to prescribed medications for the treatment of major depressive disorder （MDD）. Of these, accumulating trials reveal positive effects of the spice saffron （Crocus sativus L.） for the treatment of depression. A comprehensive and statistical review of the clinical trials examining the effects of saffron for treatment of MDD is warranted. OBJECTIVE： The purpose of this study was to conduct a meta-analysis of published randomized controlled trials examining the effects of saffron supplementation on symptoms of depression among participants with MDD. SEARCH STRATEGY： We conducted electronic and non-electronic searches to identify all relevant randomized, double-blind controlled trials. Reference lists of all retrieved articles were searched for relevant studies. INCLUSION CRITERIA： The criteria for study selection included the following： （1） adults （aged 18 and older） with symptoms of depression, （2） randomized controlled trial, （3） effects of saffron supplementation on depressive symptoms examined, and （4） study had either a placebo control or antidepressant comparison group. DATA EXTRACTION AND ANALYSIS： Using random effects modeling procedures, we calculated weighted mean effect sizes separately for the saffron supplementation vs placebo control groups, and for the saffron supplementation vs antidepressant groups. The methodological quality of all studies was assessed using the Jadad score. The computer software Comprehensive Meta- analysis 2 was used to analyze the data. RESULTS： Based on our pre-specified criteria, five randomized controlled trials （n = 2 placebo controlled trials, n = 3 antidepressant controlled trials） were included in our review. A large effect size was found for saffron supplementation vs placebo control in treating depressive symptoms （M ES = 1.62, P 〈 0.001）, revealing that saffron supplementation significantly reduced depression symptoms compared to the placebo control. A null effect size was evidenced between saffron supplementation and the antidepressant groups （M ES = -0.15） indicating that both treatments were similarly effective in reducing depression symptoms. The mean Jadad score was 5 indicating high quality of trials. CONCLUSION： Findings from clinical trials conducted to date indicate that saffron supplementation can improve symptoms of depression in adults with MDD. Larger clinical trials, conducted by research teams outside of Iran, with long-term follow-ups are needed before firm conclusions can be made regarding saffron＇s efficacy and safety for treating depressive symptoms.     

痘苗病毒天坛株的减毒与其作为疫苗载体研究进展

1痘苗病毒天坛株的历史天花是人类历史上最可怕的传染病之一。天花由天花病毒（variola virus）引起,人是该病毒的惟一宿主。人感染天花病毒后的死亡率达到30%~40%[1]。世界上公认的对天花最早的准确记录来自中国,晋代药学家葛洪于公元430年左右,在《肘后备急方》中对天花有清楚的描述[1]。     

WHO西太区与世界中医药学会联合会中医名词术语国际标准比较研究：八纲辨证（三）

The Chinese characters 寒 and 热, 虚, and 实 are quite common concepts in Chinese language. However in traditional Chinese medicine （TCM）, they are used as four principles in syndrome differentiation. In terms of translation, 寒 and 热 are very easy to understand and can be simply translated as ＂cold＂ and ＂heat＂. But the transla- tion of 虚 and 实 used to be a problem. For a quite long time in translation practice,     

Gene expression profiles of ERCC1, TYMS, RRM1, TUBB3 and EGFR in tumor tissue from non-small cell lung cancer patients

Background Personalized medicine becomes essential in lung cancer treatment, however lung-cancer-related gene expression profiles in Chinese patients remain unknown. In this study, the correlation of gene expression profiles and clinical characteristics in non-small-cell lung cancer （NSCLC） was investigated. Methods Seventy-six Chinese patients with NSCLC were enrolled in the study to investigate mRNA expression profiles of excision repair cross complement group 1 （ERCC1）, thymidylate synthetase （TYMS）, ribonucleotide reductase （RRM1）, class Ill 13-tubulin （TUBB3）, and epidermal growth factor receptor （EGFR） genes and their correlation with patient clinical characteristics. A novel liquidchip technology was used to detect mRNA expression levels in formalin fixed paraffin embedded tumor pathology samples. The relationships between gene expression and clinical characteristics were assessed using the Mann-Whitney test. Results ERCC1 mRNA levels were higher in tumors from patients with metastatic disease than patients with non- metastatic disease （P=-0.021）, and higher in adenocarcinomas than squamous cell carcinomas （P=0.006）. Increased TUBB3 mRNA expression levels were found in patients with performance status （PS） 1 in comparison with PS 0 （P=0.049）, with poorly differentiated tumors in comparison with tumors that were moderately and well differentiated （P 〈0.000 1）, and with advanced stage in comparison with early stage disease （P 〈0.000 1）. Conclusions ERCC1 mRNA levels were higher in metastatic adenocarcinoma NSCLC; TUBB3 mRNA levels were significantly higher in poorly differentiated tumors and in advanced stage NSCLC, which indicates the poor prognosis.     

高维列联表资料的统计分析与SAS软件实现（六）

非条件logistic回归分析方法的主要算法是采用最大似然法对参数进行估计。最大似然法在大样本前提下进行参数估计是非常有效的,但当处理样本量小的数据,特别是按多个定性变量进行分层且每一层中样本量很小时,