Simultaneous reconstruction of columella and philtrum using prolabial flap combined with Abbe flap in secondary bilateral cleft lip and nasal deformity

Open rhinoplasty and Abbe flap techniques are traditionally useful tools for the reconstruction of secondary bilateral cleft lip nasal (BCLN) deformity. We aimed to investigate the long-term outcomes of simultaneous columella and philtrum reconstruction using prolabial flap combined with Abbe flap in secondary BCLN deformity.From January 2009 to July 2014, 26 patients (17 males and 9 females; mean age 21 years) with secondary BCLN deformity were recruited. All patients had severe short columella and philtrum deficiency. The whole superiorly based prolabial flap was harvested and trimmed for columella reconstruction. An Abbe flap from the central lower lip was elevated to reconstruct the esthetic philtral unit. No flap necrosis occurred postoperatively. The average follow-up was 2.7 years. The columella length was 4.7 ± 1.3 mm preoperatively and 10.4 ± 2.1 mm postoperatively. The philtrum length increased to 14.4 ± 2.6 mm postoperatively from a preoperative 8.9 ± 2.4 mm. Regarding the overall impression of the reconstruction, 22 patients ranked it as very good or good.In secondary BCLN deformity, the prolabial flap combined with Abbe flap technique is an effective alternative for the treatment of severe short columella complicated with severe philtrum deficiency.     

The central lip flap and nasal mucosal rotation advancement: important aspects of composite correction of the bilateral cleft lip nose deformity

The columella, nasal tip, lip relationship in the secondary bilateral cleft deformity remains an enigma and a great challenge for the cleft surgeon. A subset of patients with bilateral cleft lip still require columellar lengthening and nasal correction, despite the advances in preoperative orthopedics and primary nasal corrections. An approach to correct this deformity is described. This consists of (1) lengthening the columella by a central lip advancement flap; (2) open rhinoplasty, allowing definitive repositioning of lower lateral cartilages, ear cartilage grafting to the tip and columella when necessary; (3) nasal mucosal advancement; (4) alar base narrowing; and (5) reconstruction of the orbicularis oris as required. Depending on the individual assessment of the patients, some of these steps were not performed, leaving the nasal mucosal advancement the most important aspect of the reconstruction. In a consecutive series of 72 patients with repaired bilateral cleft lip and palate, 17 patients have been treated with nasal mucosal rotation advancement and followed up for a maximum period of 10 years. With the use of this technique, the secondary bilateral cleft lip nose deformity has been successfully corrected.     

双侧完全性唇腭裂新生儿进行鼻-齿槽塑形治疗的临床研究

目的观察鼻-齿槽塑形治疗(presurgical nasal-alveolar molding,PNAM)对双侧完全性唇腭裂婴儿的临床疗效。方法对20例出生10天~3个月的双侧完全性唇腭裂新生儿进行鼻-齿槽的整形,测量治疗前后的双侧上唇裂隙宽度、前鼻突到唇裂距离、鼻小柱长度及唇裂交角,并用SPSS21.0软件进行统计分析。结果经过3~4个月的PNAM治疗后,双侧上唇裂隙宽度、前鼻突到唇裂距离明显减小,鼻小柱长度明显增加,均有统计学意义;唇裂交角增大,但无统计学意义。鼻外形左右基本对称,鼻翼外形恢复不明显,鼻小柱位于面部正中位置。结论 PNAM塑形治疗能有效减少双侧完全性唇腭裂婴儿的上唇裂隙宽度,压低前鼻突,伸长鼻小柱,改善鼻外观,降低手术难度。     

鼻唇畸形修复同期行鼻中隔矫正术的疗效评价

目的：探讨鼻唇畸形二期修复同期行鼻中隔偏曲矫正术的手术效果。方法：鼻唇畸形二期修复时做鼻翼缘前庭合并鼻小柱切口，矫正大翼软骨、鼻肌、鼻小柱及鼻中隔的异常解剖位置，离断鼻中隔的异常附着，部分患者去除多余的鼻中隔组织．并将鼻中隔软骨末端可靠固定在正确的位置，与软组织逢合固定，或与前鼻棘等骨性组织缝合固定．同时矫正偏斜的鼻小柱等软组织，通过鼻部软、硬组织的矫正，恢复鼻的正常形态。结果：10例鼻唇畸形二期修复患者随访3个月～1a．通过手术前、后患者的外形和所测数据的比较，认为获得较满意的鼻外形。结论：鼻唇畸形二期修复同期行鼻中隔偏曲矫正术，使患者能够获得较好的鼻外形，并得到保持。     

66例双侧唇裂功能性整复的临床疗效观察

目的 探讨改良Mulliken法功能性修复双侧唇裂的临床效果。方法 选取66例双侧唇裂患者,应用改良Mulliken法进行唇裂整复,术中在前唇设计窄的“领带”型人中结构;解剖复位侧唇口轮匝肌,重建口轮匝肌环;利用侧唇唇红组织重建唇珠。同期初步矫正鼻畸形,延长鼻小柱。结果 术后经0.5~2 a随访,所有患者无“三等份上唇”不良外观,超过80%（54/66）的患者上唇唇弓形态恢复自然,左右对称,人中宽度与正常相似。唇红丰满,唇珠大小适度,无口哨畸形,动静态外形良好。鼻底宽度正常、鼻孔形态对称,鼻小柱高度较术前延长,鼻尖形态基本满意。结论 利用改良Mulliken法功能性修复双侧唇裂,能有效纠正鼻唇畸形,临床效果良好,值得推广使用。     

双侧唇裂术后鼻唇畸形的修复

目的 报道双侧唇裂术后鼻唇畸形修复的一种新方法。方法 在双侧鼻孔的内侧沿鼻小柱皮肤粘膜交界缘向下达鼻小柱基部并经鼻底向外达外侧脚外侧并绕鼻翼外侧脚弧形向上;在上唇正中上部画出叉形瓣切口线;再在双侧鼻孔底部上唇瘤痕两侧画垂线至唇红缘。然后切开鼻底及鼻翼外侧脚皮肤,在鼻翼内侧脚上端缝合。将叉形瓣向上推形成鼻小柱下端。切除上唇瘢痕组织,必要时可设 Abbe瓣经旋转180°后按粘膜、肌层及皮肤层缝合。10～14天行Abbe瓣断蒂。结果 用该术式对34位患者进行了手术,术后鼻唇外形、鼻小柱长度及鼻孔大小趋于正常。上唇过紧得到了松驰。结论 该术式对双侧唇裂术后鼻唇畸形矫正有用。     

Beurteilung von Form und Funktion der Nase nach offener Rhinoplastik bei einseitigen Lippen-Kiefer-Gaumen-Spalten

Secondary septorhinoplasty in patients with cleft lip and palate (CLP) is performed to improve nasal form and function. The purpose of this study was to compare the initial findings and the surgical outcome in 30 patients with unilateral CLP. Open rhinoplasty was carried out to correct nasal deformity. Nasal soft tissue analysis was done by measurement of standardized raster photographs of the nose and lateral teleradiography. Deviations from the ideal form regarding nasal symmetry, nasal width, and alar base line were determined. The nasal profile was assessed by measuring the nasofacial and nasolabial angle, the angle between the upper lip and the Frankfurt horizontal plane (FHP), and the angle between the columella and the FHP. Nasal patency was evaluated by rhinomanometry. The overall flow (cm³/s) was determined and the flow of the cleft side and non-cleft side compared. Evaluations were made immediately before and 6 months after surgery. In the frontal plane, nasal symmetry was significantly improved and the alar form adjusted. The deep position of the columella was corrected. The acute nasofacial angle and the drooping ala were not significantly improved. An increase in the overall flow and correction of the quotient cleft/non-cleft side was achieved by the surgical procedure. In this study, aesthetically and functionally relevant findings were objectified and can be used for quality control.     

自体鼻中隔软骨、耳软骨移植修复单侧唇裂继发鼻畸形

目的:分析单侧唇裂继发鼻畸形的发生机制,观察鼻中隔软骨、耳软骨对单侧唇裂继发鼻畸形的矫治效果,从而探讨理想的修复方法。方法:根据患者的临床特点,选取轻度单侧唇裂继发鼻畸形患者作为研究对象,采用自体鼻中隔软骨、耳软骨二期修复鼻畸形。结果:本组患者共12例,随访时间1～6个月,临床矫治效果良好。结论:鼻中隔软骨、耳软骨移植对轻度唇裂继发鼻畸形具有良好的治疗效果。     

应用保留血管蒂Abbe瓣修复双侧唇裂术后继发畸形的临床研究

目的:探讨应用保留血管蒂Abbe瓣修复双侧唇裂患者术后继发鼻唇畸形的方法及其临床效果。方法:选取双侧唇裂术后继发鼻唇畸形患者10例,由同一医师应用保留血管蒂Abbe瓣对其进行修复,测量术前术后患者鼻唇部的6项指标并分析,评估患者术后的效果及鼻唇部对称性。结果:患者术后均一期愈合,术后人中长度平均增加3.93 mm,人中宽度平均降低3.93 mm,全鼻宽平均降低1.69 mm,有显著统计学差异,上唇对称率达到97.29%,患者术后唇鼻外形恢复良好,接近正常。结论:应用保留血管蒂Abbe瓣修复双侧唇裂术后继发畸形效果良好,可以显著改善唇鼻形态和对称性,适合广泛应用于临床。     

Single-stage repair of secondary unilateral cleft lip-nose deformity in adults

Correction of cleft lip-nose deformity in adult patients is different from that in children. One-stage correction has proved to be a suitable technique for patients with cleft-lip nose deformity. This study aimed to explore a particular single-stage method and evaluate the effect of simultaneous reparation of secondary unilateral cleft lip-nose deformities.Cleft lip patients who had previously undergone nasolabial surgery with residual poor nasal/lip appearance were included. The alveolar bone defect was repaired with granular costal cortical bone. Lip revision and rhinoplasty were performed using diced costal cartilage. The lip, nose, and alveolar deformities were corrected in one stage.From 2011 to 2017, 53 cases were treated. The vermilion discrepancy was corrected in all cases. Fifty-one patients were successfully treated, with primary healing in the bony recipient area. Cancellous bone exposure occurred in two cases. The wounds were healed after debridement and drainage. Appearances were improved in all patients. The mean change in columella–labial angle ranged from 82.50 to 92.78° (p < 0.001).This one-stage correction appears to have led to a distinct improvement in the nasal tip projection and lip. The method is considered to be effective and reliable in patients with secondary unilateral cleft lip-nose deformities.     

Improved nasal tip projection in the treatment of bilateral cleft nasal deformity

The cleft nose deformity in bilateral cleft lip and palate patients with severely flattened alar cartilages, a short, scarred columella, and thickened skin is a reconstructive challenge. The Wolfe double-arch tip rhinoplasty technique was compared with a cartilage release and tip grafting technique to determine the optimal modality for tip projection and columella lengthening. Patients with significant bilateral cleft nasal deformities and previous bilateral cleft lip repairs were divided into two groups (n = 22). Group 1 (double-arch) patients underwent an open rhinoplasty using conchal cartilage grafts to create a columellar strut and new lower lateral arches placed over the existing arches (n = 12). In group 2 (release and tip graft), the lower lateral cartilages were released, and nasal tip grafting was performed (n = 10). Preoperative and 6-month postoperative measurements, including (1) columellar length, (2) alar base-nasal tip-columellar base (ATC) angle, and (3) lateral tip projection, were compared. The lateral tip projection is the perpendicular distance between the nasal tip and a line created from the connection of points at the nasion to the subnasale. In group 1 (double arch), the mean columella length increased 47.2%, whereas in group 2 (release and tip graft), it only increased 14.1%. The ATC angle had a mean decrease or narrowing of 26.7 degrees in group 1, compared with a 12.5 degrees decrease in group 2. Lateral tip projection improvement was greater in group 1 (52.2% increase) compared with group 2 (19.9% increase). The authors' data showed that for the difficult bilateral cleft nasal deformity with significant tip flattening, the double-arch tip rhinoplasty provides improved nasal tip projection.     

两类单侧不全唇裂鼻畸形临床特点的初步研究

目的：研究单侧不全唇裂伴有／和不伴有牙槽突裂患儿的唇、鼻部畸形特征。方法：对68例患者进行唇鼻部相关数据的测量研究,采用改良Mohler术式修复唇裂并同期矫正鼻畸形。结果：术前测量显示伴有牙槽突裂患儿的唇峰～鼻翼,唇峰～鼻小柱基底的距离,鼻孔高,鼻孔宽和鼻小柱高度与不伴有牙槽突裂的患儿相同指标有显著性差异。结论：通过测量数据的分析显示：单侧不完全性唇裂伴有牙槽突裂是一种畸形更为严重的不全唇裂。     

A new modified forked flap with subcutaneous pedicles for adult cases of bilateral cleft lip nasal deformity: from normalization to aesthetic improvement

In adult cases of bilateral cleft lip nasal deformity, an esthetically satisfying result can not be obtained only by manipulation inside the nose with the nasal tip pointing upward. The nasal tip should be made in a more anterior direction for nasal esthetic improvement. Additional tissue beyond the nose is needed, and the forked flap is a useful method in such cases. However, the blood circulation of long and narrow flaps containing the scar, especially after open rhinoplasty, is unstable. We have developed a new long and narrow forked flap that has a more stable blood circulation. The forked flap was made using two subcutaneous pedicles attached to the periphery of the each flap. We applied this flap to five adult cases of bilateral cleft lip nasal deformity. Four of the cases had the scar associated with the flying bird incision, and one case required no treatment after the primary repair. All the flaps took without signs of partial necrosis. In all cases, the nasal tip was projected forward with adequate columella elongation, and the profile was esthetically improved. In the final stage of correction for adult cases of bilateral cleft lip nasal deformity, this method, making maximum use of the tissue containing the scar in not only the white lip but also the vermilion, is very effective. It is very important to obtain nasal esthetic improvement for the adult patient with bilateral cleft lip nasal deformity.     

Secondary correction of nasal abnormalities associated with cleft lip.

Approximately 30% of patients will require a second operation for correction of nasal abnormalities associated with unilateral cleft lip. In a single second operation, the following steps seem to give the most satisfactory correction: repositioning the nasal septum in the midline; altering the contour of the alar cartilage on the cleft side; and rotation of the axis of the external naris on the cleft side. The usual result following this combination of procedures is moderate but not complete correction of the abnormality. About 50% of the patients will need a second operation for correction of nasal abnormalities associated with bilateral cleft lip. Satisfactory correction of the bilateral cleft lip nasal deformity is usually obtained by lengthening the columella (which secondarily corrects a flat nasal tip) and narrowing the width of the nose at the level of the alae. Satisfactory restoration to normal is usually obtained by the aforementioned procedure.     

Repair of bilateral complete cleft lip and nasal deformity--state of the art.

OBJECTIVE: Dissatisfaction with the stigmata of repaired bilateral cleft lip has stimulated surgeons to change conventional operative strategies. The old staged labial repairs, one side and later the other, have been replaced by simultaneous closure. For nasal correction, most surgeons no longer believe that the columella is deficient, and thus there is no need to recruit tissue from the lip or nostril sills as a secondary procedure. The columella is concealed in the nose. The new strategy is to construct the columella and nasal tip by anatomic positioning of the alar cartilages and sculpting the investing skin. Furthermore, nasal correction is done at the time of bilateral labial repair and, whenever possible, the alveolar clefts are closed as well. The goal is primary repair of the primary palate. CONCLUSION: Although the principles of synchronous repair of the bilateral complete cleft lip and nasal deformity are established, the techniques continue to evolve. Bilateral nasolabial repair requires continual study of three-dimensional form and fourth-dimensional changes that are normal and altered by the deformity. Every surgeon who lifts a knife to care for these children has an obligation to periodically assess outcome.     

Construction of the congenitally missing columella in midline clefts.

BACKGROUND: Repair of the rare median cleft lip occurring with agenesis of the columella is a challenge as there is a major deficiency of skin and underlying structures. MATERIAL AND METHODS: Over a 23- year period, five children underwent construction of a columella. A new surgical technique was designed for this: an internal dorsal nasal flap was used to create a cutaneous-cartilaginous flap inside the nasal dome, and was then sutured inferiorly against a superior triangle of the repaired median cleft lip. RESULTS: Projective nasal growth could be seen in three of the five surgically constructed columellae in whom the medium-term results could be evaluated. CONCLUSION: Five holoprosencephaly cases, all with a median cleft lip and agenesis of the columella, underwent a median cleft lip repair and the creation of a columella by means of an internal nasal dorsal skin flap procedure.     

Three-dimensional nasal changes following nasoalveolar molding in patients with unilateral cleft lip and palate: geometric morphometrics.

OBJECTIVE: To evaluate three-dimensional changes in nasal morphology in patients with unilateral cleft lip and palate treated with presurgical nasoalveolar molding (NAM) to correct naso-labio-alveolar deformity. DESIGN: This was a prospective, longitudinal study. Digital stereophotogrammetry was used to capture three-dimensional facial images, and x, y, and z coordinates of 28 nasal landmarks were digitized. SAMPLE: Ten patients with unilateral cleft lip and palate. MAIN OUTCOME MEASURES: Nasal form changes between T1 (age: 28 +/- 2 days, pre-NAM) and T2 (age: 140 +/- 2 days, post-NAM), using conventional measurements and finite-element scaling analysis. RESULTS: Overall nasal changes were statistically different (p < .01), but no linear or curvilinear changes were found. Specifically, relative size increases were found on the noncleft side, involving the upper nose (30%), alar depth (20%), alar dome (30%), columella height (30%), and lateral wall of the nostril (17%). On the cleft side, the following showed a size increase: upper nose (8%), alar dome (5%), columella height (30%), and lateral wall of the nostril (30%). The cleft-side alar curvature, however, showed a large decrease in size (80%), but no changes on the noncleft side were found. Corresponding shape changes and angular changes were also found. CONCLUSIONS: Using NAM, bilateral nasal symmetry in patients with unilateral cleft lip and palate was improved before surgical repair. Furthermore, slight overcorrection of the alar dome on the cleft side using pressure exerted by the nasal stent is indicated to maintain the NAM result.     

牙槽突植骨同期髂软骨移植治疗单侧唇腭裂术后鼻畸形

目的:介绍牙槽突植骨同期髂软骨移植治疗单侧唇腭裂术后鼻畸形的方法。方法:2003年3月～2004年3月,12例单侧唇腭裂术后严重鼻畸形患者在牙槽突植骨术的同时行鼻成形术,并切取部分髂软骨雕刻成"L"形,作为隆鼻支架移植于鼻背和鼻小柱处。所有患者术前、术后测量了鼻尖突度、鼻小柱高度、鼻孔横径、鼻孔纵径、鼻小柱偏斜度和鼻唇角,并拍摄面部照片。应用配对 t 检验对数据进行了比较。结果:术后患者鼻孔对称,鼻尖挺拔,鼻外形有了明显改观,术后鼻外形各项数值较术前有显著性差异(P<0.01)。结论:髂软骨移植可为患侧鼻翼软骨提供额外的支持,可用以治疗唇腭裂术后鼻畸形。     

Symmetry of the nose after presurgical nasoalveolar molding in infants with unilateral cleft lip and palate: a preliminary study.

OBJECTIVE: To assess nostril symmetry and alveolar cleft width in infants with unilateral cleft lip and palate following presurgical nasoalveolar molding (NAM). SAMPLE AND METHODS: Fifty-seven newborn patients underwent presurgical nasoalveolar molding. Magnified basal view facial photos were taken at four different times: initial visit (T1), before cheiloplasty (T2), 1 month after cheiloplasty (T3), and 1 year of age (T4). Direct measurements from the photos included: (1) nostril width on the affected and nonaffected side; (2) nostril height on the affected and nonaffected side; (3) columella-nasal base angle; and (4) width of the alveolar cleft. Nostril width and height data were used to calculate a ratio of affected to nonaffected side. RESULTS: Effects of nasal symmetry after presurgical nasoalveolar molding were compared between the affected and nonaffected side. The nostril width ratio was 1.7, 1.2, 1.0, and 1.2 for T1 to T4. The nostril height ratio was 0.5, 0.8, 1.0, and 0.9 for T1 to T4. The angle of the columella was 53.3 degrees , 69.9 degrees , 91.2 degrees , and 86.9 degrees for T1 to T4. The average alveolar cleft width was 8.2 mm at T1 and closed down to 2.4 mm before cheiloplasty (T2) in cases with complete cleft. CONCLUSIONS: Infants with presurgical nasoalveolar molding improved symmetry of the nose in width, height, and columella angle, as compared to their presurgical status. There was some relapse of nostril shape in width (10%), height (20%), and angle of columella (4.7%) at 1 year of age.     

Secondary correction of bilateral cleft lip nose deformity

For correction of the bilateral cleft lip nasal deformity, a modified bilateral reverse U incision is used in combination with a short, forked flap; by using this combination, satisfactory lengthening of the columella, preserving the natural pout of the lip, can be obtained. We have applied this method to 12 cases undergoing secondary repair of bilateral cleft lip in the past 3 years, and the results of this treatment, along with representative photographs of some of our patients, are presented herein.