再生障碍性贫血患者造血干细胞移植后并发播散性带状疱疹1例

患儿女,5岁,右侧腰背部红斑、丘疹、水疱伴疼痛4天,泛发全身1天。患儿11个月前确诊为再生障碍性贫血,9个月前行异基因造血干细胞移植术,术后长期口服环孢素。诊断:(1)播散性带状疱疹;(2)再生障碍性贫血异基因造血干细胞移植术后。     

再生障碍性贫血伴RamsayHunt综合征一例

患者女,55岁,右侧颈部疼痛3天,下颌部出现数片淡红斑2天,随后发生暗红色血疱及坏死,伴右侧头面部疼痛加剧1天而就诊,以带状疱疹收住院.患者自发病以来,精神饮食尚可,二便正常.1997年患再生障碍性贫血,2004年患糖尿病,治疗至今.体检:一般情况好,严重贫血貌,心肺腹未见异常.     

表现为坏疽性脓皮病的原发性抗磷脂综合征猝死一例

患者男，23岁，因面部发疹伴发热3个月，左小腿发疹1个月伴剧痛于2005年8月2日入院。患者丁3个月前无诱因面部出现匠疹、水疱伴有发热，于外院拟Kaposi水痘样疹、血管炎收治．于甲泼尼龙、静脉丙种球蛋白（剂量小详）治疗后好转.出院后患者面部仍反复发疹，1个月前左小腿外伤后出现米粒大小紫红色斑疹，后出现水疱、糜烂，范围逐渐扩大．伴疼痛，为明确诊断来我院就诊。     

5-氨基酮戊酸光动力治疗玫瑰痤疮一例

<正>玫瑰痤疮病因复杂,部分患者由于病程迁延而出现面部红色斑块或鼻赘,使治疗难度加大。我科采用5%5-氨基酮戊酸光动力疗法(ALA-PDT)治疗1例玫瑰痤疮患者,临床效果好,不良反应少,现报告如下。临床资料患者,女,43岁。主因面部红斑、丘疹、脓疱伴瘙痒3月余,于2013年3月就诊。患者3个月前无明显诱因于面部出现散在红斑、丘疹,伴轻度疼痛,偶有瘙痒,逐渐增多。曾口服多种抗组胺药、复方甘草酸苷     

扁平苔藓并发干燥综合征1例

患者女,70岁.因头面部、躯干出现丘疹、斑块伴瘙痒6个月,泛发全身1个月,于2008年3月26日至我科住院治疗.6个月前患者头面部出现米粒大红色丘疹,瘙痒明显,同时伴下唇部肿胀、干裂、渗血和疼痛;2周后胸背部、大腿内侧出现米粒至绿豆大红色丘疹及淡红斑,伴剧烈瘙痒,搔抓后出现许多糠秕状及片状鳞屑,丘疹逐渐变大.     

口服伊曲康唑治疗系统性红斑狼疮合并呼吸道曲霉感染1例

患者，女，40岁。因面部红斑3月伴乏力于2004年2月21日入我院治疗。3个月前面部出现红斑，日晒后加重，伴局部水肿，2个月前全身乏力。同时双手掌及中跖出现红色皮疹，微痛，手足接触冷水无疼痛。     

阿维A治疗不全型毛囊闭锁四联征一例北大核心CSCD

患者男,19岁,以双腋窝、腹股沟、肛周皮疹1年余,加重3个月伴疼痛来我院就诊.患者1年余前无明显诱因肛周出现散在丘疹、硬结,皮疹逐渐扩展至腹股沟及双腋窝,自觉轻度疼痛.近3个月皮疹加重,双腋窝出现散在脓肿、窦道,部分破溃,自觉明显疼痛,遂于2013年3月16日来我院就诊,诊断为聚合性痤疮,门诊予异维A酸胶囊10 mg每日2次、罗红霉素胶囊150mg每日2次口服,2个月后双腋窝、腹股沟、肛周皮疹无明显好转.既往面部、躯干有寻常痤疮病史5年,此次在我院门诊治疗后,面部及躯干的寻常痤疮皮损改善,余无特殊.     

伴有精神症状的SLE2例

例１,女性,１９岁。因四肢关节反复疼痛９个月,面部、趾指末端红斑１个月,诊断为系统性红斑狼疮（ＳＬＥ）,于１９９６年２月入院。患者于１９９５年４月无明显诱因出现四肢关节痛,伴不规则发热。８个月后出现面部蝶形红斑、趾指末端紫红斑。检查：神清,面部蝶形红...     

急性髓细胞性白血病M2a型皮肤浸润一例

患者女,47岁,因面部、四肢皮肤红斑2个月伴间歇发热20余天就诊。患者2个月前出现面颊、颈部红斑,形状不规则,略高于表面,感疼痛不适,不久患者唇部出现散在水疱,伴疼痛,颊部斑块渗出、结痂,颜色渐转暗,边缘呈环状隆起,伴颜面水肿,四肢也逐渐出现红色斑块,20余天前出现发热,体温最高达39 ℃,无畏寒、寒战,无咳嗽咳痰,无胸闷气急……     

中西药结合治疗皮肤垢着病1例

1临床资料患者女,48岁,因"面部秽痂3个月"就诊。患者3个月前于美容院做面膜后面部出现红斑、丘疹,伴瘙痒,自予外用药(具体不详)后面部出现褐色痂垢,皮损面积逐渐增大、增多,伴紧绷感,为避免刺激疼痛,长期未洗脸,痂垢逐渐增多。为求进一步诊治来我科就诊。患者严重焦虑,口干口有异味,大便干,舌红苔黄腻,脉弦滑。     

Photosensitivity associated with treatment with triflusal

BACKGROUND: Triflusal is a fluorinated aspirin derivative with antiplatelet properties, which is used in Spain for the management and prevention of thromboembolic disease. CASE REPORT: A 91-year-old female developed a systemic photosensitivity reaction 15 days after beginning triflusal preventive treatment (300 mg/12 h) for prior transient ischaemic attack. Photobiological study showed an abnormal response to light in areas exposed to ultraviolet B and A radiation, with a photopatch test positive to both triflusal and its main metabolite. These observations suggested a causal relation between triflusal and the clinical findings, as described in previous reports. CONCLUSIONS: The few cases reported to date and the clinicopathological features of this case suggested an immunological response as the most likely cause of the reaction.     

Lymphoma with large-plaque parapsoriasis treated with PUVA

We report on a 78-year-old Japanese woman with a 50-year history of large-plaque parapsoriasis that had evolved into cutaneous T-cell lymphoma. Her large-plaque parapsoriasis had been treated with psoralen plus ultraviolet A for 10 years. Subsequently an isolated nodule appeared on her right lower leg. Prior or concurrent patches or plaques were absent. Histology revealed a diffuse nonepidermotropic infiltrate of large lymphocytes in the dermis, which had enlarged nuclei and prominent nucleoli. A diagnosis of CD30- cutaneous large T-cell lymphoma was made. Following systemic chemotherapy, there was clinical improvement. No evidence of recurrence or systemic lymphoma has subsequently been found.     

糖皮质激素联合免疫球蛋白治疗中毒性表皮坏死松解症15例疗效观察

目的:探讨糖皮质激素联合静脉注射免疫球蛋白(IVIG)治疗中毒性表皮坏死松解症(TEN)的临床疗效、不良反应和转归。方法:回顾性分析15例TEN患者采用糖皮质激素联合免疫球蛋白治疗的临床资料。结果:15例TEN患者均伴有黏膜糜烂,皮损(表皮已剥脱或即将剥脱)面积占体表面积的(19.40±6.51)％;糖皮质激素用量(以泼尼松为标准量):(1.5～2.0)mg/(kg·d);IVIG用量:(0.2～0.4)g/(kg·d),连续用药(6.0±1.3)d。联合用药第(3.0±1.3)天开始起效,痊愈9例,共治疗(23.60±5.49)d;基本痊愈5例,共治疗(16.70±3.14)d;死亡1例。所有患者均可耐受IVIG治疗。结论:糖皮质激素联合IVIG治疗TEN具有协同作用,可明显提高疗效和减少死亡,减少糖皮质激素引起的不良反应。