牵张成骨在颞下颌关节强直及其继发畸形矫治中的应用

儿童时期发生的颞下颌关节强直可以导致不同程度的颌面部骨骼发育障碍,并引起自卑、社交障碍等一系列心理问题,其矫治是口腔颌面外科医生面临的一大挑战. 牵张成骨( distraction osteogenesis,DO)一直被国内外学者用于颞下颌关节(temporomandibular joint,TMJ)强直及其继发畸形的矫治,并取得了良好的临床效果.笔者所在科室每年大概收治50~60例TMJ强直患者,对DO技术在TMJ强直及其继发畸形矫治中的应用积累了较为丰富的临床经验. 本文中,笔者对DO技术在TMJ强直及其继发畸形矫治中的优缺点及相关问题进行述评.     

颌骨牵张成骨术治疗颞下颌关节骨性强直1例

牵引延长骨生成技术(牵张成骨术)应用于颌面外科领域始于20世纪90年代,应用该技术治疗颞下颌关节骨性强直国内仅有少量报道现报告1例。     

牵张成骨术治疗颞下颌关节强直后睡眠呼吸暂停综合征

目的 评估牵张成骨术(DO)治疗颞颌关节强直后睡眠呼吸暂停综合征(OSAS)的效果。方法 对8例患有颞颌关节强直后OSAS的患者采用DO技术进行治疗。手术在全麻下分两期进行。第一期行关节成形、下颌体部截骨,安置牵引器,前徙下颌矫正小颌畸形及OSAS;第二期在拆除第一期牵引器的同时,进行下颌升支后缘L型截骨,安置牵引器,通过牵引延长下颌升支。结果 8例患有颞颌关节强直后OSAS的患者的症状均有不同程度的改善。术后张口度可迭3cm～4cm,小颌畸形得以矫治,AHI指数由术前的20～40降至5以下,最低血氧饱和度由术前的68％提高至术后的96％,OSAS得以治愈。术后半年～两年随访,未见复发。结论 DO技术是治疗颞颌关节强直后OSAS理想方法。     

同期关节重建及下颌体牵张成骨治疗颞下颌关节强直3例报道

目的:对伴有严重牙颌面畸形的颞下颌关节强直患者,采用自体肋骨软骨移植重建关节,同期运用牵张成骨术行下颌骨牵张成骨延长下颌体长度,治疗下颌后缩和阻塞性睡眠呼吸暂停低通气综合征(OSAHS),评价治疗计划的可行性及短期效果。方法:3例颞下颌关节强直患者,平均年龄17.5岁,发生关节强直的平均年龄为3.6岁,病程平均为13.9a,开口度均为0,均伴有严重牙颌面畸形和OSAHS。根据头影测量结果,预先设计患侧下颌支下降的长度和下颌体延长长度;采用关节成形术加双侧冠突切除,术中取模制备板,进行同期自体肋骨软骨移植重建颞下颌关节和双侧下颌体牵张成骨术。术后第7天开始牵引,每天2次,牵引速率为0.8mm/d。结果:3例患者均顺利完成手术,术后未出现感染等严重并发症。顺利完成牵张成骨。下颌骨牵引长度平均为22.5mm(20.5～25mm)。术后3个月开口度平均为28mm(26～32mm),患者面形及OSAHS获得良好改善。结论:肋骨软骨移植关节重建同期进行下颌体牵张成骨具有良好的稳定性,该设计有利于缩短治疗周期和治疗费用,在短期内可同时解决开口、面形和OSAHS等问题,为后续矫正咬合关系奠定了基础。     

儿童颞下颌关节强直及其继发畸形的矫治

目的: 探讨儿童颞下颌关节强直及其继发畸形的治疗方法及疗效。方法: 回顾分析18例颞下颌关节强直继发牙颌面畸形患儿的临床资料,对患儿手术前后口腔功能、颜面外形及影像学资料进行分析,随访12~40月。结果: 所有患儿均实施重建髁突的关节成形术,重建材料包括肋骨肋软骨移植、冠突移植及牵张成骨术,并同时进行牙颌面畸形的矫治。未发现感染、面神经损伤和复发病例。所有患儿的术后张口度明显增大(术前平均2.83 mm,术后12月平均30.5 mm,Z=3.733,P<0.05),咀嚼、吞咽、发音和呼吸等口腔功能在长期随访期间得到明显改善。多数患儿的牙颌面畸形得到不同程度的改善。结论: 本研究为儿童颞下颌关节强直继发牙颌面畸形的治疗提供参考,早期治疗和定期复查对于儿童颞下颌关节强直及其继发畸形的治疗至关重要。     

联合运用牵张成骨及颏成形术矫治颞下颌关节强直继发小下颌畸形伴OSAHS

目的:探讨联合运用牵张成骨及颏成形术配合正畸治疗矫治颞下颌关节强直继发小下颌畸形伴阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的可行性.方法:9例双侧关节强直继发小下颌畸形伴OSAHS患者,一期通过关节成形术解除关节强直,完成正畸治疗后,二期运用牵张成骨及颏成形术矫治小下颌畸形伴OSAHS,随访8～36月,评价其治疗效果.结果:患者平均张口度由术前3.1mm提高到术后36.5 mm,小下颌畸形得到有效治疗,OSAHS得到同期治愈.结论:联合运用牵张成骨及颏成形术并配合正畸治疗,是矫治关节强直继发小下颌畸形伴OSAHS的有效治疗方案.     

牵张成骨术矫正单侧真性关节强直偏颌畸形1例

对1例因关节强直导致的偏颌畸形患者行下颌骨体牵张成骨器植入术,术后1周开始牵张右侧下颌骨,牵张20 d后右侧下颌升支及下颌体高度明显增加,牵张器维持4个月,右侧上颌骨自动向下生长,上下颌咬合关系恢复正常,取出下颌牵张成骨器,在牵张成骨新骨上植入MEDPOR假体并行颏成形术。手术完成后患者颜面不对称及畸形咬合关系均得到明显改善。     

颞下颌关节强直的牵引成骨治疗

目的探讨牵引成骨技术在颞下颌关节强直治疗中的应用。方法应用内置式牵引器治疗8例单侧颞下颌关节强直患者,患侧升支区制备一个1.5～2.0cm颊舌向等宽的骨间隙,并去除喙突,恢复开口度,升支后缘方块截骨,截骨块保留翼内肌附着,与下颌骨间安装牵引器,术后采用升支牵引成骨术,每日牵引1mm,分2次完成,重建颞下颌关节结构及恢复颞下颌关节功能,并坚持开口训练18个月以上。结果经牵引成骨后,患者牵引间隙成骨良好,新形成的关节形态得到改建,升支高度延长1.2～2.1cm,开口度达到正常。结论牵引成骨是治疗颞下颌关节强直的有效方法。     

下颌骨牵张成骨对颞下颌关节及咀嚼肌的影响

牵张成骨技术的日益成熟及其在临床应用的成功,使其在颅颌面骨尤其是下颌骨畸形中具有极大应用潜能。本综述了下颌骨牵张成骨对于颞下颌关节及咀嚼肌的影响,尤其是不同牵张方式对颞下颌关节的影响,同时阐述了影响牵张成骨对颞下颌关节及咀嚼肌作用的几个因素。     

牵张成骨延长一侧下颌骨对颞下颌关节的影响

目的：研究牵张成骨（DO）延长一侧下颌骨对双侧颞下颌关节（TMJ）的影响。方法：用DO技术将8只山羊的一侧下颌骨延长10mm，在牵张完成后第8和16周分别处死4只动物，取双侧关节作组织学和扫描电镜研究。结果：下颌一侧DO术后双侧髁状突发生适应性改建，髁突表面超微结构正常。结论：在适当的牵张条件下延长一侧下颌骨不会对TMJ造成病理性损害。     

Gap arthroplasty combined with distraction osteogenesis in the treatment of unilateral ankylosis of the temporomandibular joint and micrognathia

Our aim was to evaluate the efficacy of simultaneous gap arthroplasty and distraction osteogenesis (DO) in the treatment of unilateral ankylosis of the temporomandibular joint (TMJ) in patients with micrognathia. During the period January 2000-December 2006, 11 patients with unilateral ankylosis of the TMJ and micrognathia were treated with simultaneous gap arthroplasty, mandibular osteotomy, and implantation of a distractor. Mouth opening exercises were started on the first postoperative day and distraction on the fifth postoperative day. All patients had satisfactory mouth opening at follow-up, the mean (range) being 32.4 (28-37) mm in 13 to 58 months' follow-up. Mean length (range) of the mandibular body increased by DO was 12.4 (7-15) mm. Facial asymmetry was corrected and satisfactory occlusions achieved with the help of postoperative orthodontic treatment. We conclude that DO and gap arthroplasty can be used simultaneously in the treatment of patients with ankylosis of the TMJ and micrognathia.     

The sequential treatment of temporomandibular joint ankylosis with secondary deformities by distraction osteogenesis and arthroplasty or TMJ reconstruction

The purpose of this study was to evaluate the sequential treatment of patients with temporomandibular joint (TMJ) ankylosis and secondary deformities by distraction osteogenesis and subsequent arthroplasty or TMJ reconstruction. This study included 40 patients treated at a stomatological hospital in China; they ranged in age from 9 to 53 years (mean age 24.5 years). Ten of these patients were diagnosed with unilateral TMJ ankylosis and 30 with bilateral TMJ ankylosis. Twenty-seven patients also presented obstructive sleep apnoea–hypopnoea syndrome (OSAHS). All patients underwent distraction osteogenesis as the initial surgery, followed by arthroplasty or TMJ reconstruction. Some patients underwent orthognathic surgery to improve occlusion and face shape along with or after arthroplasty or TMJ reconstruction. The therapeutic effects were evaluated in terms of the improvements in maximum inter-incisal opening (MIO), appearance, and respiratory function. After the completion of treatment, all patients showed improvements in MIO and appearance, and the symptom of snoring disappeared. The airway space was significantly increased. Patient follow-up ranged from 6 to 85 months (mean 28.3 months), and four patients experienced relapse. This study suggests that treating TMJ ankylosis with secondary deformities by distraction osteogenesis as the initial surgery and arthroplasty or TMJ reconstruction as the second-stage treatment may achieve favourable outcomes, especially for patients with OSAHS; however, some patients may require orthognathic surgery.     

牵引成骨术治疗儿童单侧颞下颌关节强直伴OSAHS 4例报道

目的:评价牵引成骨术治疗儿童单侧颞下颌关节强直伴阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的治疗效果。方法:4例儿童单侧颞下颌关节强直伴发OSAHS患者,男女各2例,年龄5～13岁(中位年龄6.5岁)。均采用颞下颌关节成形术以恢复开口功能,下颌体牵引成骨术治疗OSAHS;其中3例行同期手术,1例行分期手术;单侧和双侧下颌体牵引各2例。固定期约3个月时行呼吸监护仪监测(PSG)复查和牵引器拆除术。结果:4例患儿OSAHS症状均消失,平均AHI由术前的42.7降到4.9,平均最低血氧饱和度由术前的74.3%上升到89.8%;平均开口度由6.5mm增加至25.5mm;面部畸形得到满意矫正。经过平均38.1个月(13～58个月)的随访,无1例复发。结论:下颌骨牵引成骨术联合颞下颌关节成形术能够有效地治疗儿童单侧颞下颌关节强直及其伴发的OSAHS、面部不对称畸形,并且可以同期手术。     

Simultaneous arthroplasty and distraction osteogenesis for the treatment of ankylosis of the temporomandibular joint and secondary mandibular deformities in children

The purpose of this study was to explore the use of simultaneous arthroplasty and distraction osteogenesis in the treatment of children with ankylosis of the temporomandibular joint (TMJ) and secondary mandibular deformities. Between January 2012 and December 2016, 17 children (7 boys and 10 girls, mean (range) age 7 (4–12) years) were treated. Preoperatively, the mean (range) maximal incisal opening was 1.4 (0–5) mm. Distraction osteogenesis was used to elongate the mandibular body or ramus, or both, after the release of ankylosis. Distraction began after five to seven days at a rate of 0.5 mm twice daily, and the distractor was removed three to five months after the completion of distraction. The mean (range) follow-up time after removal was 29.6 (16–45) months, and the distance of distraction was 14.4 (10–18) mm. After treatment, all patients had satisfactory outcomes, a good facial profile, alignment of the midline lower incisor, and a level occlusal plane. The mean (range) maximum incisal opening reached 35.7 (31–41) mm. Bone formation across the distraction gap was good. The mean minimum axial area of the airway increased from 61.4 mm to 96.4 mm (p < 0.01). No patients had a recurrence of ankylosis during follow up. Our results suggest that simultaneous arthroplasty and distraction osteogenesis is feasible in this group.     

Change in the posterior airway after mandibular distraction osteogenesis in patients with ankylosis of the temporomandibular joint: a retrospective study

Mandibular distraction osteogenesis (DO) has been shown to lead to considerable improvement in obstruction of the posterior airway space in patients with ankylosis of the temporomandibular joint (TMJ), and our objective was to find out if we could confirm these findings. Seventeen patients had spiral computed tomographic (CT) scans before and after DO. After treatment, the overall posterior airway space was enlarged in all three sections of the airway (oropharyngeal, glossopharyngeal, and laryngeal). We then compared rates of change in the airway among the sections using 2-dimensional and 3-dimensional assessments, and found that the rate of change in 3-dimensional assessment of volume was significantly higher than that in the 2-dimensional (62% compared with 34%). We also found that the higher 3-dimensional rate of change came from changes in the oropharyngeal and glossopharyngeal sections, while there was no significant difference between the 2- and 3-dimensional rates of change in the laryngeal section. Because the laryngeal section had the most robust enlargement after DO in both the overall area of the posterior airway space (increased by 54%) and volume (increased by 73%), we concluded that 3-dimensional assessments were more sensitive to smaller changes in the airway space during the operation. This suggests that 3-dimensional assessments are preferable in the prediction and evaluation of the effects of DO on the posterior airway space.