静脉剥脱联合硬化疗法治疗下肢静脉性溃疡

目的探讨大隐静脉高位结扎剥脱联合泡沫硬化剂注射对下肢静脉性溃疡的治疗效果。方法回顾性分析2013年7月~2015年8月收治的28例下肢静脉性溃疡患者临床资料,均行大隐静脉高位结扎剥脱联合泡沫硬化剂注射治疗。结果 28例患者成功接受大隐静脉高位结扎剥脱联合泡沫硬化剂注射术,平均手术时间为72(45~98)min,平均手术出血量为40(20~86)ml,平均每条肢体注射16(8~26)ml泡沫硬化剂,所有患者手术切口均一期愈合。术后活动性溃疡愈合27例(96.4%),平均愈合时间为15.8(10~28)d。1例溃疡面积较大者术后溃疡面积缩小后行植皮手术后愈合。3例患者术后小腿部曲张静脉附近呈现明显的炎症反应,予33%硫酸镁溶液湿敷后症状缓解,未出现下肢深静脉血栓形成等严重并发症。术后随访26例,平均11.6(3~26)个月,随访期间均未出现溃疡复发。结论大隐静脉高位结扎剥脱联合泡沫硬化剂注射治疗下肢静脉性溃疡安全、微创,临床效果满意。     

透光直视旋切术与腔镜深筋膜下结扎交通支静脉在静脉性溃疡治疗中的疗效比较研究

目的比较透光直视旋切术(TriVex)与腔镜深筋膜下结扎交通支静脉(SEPS)治疗静脉溃疡的效果。方法将我院在2009年1月至2011年6月间收治的静脉溃疡患者根据住院单双号分为TriVex组和SEPS组。TriVex组行大隐静脉高位结扎、抽剥和TriVex静脉旋切系统旋切术,对溃疡周围浅静脉予完全刨除;SEPS组行大隐静脉高位结扎、抽剥和腔镜深筋膜下结扎交通支静脉,对小腿曲张静脉及溃疡周围静脉行点状抽剥术。比较两组患者在溃疡愈合率、愈合时间及术后溃疡复发率的差异。结果两组患者的溃疡愈合率、愈合时间及溃疡复发率比较,差异无统计学意义(P>0.05),且均未发生深静脉血栓形成等严重并发症,但SEPS组术后皮下淤血或局部皮肤麻木感等轻微并发症高于TriVex组,而患者满意率低于TriVex组,两组差异有统计学意义(P<0.05)。结论 TriVex和SEPS均可有效治疗静脉溃疡,但SEPS可能会出现更多的皮下淤血或局部皮肤麻木感等轻微并发症,患者对TriVex的满意度更高。     

泡沫硬化剂注射联合TriVex系统治疗下肢静脉曲张的临床分析

目的探讨分析泡沫硬化剂注射联合TriVex系统治疗下肢静脉曲张的手术方法、技巧及疗效。方法纳入2014年10月至2016年4月在中山大学附属东华医院血管外科就诊的152例下肢静脉曲张患者,应用泡沫硬化剂注射联合TriVex系统进行治疗,评估治疗术后症状缓解,局部术区情况以及并发症发生率。结果对152例220条患肢采用大隐静脉主干高位结扎抽剥后泡沫硬化剂注射联合TriVex系统透光旋切术治疗静脉曲张患者,术后下肢明显的曲张畸形静脉消失,无一例患者出现复发,下肢酸胀、乏力等临床症状缓解,溃疡创面愈合。并发症主要是隐神经损伤、皮下硬结、血肿形成、软组织感染、深静脉血栓。结论大隐静脉高位结扎抽剥后泡沫硬化剂注射联合TriVex系统透光旋切术治疗下肢静脉曲张疗效显著,具有切口小、并发症少、复发率低等优点。     

超声监测下泡沫硬化剂治疗中度以上下肢静脉曲张疗效分析

目的 评价超声监测下泡沫硬化剂对中度以上下肢静脉曲张的治疗效果.方法 对32例临床分级C4～C6的患者实施大隐静脉高位结扎+腔镜下小腿交通静脉结扎+超声监视下大隐静脉主干及小腿曲张静脉泡沫硬化剂注射,通过随访评估症状的改善程度并用血管彩色多普勒超声对静脉闭塞情况进行观察.结果 32例患者共32条肢体(C4～C6)接受治疗.平均结扎小腿交通静脉3.2(1～5)条,每条肢体平均使用泡沫硬化剂27.5 ml.1例术后出现轻度胸闷但CT排除肺栓塞,4例曲张静脉附近呈现明显的炎性反应,3例局部存留迂曲静脉团块但超声多普勒检查未见血流信号,无脑缺血等严重并发症.术后平均随访4.8(1～10)个月,所有患肢术后静脉曲张消失,临床症状明显缓解.C5期9条患肢的溃疡均于术后3个月内愈合.结论 泡沫硬化剂注射可有效治疗中度以上下肢静脉曲张,联合腔镜下交通静脉结扎及大隐静脉高位结扎可以增加治疗的安全性.     

内镜筋膜下交通静脉结扎治疗慢性下肢静脉性溃疡的临床体会

目的:探讨内镜筋膜下交通静脉结扎术(subfascial endoscopic perforator surgery,SEPS)治疗慢性下肢静脉性溃疡的临床效果。方法:回顾分析78例,86条下肢慢性静脉性溃疡患者行内镜深筋膜下交通静脉离断+大隐静脉高位结扎并抽剥术的临床资料。结果:患者术后均恢复良好,浅静脉曲张消失,溃疡愈合,未发生明显并发症,随访1~3年,无皮肤溃疡及浅静脉曲张复发。结论:大隐静脉高位结扎剥脱术+SEPS治疗下肢静脉性溃疡有效,患者创伤小、康复快,效果好。     

聚桂醇注射联合大隐静脉抽剥缝扎治疗下肢静脉曲张

目的:探讨国产聚桂醇注射联合大隐静脉抽剥缝扎治疗下肢静脉曲张的临床效果.方法:选择我院从2010年4月至2011年8月应用大隐静脉主干抽剥联合聚桂醇泡沫硬化剂治疗下肢静脉曲张47条肢体,观察大隐静脉曲张的治疗效果.结果:47条肢体中42条肢体治疗2周后曲张静脉完全闭塞;5条肢体残留少许曲张静脉,再次注射后闭塞;6个月后复诊均无明显复发.结论:国产聚桂醇泡沫硬化剂注射联合大隐静脉抽剥缝扎治疗下肢静脉曲张的临床效果满意,是微创治疗下肢静脉曲张的新方法.     

单纯下肢浅静脉曲张手术治疗100例分析

笔者对经静脉造影确诊为单纯下肢浅静脉曲张100例(104条患肢)行小切口大隐静脉高位分段结扎抽剥，小腿部曲张浅静脉分段切除及交通静脉结扎术。治疗结果 ：切口均一期愈合，未发生手术后并发症。术后88例获随访，随访3个月至7年，除1例术后复发外，其余均疗效满意。提示小切口大隐静脉高位分段结扎、抽剥，小腿部曲张浅静脉分段切除（包括小隐静脉），加交通静脉结扎术具有切口小，手术时间短，疼痛轻，恢复快，效果良好等优点，有推广应用价值。     

下肢慢性静脉溃疡的综合治疗

目的探讨下肢慢性静脉溃疡的综合治疗方法。方法回顾性分析2012年7月~2013年1月我科收治的10例下肢慢性静脉溃疡患者（10条患肢）的临床资料,均采用大隐静脉高位结扎加抽剥并联合应用透光曲张静脉刨吸术、泡沫硬化剂注射、腔镜深筋膜下交通静脉结扎术等方法处理小腿病灶。分别在术前及术后3个月对临床症状的改善情况采集数据,按临床严重程度评分（VCSS）方法进行评估。结果患者均成功实施联合手术治疗方案,在术后的VCSS评分项目中得到改善[（12.3±2.06）v s （9.6±1.71）]。随访（6.70±1.45）个月,疼痛较前均有缓解,未发现患肢有曲张浅静脉残余或复发,8例溃疡基本愈合,仅有2例还有残余溃疡,但都控制在2 cm内,已愈合的溃疡未见复发。结论下肢慢性静脉溃疡经正确选择联合治疗方案进行处理后的效果是理想且安全的,而且其短期效果稳定。     

点式曲张静脉结扎术治疗下肢浅静脉曲张

下肢浅静脉曲张是外科领域的常见病,传统的治疗方法是大隐静脉高位结扎、剥脱器抽剥和交通支结扎。有人采用点式曲张静脉抽剥术已取得了良好疗效,我们将点式抽剥简化为点式结扎,也取得了满意效果,现报告如下:1资料与方法1.1一般资料:2003年6月~2005年6月我科用点式曲张静脉结扎术治疗单纯大隐静脉曲张病人56例(共70条肢体),其中男性32例,女性24例,年龄23~65岁,平均50岁。左侧28例,右侧14例,双侧14例。主要表现:下肢浅静脉曲张70条肢体,足靴区色素沉着48条肢体,湿疹样皮炎10条肢体,溃疡8条肢体。术前1d用龙胆紫准确标记曲张静脉走向及交通支…     

内镜下静脉交通支离断术治疗下肢静脉性溃疡

目的　探讨电视内镜下静脉交通支离断术的方法、优点及疗效。　方法　在电视内镜下行深筋膜下交通支离断术治疗明显浅静脉曲张、交通支及深静脉瓣膜功能不全伴有静脉性溃疡 ,其中 3例系术后复发性溃疡 ,行常规大隐静脉高位结扎、抽剥 ,小腿曲张浅静脉分段抽剥或结扎 ,同时行内镜下静脉交通支离断 ,对 1例内踝部巨大溃疡者术后 1周加做植皮。　结果　术后浅静脉曲张消失 ,静脉性溃疡 10天～ 30天内愈合 ,无切口感染并发症 ,1例巨大溃疡植皮成功 ,创面术后 18天愈合。　结论　内镜下静脉交通支离断术治疗下肢静脉性溃疡初步效果满意 ,术后并发症少。     

Superficial vein surgery and SEPS for chronic venous insufficiency

Venous insufficiency in its severe forms leads to skin changes which, in turn may be treated by surgical therapy. Interventions are directed towards correction of the underlying abnormal venous physiology. This involves removal of varicose veins and ablation of incompetent axial veins and relevant perforating veins. In performing ablation of saphenous vein reflux, techniques include high ligation with stripping, radiofrequency ablation, endovenous laser therapy, and foam sclerotherapy. Incompetent perforator interruption can be accomplished surgically by subfascial endoscopic perforator surgery (SEPS) or controlled sclerotherapy using ultrasound. A variety of techniques have emerged to manage the varicose veins themselves. Surgical treatment of chronic venous insufficiency with high ligation in the groin and inversion stripping of the great saphenous vein to the knee combined with stab avulsion of varicose veins continues to be the standard in treatment of varicose veins. There are few comparisons of sclerotherapy of perforating veins with SEPS, but SEPS has become the most popular of surgical options.     

Subfascial endoscopic perforator vein surgery: who benefits?

The advent of minimally invasive endoscopic surgery has rekindled interest in perforator vein ligation. Subfascial endoscopic perforator vein surgery (SEPS) utilizes techniques to interrupt incompetent perforators under direct vision using an endoscopic videocamera and instrumentation placed through small ports remote from the active ulcer or area of diseased skin. The safety and early efficacy of SEPS has been established in several studies, and it yields lower wound complication rates than observed with open surgical techniques such as the Linton procedure. Available results confirm the superiority of SEPS over open perforator ligation, but do not address the its role in the surgical treatment of advanced chronic venous insufficiency (CVI) and venous ulceration. Ablation of superficial reflux by high ligation and stripping of the greater saphenous vein with avulsion of branch varicosities is concomitantly performed in the majority of patients undergoing SEPS. The clinical and hemodynamic improvements attributable to SEPS thus are difficult to ascertain. As with open perforator ligation, clinical and hemodynamic results are better in patients with primary valvular incompetence (PVI) than in those with the postthrombotic (PT) syndrome. Until prospective, randomized, multicenter clinical trials are carried out to answer lingering questions regarding the efficacy of SEPS, the procedure is recommended in patients with advanced CVI secondary to PVI of superficial and perforating veins, with or without deep venous incompetence. The performance of SEPS in patients with PT syndrome remains controversial.     

腔镜深筋膜下交通静脉结扎治疗下肢静脉曲张

目的　观察腔镜深筋膜下交通静脉结扎 (SEPS)在下肢静脉曲张治疗中的疗效。　方法　 1 999年 1 1月～ 2 0 0 0年 1 2月手术治疗静脉曲张 1 0 8例 ,其中 34例 41侧患肢行 SEPS。男 1 6例 ,女 1 8例 ,年龄 2 0～ 79岁。病程 1～45年 ,平均 1 6.1年。双下肢病变 7例。 2 6例 30侧患肢有静脉性溃疡 ,溃疡直径 1 .5～ 1 2 .0 cm不等 ;8例 1 1侧患肢有色素沉着 ,皮肤病损 1个月～ 1 5年。根据病情分别或同时选用大隐静脉高位结扎和抽剥、小腿曲张浅静脉连续环形缝扎、股静脉瓣膜外修复成形和 SEPS术。　结果　 34例手术顺利 ;术后 1 9侧患肢溃疡 1个月内愈合 ,7侧患肢溃疡 3个月内愈合 ,4侧患肢行游离植皮后溃疡愈合。经术后 9～ 2 2个月的随访 ,溃疡无复发。　结论　 SEPS促进了静脉性溃疡的愈合 ,是治疗下肢静脉功能不全的重要方法之一。     

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目的 探讨腔镜深筋膜下结扎交通支静脉治疗下肢慢性静脉性溃疡的疗效。方法 手术治疗７例下肢静脉曲张病人,该７例均同时存在浅静脉倒流,交通支静脉功能不全,深静脉功能不全和静脉性溃疡。手术方式为腔镜深筋膜下交通支静脉结扎,大隐静脉高位结并抽剥和小腿曲张的浅静脉经连续环形缝扎术,其中５例同时行股浅静脉瓣膜外修复成形术。结果 术后肢体症状和浅静脉曲张消失,６例静脉性溃疡短期内愈合,１例明显缩小。结论 腔镜深     

Is the nihilistic approach to surgical reduction of superficial and perforator vein incompetence for venous ulcer justified?

OBJECTIVE: Twenty-five years ago, the senior author showed a 55% postoperative ulcer recurrence rate after open perforator ligation. Those data contributed to a nihilistic attitude toward incompetent perforating veins. Conversely, since the introduction of subfascial endoscopic perforator surgery (SEPS), we have undertaken ablation of superficial and perforator reflux as initial treatment in patients with ulcers (C6) or healed ulcers (C5). This report outlines our long-term results. METHODS: Between December 1994 and November 1999, SEPS was performed on 51 limbs in 45 patients with C5/C6 disease. Sixteen limbs underwent SEPS alone, and 35 had additional surgery on the greater saphenous vein (GSV), the lesser saphenous vein, or the tributary varicies. Data were collected according to the reporting standards in venous disease. Preoperative duplex scan of deep, superficial, and perforating veins was performed. Data were analyzed with Kaplan-Meier method, Mantel-Cox log-rank test, or t test. RESULTS: Of the 51 limbs that underwent SEPS, the GSV was stripped in 28. Twenty-nine were C6, and 22 were C5. Etiology was primary (Ep) in 25 limbs and secondary (Es) in 26 limbs. All limbs had duplex scan evidence of perforator incompetence (Ap), and deep insufficiency (A(D)) was seen in 39 cases (76%). Reflux predominated (P(R)). The clinical follow-up period was 0 to 82 months (median, 38 months). Venous disability scores improved from 9.8 before surgery to 4.2 at last follow-up (P <.05). Kaplan-Meier analysis showed 74% healing at 6 months. The presence of an ulcer more than 2 cm in diameter, secondary etiology, and SEPS without concomitant GSV stripping were associated (P <.05) with delayed healing. Among patients in whom ulcers healed or who were seen with healed ulcers, the 5-year ulcer recurrence rate was 13%. Lesser saphenous vein reflux was the only factor that correlated with increased ulcer recurrence. Deep system reflux as measured with duplex scan valve closure times did not correlate with the rate of ulcer healing or recurrence. CONCLUSION: Nihilism has no place in the management of venous disease in the 21st century. An aggressive approach to superficial and perforating vein reflux in this cohort of patients with C5 and C6 disease resulted in rapid ulcer healing and low 5-year recurrence rates. Prior saphenous vein stripping, large ulcers, and secondary etiology were associated with delayed healing. A less aggressive posture toward lesser saphenous vein reflux contributed to a higher recurrence rate in this subgroup of patients. These risk factors are useful in counseling patients as to their expected postoperative course; however, no combination of factors should a priori preclude surgical intervention in this group of patients.     

Early clinical outcomes after subfascial endoscopic perforator surgery (SEPS) and saphenous vein surgery in chronic venous insufficiency

BACKGROUND: Subfascial endoscopic perforator surgery (SEPS) has recently become popular as a minimally invasive way to treat chronic venous insufficiency (CVI) of the lower extremities. We report the early clinical outcomes of SEPS and saphenous vein surgery in a prospective series of Chinese patients who presented with severe CVI. METHODS: All patients referred to our hospital for the management of severe CVI (class IV disease or above) after January 1998 underwent SEPS using an ultrasonic scalpel in conjunction with saphenous vein surgery. All patients were followed up prospectively to assess ulcer healing, ulcer recurrence, and symptoms after SEPS. Clinical outcome was evaluated by the scoring system suggested by the Consensus Committee of the American Venous Forum on Chronic Venous Disease. RESULTS: Over a 24-month period, we performed 36 SEPS on 31 patients. Nineteen lower extremities (53%) had active or healing ulcers. Sapheno-femoral ligation was also performed in 33 limbs (92%). Four limbs (11%) developed superficial wound infection, and two (6%) had saphenous nerve dysesthesia. The mean clinical score and disability score decreased from 8.42 to 3.42 and 1.45 to 0.31 respectively, after a median follow-up of 14 months (range, 6-22) (p < 0.005). Eleven ulcers (58%) healed within 6 weeks after surgery. At 1-year follow-up, ulcer recurrence was found in two legs (11%). Conclusion: SEPS is safe and feasible. Early clinical results have shown a promising outcome in patients with severe chronic venous insufficiency.     

腔镜在下肢静脉性溃疡治疗中的应用

目的探讨腔镜在下肢慢性静脉功能不全(CVI)并发静脉性溃疡中的临床治疗经验与疗效。方法回顾性分析2004年5月至2011年4月期间我院应用腔镜治疗78例(88条患肢)下肢CVI并发静脉性溃疡患者的临床资料,患者均行大隐静脉高位结扎+腔内激光治疗(EVLT)+腔镜深筋膜下交通静脉离断术(SEPS)。结果所有患者手术顺利。SEPS手术时间15～30min,平均20min;术中出血量1～5ml,平均2ml;术后住院时间2～8d,平均5d。术后肢体酸胀感和曲张浅静脉消失,色素沉着区缩小。术后筋膜下血肿3例,皮下气肿2例,小腿胫前区及足靴区麻木感3例。所有患者4～6周溃疡愈合,随访0.5～5年,平均3.5年,仅1例复发,是由于足靴区交通静脉残留。结论 SEPS是治疗CVI并发静脉性溃疡的首选方法,具有创伤小、出血少、手术时间短、恢复快、并发症少、疗效显著等特点。     

Great Saphenous Vein Stripping with Liberal Use of Subfascial Endoscopic Perforator Vein Surgery (SEPS)

This study is based on a unique registry of 632 patients who underwent great saphenous vein (GSV) stripping and liberal use of subfascial endoscopic perforator vein surgery (SEPS) for minimal to severe lower limb venous insufficiency. Clinical examinations and color-coded duplex scanning were performed on a randomly selected, manageable sample of 170 limbs to assess the affect of early SEPS on junctional (saphenofemoral [SFJ] and/or saphenopopliteal [SPJ]) and perforator vein (PV) insufficiencies and superficial varicosities at a median of 6.5 years. PV incompetence was present in 68 legs (40%), as the sole transfascial insufficiency in 28 limbs and combined with SFJ or SPJ incompetence in 40 limbs. Junction incompetence alone characterized an additional 38 limbs, bringing the total transfascial insufficiency prevalence to 62%. Superficial varicosities affected 46% of limbs. Overall CEAP clinical class was unimproved beyond preoperative values. PV incompetence was associated with higher CEAP and clinical venous severity scores than were junctional insufficiencies alone. We concluded that PV incompetence alone or combined with junctional insufficiency is associated with increased symptoms and disease progression. The prevalence of SFJ, SPJ, and PV incompetence (62%) and recurrent varicosities (46%) suggests that early use of SEPS does not prevent disease progression and offers no benefit over GSV stripping in the absence of deep vein insufficiency or threatened ulceration.