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1.

Objectives:

To evaluate the shielding effect of thyroid collar for digital panoramic radiography.

Methods:

4 machines [Orthopantomograph® OP200 (Instrumentarium Dental, Tuusula, Finland), Orthophos CD (Sirona Dental Systems GmbH, Bensheim, Germany), Orthophos XG Plus (Sirona Dental Systems GmbH) and ProMax® (Planmeca Oy, Helsinki, Finland)] were used in this study. Average tissue-absorbed doses were measured using thermoluminescent dosemeter chips in an anthropomorphic phantom. Effective organ and total effective doses were derived according to the International Commission of Radiological Protection 2007 recommendations. The shielding effect of one collar in front and two collars both in front and at the back of the neck was measured.

Results:

The effective organ doses of the thyroid gland obtained from the 4 panoramic machines were 1.12 μSv for OP200, 2.71 μSv for Orthophos CD, 2.18 μSv for Orthophos XG plus and 2.20 μSv for ProMax, when no thyroid collar was used. When 1 collar was used in front of the neck, the effective organ doses of the thyroid gland were 1.01 μSv (9.8% reduction), 2.45 μSv (9.6% reduction), 1.76 μSv (19.3% reduction) and 1.70 μSv (22.7% reduction), respectively. Significant differences in dose reduction were found for Orthophos XG Plus and ProMax. When two collars were used, the effective organ doses of the thyroid gland were also significantly reduced for the two machines Orthophos XG Plus and ProMax. The same trend was observed in the total effective doses for the four machines.

Conclusions:

Wearing a thyroid collar was helpful when the direct digital panoramic imaging systems were in use, whereas for the indirect digital panoramic imaging systems, the thyroid collar did not have an extra protective effect on the thyroid gland and whole body.  相似文献   

2.

Objectives:

The purpose of the study is to evaluate the effectiveness of thyroid shielding in dental CBCT examinations using a paediatric anthropomorphic phantom.

Methods:

An ATOM® 706-C anthropomorphic phantom (Computerized Imaging Reference Systems Inc., Norfolk, VA) representing a 10-year-old child was loaded with six thermoluminescent dosemeters positioned at the level of the thyroid gland. Absorbed doses to the thyroid were measured for five commercially available thyroid shields using a large field of view (FOV).

Results:

A statistically significant thyroid gland dose reduction was found using thyroid shielding for paediatric CBCT examinations for a large FOV. In addition, a statistically significant difference in thyroid gland doses was found depending on the position of the thyroid gland. There was little difference in the effectiveness of thyroid shielding when using a lead vs a lead-equivalent thyroid shield. Similar dose reduction was found using 0.25- and 0.50-mm lead-equivalent thyroid shields.

Conclusions:

Thyroid shields are to be recommended when undertaking large FOV CBCT examinations on young patients.  相似文献   

3.

Objectives:

To test the dose-reducing capabilities of a novel thyroid protection device and a recently introduced cranial collimator to be used in orthodontic lateral cephalography.

Methods:

Cephalographic thyroid protector (CTP) was designed to shield the thyroid while leaving the cervical vertebrae depicted. Using a RANDO® head phantom (The Phantom Laboratory, Salem, NY) equipped with dosemeters and a Proline XC (Planmeca, Helsinki, Finland) cephalograph, lateral cephalograms were taken, and the effective dose (ED) was calculated for four protocols: (1) without shielding; (2) with CTP; (3) with CTP and anatomical cranial collimator (ACC); and (4) with a thyroid collar (TC).

Results:

The ED for the respective protocols was (1) 8.51; (2) 5.39; (3) 3.50; and (4) 4.97 µSv. The organ dose for the thyroid was reduced from 30.17 to 4.50 µSv in Protocols 2 and 3 and to 3.33 µSv in Protocol 4.

Conclusions:

The use of just the CTP (Protocol 2) resulted in a 36.8% reduction of the ED of a lateral cephalogram. This was comparable to the classical TC (Protocol 4). A 58.8% reduction of the ED was obtained when combining CTP and ACC (Protocol 3). The dose to the radiosensitive thyroid gland was reduced by 85% in Protocols 2 and 3 and by 89% in Protocol 4.  相似文献   

4.

Objective:

Evaluation of absolute radiation exposure values for interventional radiologists (IRs) using a multiaxis interventional flat-panel C-arm cone beam CT (CBCT) system with three-dimensional laser guidance for biopsy in a triple-modality, abdominal phantom.

Methods:

In the phantom, eight lesions were punctured in two different angles (in- and out-of-plane) using CBCT. One C-arm CT scan was performed to plan the intervention and one for post-procedural evaluation. Thermoluminescent dosemeters (TLDs) were used for dose measurement at the level of the eye lens, umbilicus and ankles on a pole representing the IRs. All measurements were performed without any lead protection. In addition, the dose–area product (DAP) and air kerma at the skin entrance point was documented.

Results:

Mean radiation values of all TLDs were 190 µSv for CBCT (eye lens: 180 µS, umbilicus: 230 µSv, ankle: 150 µSv) without a significant difference (p > 0.005) between in- and out-of-plane biopsies. In terms of radiation exposure of the phantom, the mean DAP was not statistically significantly different (p > 0.05) for in- and out-of-plane biopsies. Fluoroscopy showed a mean DAP of 7 or 6 μGym2, respectively. C-arm CT showed a mean DAP of 5150 or 5130 μGym2, respectively.

Conclusion:

In our setting, the radiation dose to the IR was distinctly high using CBCT. For dose reduction, it is advisable to pay attention to lead shielding, to increase the distance to the X-ray source and to leave the intervention suite for C-arm CT scans.

Advances in knowledge:

The results indicate that using modern navigation tools and CBCT can be accompanied with a relative high radiation dose for the IRs since detector angulation can make the use of proper lead shielding difficult.  相似文献   

5.

Objective:

A dedicated extremity cone beam CT (CBCT) was introduced recently, and is rapidly becoming an attractive modality for extremity imaging. This study aimed to evaluate the effectiveness of a curtain-shaped lead shielding in reducing the exposure of patients to scattered radiation in dedicated extremity CBCT.

Methods:

A dedicated extremity CBCT scanner was used. The lead shielding curtain was 42 × 60 cm with 0.5-mm lead equivalent. Scattered radiation dose from CBCT was measured using thermoluminescence dosimetry chips at 20 points, at different distances and directions from the CT gantry. Two sets of scattered radiation dose measurements were performed before and after installation of curtain-shaped lead shield, and the percentage reduction in dose in air was calculated.

Results:

Mean radiation exposure dose at measured points was 34.46 ± 48.40 μGy without curtains and 9.67 ± 4.53 μGy with curtains, exhibiting 71.94% reduction (p = 0.000). The use of lead shielding curtains significantly reduced scattered radiation at 0.5, 1.0 and 1.5 m from the CT gantry, with percent reductions of 84.8%, 58.0% and 35.5%, respectively (p = 0.000, 0.000 and 0.002). The percent reduction in the diagonal (+45°, −45°) and vertical forward (0°) directions were 86.3%, 83.1% and 77.7%, respectively, and were statistically significant (p = 0.029, 0.020 and 0.041).

Conclusion:

Shielding with lead curtains suggests an easy and effective method for reducing patient exposure to radiation in extremity CBCT imaging.

Advances in knowledge:

Lead shielding curtains are an effective technique to reduce scattered radiation dose in dedicated extremity CBCT, with higher dose reduction closer to the gantry opening.Plain radiographic examinations are routinely used in initial evaluation of bony injuries, but superimposition of structures and other inherent problems associated with this technique cause misdiagnosis.1 CT is widely used for more detailed evaluation of suspected injuries in extremities. Multidetector CT (MDCT) can provide medical practitioners with detailed morphological information on osseous and soft-tissue structures.More recently, cone beam CT (CBCT) has been introduced for extremity imaging.2 This application offers an attractive alternative with high spatial resolution, which enables detailed visualization of osseous structures, easy installation owing to its smaller size, and relatively low radiation dose compared with conventional MDCT scanners.37 There are an increasing number of papers reporting various clinical applications of CBCT, such as in CT angiography and in weight-bearing imaging.8,9 Like other imaging modalities using ionizing radiation, reducing patient radiation dose is an important issue.10 Patient radiation exposure can be largely categorized into the following two categories: (1) radiation dose within the field of view (FOV) and (2) scattered radiation extending beyond the FOV area. Although radiation dose within FOV has been a major concern regarding patient dose, we cannot neglect the out-of-field radiation that can affect radiosensitive organs such as the gonads and the thyroid gland in extremities imaging.Several approaches exist for reducing scattered radiation, including decreasing the overall radiation dose by adjusting the radiation source and shielding. Decreasing radiation exposure dose within FOV results in reduced out-of-FOV radiation because scattered radiation is positively correlated to the entrance surface dose.11 However, a certain amount of radiation dose is necessary within the FOV for maintaining image quality. Therefore, there are limitations on reducing the scattered radiation by adjusting the radiation source. Shielding materials can be placed between the radiation source and the areas where protection is needed for further reducing the out-of-field radiation. Various methods have been developed for reducing the scattered radiation, for example, lead apron, lead shield and radio-absorbable drape in the setting of fluoroscopy-guided procedures.12,13 However, there are no standardized methods for reducing the scattered radiation to patients in extremity scanning using mobile dedicated extremity CBCT.Therefore, we proposed a curtain-shaped radiation-absorbing material hung at the gantry outlet. The goal of this study was to evaluate the effectiveness of curtain-shaped lead shielding technique for reducing the radiation exposure in dedicated extremity CBCT.  相似文献   

6.

Objectives:

To determine the optimal kVp setting for a particular cone beam CT (CBCT) device by maximizing technical image quality at a fixed radiation dose.

Methods:

The 3D Accuitomo 170 (J. Morita Mfg. Corp., Kyoto, Japan) CBCT was used. The radiation dose as a function of kVp was measured in a cylindrical polymethyl methacrylate (PMMA) phantom using a small-volume ion chamber. Contrast-to-noise ratio (CNR) was measured using a PMMA phantom containing four materials (air, aluminium, polytetrafluoroethylene and low-density polyethylene), which was scanned using 180 combinations of kVp/mA, ranging from 60/1 to 90/8. The CNR was measured for each material using PMMA as background material. The pure effect of kVp and mAs on the CNR values was analysed. Using a polynomial fit for CNR as a function of mA for each kVp value, the optimal kVp was determined at five dose levels.

Results:

Absorbed doses ranged between 0.034 mGy mAs−1 (14 × 10 cm, 60 kVp) and 0.108 mGy mAs−1 (14 × 10 cm, 90 kVp). The relation between kVp and dose was quasilinear (R2 > 0.99). The effect of mA and kVp on CNR could be modelled using a second-degree polynomial. At a fixed dose, there was a tendency for higher CNR values at increasing kVp values, especially at low dose levels. A dose reduction through mA was more efficient than an equivalent reduction through kVp in terms of image quality deterioration.

Conclusions:

For the investigated CBCT model, the most optimal contrast at a fixed dose was found at the highest available kVp setting. There is great potential for dose reduction through mA with a minimal loss in image quality.  相似文献   

7.

Objective:

In 2011, the International Commission on Radiological Protection (ICRP) recommended a substantial reduction in the equivalent dose limit for the lens of the eye, in line with a reduced threshold of absorbed dose for radiation-induced cataracts. This is of particular relevance in interventional radiology (IR) where it is well established that staff doses can be significant, however, there is a lack of data on IR eye doses in terms of Hp(3). Hp(3) is the personal dose equivalent at a depth of 3 mm in soft tissue and is used for measuring lens dose. We aimed to obtain a reliable estimate of eye dose to IR operators.

Methods:

Lens doses were measured for four interventional radiologists over a 3-month period using dosemeters specifically designed to measure Hp(3).

Results:

Based on their typical workloads, two of the four interventional radiologists would exceed the new ICRP dose limit with annual estimated doses of 31 and 45 mSv to their left eye. These results are for an “unprotected” eye, and for IR staff who routinely wear lead glasses, the dose beneath the glasses is likely to be significantly lower. Staff eye dose normalized to patient kerma–area product and eye dose per procedure have been included in the analysis.

Conclusion:

Eye doses to IR operators have been established using a dedicated Hp(3) dosemeter. Estimated annual doses have the potential to exceed the new ICRP limit.

Advances in knowledge:

We have estimated lens dose to interventional radiologists in terms of Hp(3) for the first time in an Irish hospital setting.Interventional radiology (IR) procedures can result in occupational radiation doses that are high enough to warrant concern.16 While there is good awareness and understanding of radiation risks to staff from IR procedures, a lack of reliable values for eye doses has persisted. Recent publications have attempted to address this and have established that dose to the eyes can be significant, particularly if the X-ray tube is positioned over the patient table and if no ceiling-mounted lead screen or lead glasses are used;716 however, more data on lens dose, particularly in terms of Hp(3) (personal dose equivalent at 3 mm in soft tissue), is required.15,16

Revised International Commission on Radiological Protection dose limit

In April 2011, the International Commission on Radiological Protection (ICRP) published a statement on tissue reactions recommending an equivalent dose limit for the lens of the eye of 20 mSv per annum.17 This is a considerable reduction from the previous equivalent dose limit of 150 mSv per annum.18 Since this statement was released, awareness in the scientific literature has grown at a rapid pace and the need for improved eye lens dosimetry has been acknowledged.19,20 Although the rationale for reduction in the eye lens limit has been debated in the literature,1923 the limit is now on a firm footing within Europe as it has been adopted into the new European Union (EU) basic safety standards directive.24 The directive must be transposed into national legislation by EU member states within a period of 4 years. Efforts to establish reliable estimates of eye doses prior to legislative changes will assist with the transition to this significantly lower limit. The goal of this study was to obtain a reliable estimate of occupational eye doses to IR operators in terms of Hp(3).  相似文献   

8.

Objectives:

When bitewing radiographs are not possible (e.g. patients with special needs), oblique lateral radiographs may offer an alternative. The aims of this study were to assess the impact of horizontal projection angulation, focus-to-skin distance, exposure time and age of the patient on the equivalent radiation dose of several organs in the head and neck region by means of personal computer X-ray Monte Carlo (PCXMC) calculations and to assess the dose obtained from conventional bitewing radiographs.

Methods:

PCXMC v. 2.0 software (STUK®, Helsinki, Finland) was used to estimate the equivalent radiation doses and the total effective dose. Three exposure times, five age categories, two focus-to-skin distances and eight horizontal geometric angulations were assumed. The organs involved were the thyroid gland, oesophagus, salivary glands, bone marrow, oral mucosa, skull, cervical spine and skin. A similar calculation was also performed for bitewings taken with a rectangular collimator.

Results and conclusion

Bitewings taken with rectangular collimation decrease the radiation burden of the patient to 50%, compared with circular collimation. In the oblique lateral radiographs, focus-to-skin distance, patient''s age and beam collimation had a significant impact on the equivalent doses measured in this study. Exposure time had a significant impact on the equivalent doses of the salivary glands, oral mucosa, skull and skin. Horizontal angulations had a significant impact on the equivalent doses of the thyroid gland, bone marrow, oral mucosa, skull and cervical spine. The total effective radiation dose was significantly influenced by all parameters investigated in this study.  相似文献   

9.

Purpose

This study was designed to evaluate the reduction of the eye lens dose when wearing protective eyewear in interventional radiology and to identify conditions that optimize the efficacy of radiation safety glasses.

Methods

The dose reduction provided by different models of radiation safety glasses was measured on an anthropomorphic phantom head. The influence of the orientation of the phantom head on the dose reduction was studied in detail. The dose reduction in interventional radiological practice was assessed by dose measurements on radiologists wearing either leaded or no glasses or using a ceiling suspended screen.

Results

The different models of radiation safety glasses provided a dose reduction in the range of a factor of 7.9–10.0 for frontal exposure of the phantom. The dose reduction was strongly reduced when the head is turned to the side relative to the irradiated volume. The eye closest to the tube was better protected due to side shielding and eyewear curvature. In clinical practice, the mean dose reduction was a factor of 2.1. Using a ceiling suspended lead glass shield resulted in a mean dose reduction of a factor of 5.7.

Conclusions

The efficacy of radiation protection glasses depends on the orientation of the operator’s head relative to the irradiated volume. Glasses can offer good protection to the eye under clinically relevant conditions. However, the performance in clinical practice in our study was lower than expected. This is likely related to nonoptimized room geometry and training of the staff as well as measurement methodology.  相似文献   

10.

Objectives:

The aim of this study was to calculate organ and effective doses for a range of available protocols in a particular cone beam CT (CBCT) scanner dedicated to dentistry and to derive effective dose conversion factors.

Methods:

Monte Carlo simulations were used to calculate organ and effective doses using the International Commission on Radiological Protection voxel adult male and female reference phantoms (AM and AF) in an i-CAT CBCT. Nine different fields of view (FOVs) were simulated considering full- and half-rotation modes, and also a high-resolution acquisition for a particular protocol. Dose–area product (DAP) was measured.

Results:

Dose to organs varied for the different FOVs, usually being higher in the AF phantom. For 360°, effective doses were in the range of 25–66 μSv, and 46 μSv for full head. Higher contributions to the effective dose corresponded to the remainder (31%; 27–36 range), salivary glands (23%; 20–29%), thyroid (13%; 8–17%), red bone marrow (10%; 9–11%) and oesophagus (7%; 4–10%). The high-resolution protocol doubled the standard resolution doses. DAP values were between 181 mGy cm2 and 556 mGy cm2 for 360°. For 180° protocols, dose to organs, effective dose and DAP were approximately 40% lower. A conversion factor (DAP to effective dose) of 0.130 ± 0.006 μSv mGy−1 cm−2 was derived for all the protocols, excluding full head. A wide variation in dose to eye lens and thyroid was found when shifting the FOV in the AF phantom.

Conclusions:

Organ and effective doses varied according to field size, acquisition angle and positioning of the beam relative to radiosensitive organs. Good positive correlation between calculated effective dose and measured DAP was found.  相似文献   

11.

Objectives:

To determine the effective dose and CT dose index (CTDI) for a range of imaging protocols using the Sirona GALILEOS® Comfort CBCT scanner (Sirona Dental Systems GmbH, Bensheim, Germany).

Methods:

Calibrated optically stimulated luminescence dosemeters were placed at 26 sites in the head and neck of a modified RANDO® phantom (The Phantom Laboratory, Greenwich, NY). Effective dose was calculated for 12 different scanning protocols. CTDI measurements were also performed to determine the dose–length product (DLP) and the ratio of effective dose to DLP for each scanning protocol.

Results:

The effective dose for a full maxillomandibular scan at 42 mAs was 102 ± 1 μSv and remained unchanged with varying contrast and resolution settings. This compares with 71 μSv for a maxillary scan and 76 μSv for a mandibular scan with identical milliampere-seconds (mAs) at high contrast and resolution settings.

Conclusions:

Changes to mAs and beam collimation have a significant influence on effective dose. Effective dose and DLP vary linearly with mAs. A collimated maxillary or mandibular scan decreases effective dose by approximately 29% and 24%, respectively, as compared with a full maxillomandibular scan. Changes to contrast and resolution settings have little influence on effective dose. This study provides data for setting individualized patient exposure protocols to minimize patient dose from ionizing radiation used for diagnostic or treatment planning tasks in dentistry.  相似文献   

12.

Objectives:

The aim of this work was to estimate the doses to radiosensitive organs in the head of a young child undergoing panoramic radiography and to establish the effectiveness of a short collimator in reducing dose.

Methods:

Thermoluminescent dosemeters were used in a paediatric head phantom to simulate an examination on a 5-year-old child. The panoramic system used was an Instrumentarium OP200 D (Instrumentarium Dental, Tuusula, Finland). The collimator height options were 110 and 140 mm. Organ doses were measured using exposure programmes intended for use with adult and child size heads. The performance of the automatic exposure control (AEC) system was also assessed.

Results:

The short collimator reduced the dose to the brain and the eyes by 57% and 41%, respectively. The dose to the submandibular and sublingual glands increased by 32% and 20%, respectively, when using a programme with a narrower focal trough intended for a small jaw. The effective dose measured with the short collimator and paediatric programme was 7.7 μSv. The dose to the lens of the eye was 17 μGy. When used, the AEC system produced some asymmetry in the dose distribution across the head.

Conclusions:

Panoramic systems when used to frequently image children should have programmes specifically designed for imaging small heads. There should be a shorter collimator available and programmes that deliver a reduced exposure time and allow reduction of tube current. Programme selection should also provide flexibility for focal trough size, shape and position to match the smaller head size.  相似文献   

13.

Objectives:

This study investigated the absorbed doses in a full anthropomorphic body phantom from two different panoramic radiography devices, performing protocols with and without applying a lead apron.

Methods:

A RANDO® full body phantom (Alderson Research Laboratories Inc., Stamford, CT) was equipped with 110 thermoluminescent dosemeters at 55 different sites and set up in two different panoramic radiography devices [SCANORA® three-dimensional (3D) (SOREDEX, Tuusula, Finland) and ProMax® 3D (Planmeca, Helsinki, Finland)] and exposed. Two different protocols were performed in the two devices. The first protocol was performed without any lead shielding, whereas the phantom was equipped with a standard adult lead apron for the second protocol.

Results:

A two-tailed paired samples t-test for the SCANORA 3D revealed that there is no difference between the protocol using lead apron shielding (m = 87.99, s = 102.98) and the protocol without shielding (m = 87.34, s = 107.49), t(54) = −0.313, p > 0.05. The same test for the ProMax 3D showed that there is also no difference between the protocol using shielding (m = 106.48, s = 117.38) and the protocol without shielding (m = 107.75, s = 114,36), t(54) = 0.938, p > 0.05.

Conclusions:

In conclusion, the results of this study showed no statistically significant differences between a panoramic radiography with or without the use of lead apron shielding.  相似文献   

14.
15.

Purpose

We aimed to develop and validate a simplified, novel quantification method for radioiodine whole-body scans (WBSs) as a predictor for the treatment response in differentiated thyroid carcinoma (DTC) patients with distant metastasis.

Methods

We retrospectively reviewed serial WBSs after radioiodine treatment from 2008 to 2011 in patients with metastatic DTC. For standardization of TSH simulation, only a subset of patients whose TSH level was fully enhanced (TSH > 80 mU/l) was enrolled. The radioiodine scan index (RSI) was calculated by the ratio of tumor-to-brain uptake. We compared correlations between the RSI and TSH-stimulated serum thyroglobulin (TSH_s_Tg) level and between the RSI and Tg reduction rate of consecutive radioiodine treatments.

Results

A total of 30 rounds of radioiodine treatment for 15 patients were eligible. Tumor histology was 11 papillary and 4 follicular subtypes. The TSH_s_Tg level was mean 980 ng/ml (range, 0.5–11,244). The Tg reduction rate after treatment was a mean of −7 % (range, −90 %–210 %). Mean RSI was 3.02 (range, 0.40–10.97). RSI was positively correlated with the TSH_s_Tg level (R2 = 0.3084, p = 0.001) and negatively correlated with the Tg reduction rate (R2 = 0.2993, p = 0.037). The regression equation to predict treatment response was as follows: Tg reduction rate = −14.581 × RSI + 51.183.

Conclusions

Use of the radioiodine scan index derived from conventional WBS is feasible to reflect the serum Tg level in patients with metastatic DTC, and it may be useful for predicting the biologic treatment response after radioiodine treatment.  相似文献   

16.

Objective:

To assess the influence and significance of the use of iterative reconstruction (IR) algorithms on patient dose in CT in Australia.

Methods:

We examined survey data submitted to the Australian Radiation Protection and Nuclear Safety Agency (ARPANSA) National Diagnostic Reference Level Service (NDRLS) during 2013 and 2014. We compared median survey dose metrics with categorization by scan region and use of IR.

Results:

The use of IR results in a reduction in volume CT dose index of between 17% and 44% and a reduction in dose–length product of between 14% and 34% depending on the specific scan region. The reduction was highly significant (p < 0.001, Wilcoxon rank-sum test) for all six scan regions included in the NDRLS. Overall, 69% (806/1167) of surveys included in the analysis used IR.

Conclusion:

The use of IR in CT is achieving dose savings of 20–30% in routine practice in Australia. IR appears to be widely used by participants in the ARPANSA NDRLS with approximately 70% of surveys submitted employing this technique.

Advances in knowledge:

This study examines the impact of the use of IR on patient dose in CT on a national scale.  相似文献   

17.

Objective:

To evaluate the dosimetric effects of roll-rotational setup errors of stereotactic ablative radiotherapy (SABR) for lung cancer using volumetric modulated arc therapy (VMAT).

Methods:

A total of 23 lung SABR cases were evaluated retrospectively. Each of the planning CT images was intentionally rotated by ±1°, ±2° and ±3°. After that, to simulate the translational couch correction, rotated CT images were moved along the x, y and z axis to match the centroid of the target volume in the rotated CT images with that in the original CT images. The differences in D95% and V100% of the target volume, D0.35cc of spinal cord, D0.35cc and D5cc of oesophagus and V20Gy of lung between the original and the rotated CT images were calculated.

Results:

The average differences in D95% and V100% of target volume, D0.35cc of spinal cord, D0.35cc and D5cc of oesophagus and V20Gy of lung were −0.3% ± 0.4% and −0.7% ± 2.4%, 1.6 ± 27.9 cGy, −1.6 ± 37.6 cGy, 15.9 ± 25.3 cGy and 0.0% ± 0.1%, respectively. The dosimetric changes in organs at risk (OARs) near the target volume were sometimes considerable due to roll-rotational setup errors, despite the translational correction, and those were patient specific.

Conclusion:

In the case of coplanar VMAT for lung SABR, dosimetric changes to the target volume due to roll-rotational setup errors could be compensated by translational correction, whereas those to the OARs could not in some cases.

Advances in knowledge:

Roll-rotational setup errors would increase the dose to OARs despite the translational correction.  相似文献   

18.

Purpose

Salivary gland scintigraphy (SGS) provides an objective means of diagnosing salivary gland dysfunction in Sjögren’s syndrome (SS) patients and in thyroid cancer patients after radioactive iodine (RAI) therapy. In the present study, SGS was performed in SS patients and in thyroid cancer patients post-RAI, and scintigraphic parameters were compared.

Methods

Twenty-eight SS patients (males:females = 1:27, age 53.3 ± 11.9 years), 28 controls (males:females = 3:25, age 54.1 ± 10.1 years), and 92 thyroid cancer patients (males:females = 28:64, age 46.2 ± 12.9) who had undergone a session of high-dose RAI therapy (mean dose, 5.2 ± 1.5 GBq) were included. SGS was performed using Tc-99m pertechnetate (925 MBq). Scintigraphic parameters (parotid uptake ratio PU, submandibular uptake ratio SU, percentage parotid excretion %PE, and percentage submandibular excretion %SE) were measured and compared for SS, thyroid cancer post-RAI, and control patients.

Results

PU, SU, %SE, and %PE were all significantly lower in SS than in post-RAI thyroid cancer or control patients (p < 0.05), whereas only %PE was significantly lower in post-RAI thyroid cancer patients than in controls (p < 0.05). SU and %SE were found to be correlated with the unstimulated whole salivary flow rate.

Conclusion

Scintigraphic parameters derived from SGS can play a crucial role in the detection of salivary gland dysfunction in SS patients and in post-RAI thyroid cancer patients.  相似文献   

19.

Objective:

The aim of this study was to develop a low-dose protocol suitable for cone beam CT (CBCT) examination of an impacted maxillary canine in children by using a combination of dosimetry with subjective and objective image quality assessment.

Methods:

Radiation dose and image quality measurements were made using a dental CBCT machine. An image quality phantom was used to investigate the relationship between objective image quality and dose–area product (DAP) for a broad range of exposure settings. Subjective image quality assessment was achieved using a paediatric skull phantom submerged in a water bath for the same range of exposure settings. Eight clinicians assessed each CBCT data set for nine aspects of image quality using a five-point rating scale of agreement.

Results:

Acceptable image quality, defined using subjective judgements by the clinicians of the skull phantom images, was achievable with DAP values of 127 mGy cm2 or greater and a polytetrafluoroethylene (PTFE) contrast-to-noise ratio (CNR) of 4.8 or greater. A cautious choice was made to recommend a low-dose protocol of 80 kV and 3 mA for implementation into clinical practice, corresponding to a DAP value of 146 mGy cm2 and a PTFE CNR of 5.0.

Conclusion:

A low-dose protocol for this particular CBCT machine was established which represents as much as a 50% reduction compared with manufacturer''s recommendations.

Advances in knowledge:

To the authors'' best knowledge, this is the first study that addresses dose optimization in paediatric clinical protocols in dental CBCT. Furthermore, this study explores the relationship between radiation dose, objective and subjective image quality.  相似文献   

20.

Objective:

To identify a useful predictor of thyroid-associated ophthalmopathy (TAO) from orbital CT images; to evaluate the orbital fat and extraocular muscle area ratio as a CT-derived measure; and to investigate the correlations between this ratio and the clinical manifestations in mild-to-moderate TAO.

Methods:

Between January 2012 and March 2013, 44 patients with TAO and 23 controls were studied prospectively. All of the patients underwent ophthalmic examinations, including clinical activity score, exophthalmometry, clinical photographs, alternate prism and cover test, duction and version test, Hess screen test, binocular single vision test, thyroid function tests and orbital CT. The cross-sectional areas of the four rectus muscles, superior oblique muscle, optic nerve and total orbit area were calculated in the coronal view 6 mm posterior from the posterior pole of globe.

Results:

The cross-sectional area measured on orbital CT showed increased orbital fat in patients with TAO and an increased orbital fat to total orbit area ratio (fat/orbit) in TAO with retraction and proptosis. There were significant correlations between fat/orbit and margin reflex distance 1 (p = 0.022), margin reflex distance 2 (p = 0.013) and the exophthalmometric value (p = 0.007).

Conclusion:

The orbital fat to total orbit area ratio (fat/orbit) is a useful diagnostic index in mild-to-moderate TAO.

Advances in knowledge:

The orbital CT offers a useful diagnostic index in TAO.  相似文献   

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