A dysfunctional miR-1-TRPS1-MYOG axis drives ERMS by suppressing terminal myogenic differentiation

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CD39 Produced from Human GMSCs Regulates the Balance of Osteoclasts and Osteoblasts through the Wnt/β-Catenin Pathway in Osteoporosis

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An iPSC-derived exosome-pulsed dendritic cell vaccine boosts antitumor immunity in melanoma

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Sonic Hedgehog Effectively Improves Oct4-Mediated Reprogramming of Astrocytes into Neural Stem Cells

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An Endogenous Anti-aging Factor,Sonic Hedgehog,Suppresses Endometrial Stem Cell Aging through SERPINB2

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CRISPR-mediated MECOM depletion retards tumor growth by reducing cancer stem cell properties in lung squamous cell carcinoma

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Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCs

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HucMSC-Derived Exosomes Mitigate the Age-Related Retardation of Fertility in Female Mice

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Understanding and overcoming adverse consequences of genome editing on hematopoietic stem and progenitor cells

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Enhanced adipose-derived stem cells with IGF-1-modified mRNA promote wound healing following corneal injury

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Aptamers: Cutting edge of cancer therapies

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Tryptophanyl-tRNA Synthetase,a Novel Damage-Induced Cytokine,Significantly Increases the Therapeutic Effects of Endometrial Stem Cells

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TGFB1/INHBA Homodimer/Nodal-SMAD2/3 Signaling Network: A Pivotal Molecular Target in PDAC Treatment

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Catalase,a therapeutic target in the reversal of estrogen-mediated aging

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Broadening prime editing toolkits using RNA-Pol-II-driven engineered pegRNA

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Efficient polymer nanoparticle-mediated delivery of gene editing reagents into human hematopoietic stem and progenitor cells

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Lipid nanoparticle-mediated silencing of osteogenic suppressor GNAS leads to osteogenic differentiation of mesenchymal stem cells in vivo

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Bone marrow mesenchymal stem cell-derived exosomal miR-34c-5p ameliorates RIF by inhibiting the core fucosylation of multiple proteins

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Lysophosphatidic Acid Receptor 4 Is Transiently Expressed during Cardiac Differentiation and Critical for Repair of the Damaged Heart

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Lentiviral vector ALS20 yields high hemoglobin levels with low genomic integrations for treatment of beta-globinopathies

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