Decoding the regulatory roles of non-coding RNAs in cellular metabolism and disease

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The emerging regulatory roles of long non-coding RNAs implicated in cancer metabolism

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Terbinafine prevents colorectal cancer growth by inducing dNTP starvation and reducing immune suppression

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Bulk and single-cell transcriptome profiling reveal the metabolic heterogeneity in human breast cancers

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An SCD1-dependent mechanoresponsive pathway promotes HCC invasion and metastasis through lipid metabolic reprogramming

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Dysregulated m6A modification promotes lipogenesis and development of non-alcoholic fatty liver disease and hepatocellular carcinoma

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Combined thioredoxin reductase and glutaminase inhibition exerts synergistic anti-tumor activity in MYC-high high-grade serous ovarian carcinoma

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FOXP3 expression diversifies the metabolic capacity and enhances the efficacy of CD8 T cells in adoptive immunotherapy of melanoma

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Endocrine modulation of brain-skeleton axis driven by neural stem cell-derived perilipin 5 in the lipid metabolism homeostasis for bone regeneration

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A Pharmacological Chaperone Therapy for Acute Intermittent Porphyria

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Epigenetic strategies to boost CAR T cell therapy

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A Mitochondrial VDAC1-Based Peptide Greatly Suppresses Steatosis and NASH-Associated Pathologies in a Mouse Model

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Broad-acting therapeutic effects of miR-29b-chitosan on hypertension and diabetic complications

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An antisense circular RNA circSCRIB enhances cancer progression by suppressing parental gene splicing and translation

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Self-Replicating RNAs Drive Protective Anti-tumor T Cell Responses to Neoantigen Vaccine Targets in a Combinatorial Approach

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Comparison of dystrophin expression following gene editing and gene replacement in an aged preclinical DMD animal model

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Prognostic Value of Left Atrial Strain in Aortic Stenosis: A Competing Risk Analysis

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Computational Analysis Concerning the Impact of DNA Accessibility on CRISPR-Cas9 Cleavage Efficiency

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CRISPR-Cas-mediated transcriptional modulation: The therapeutic promises of CRISPRa and CRISPRi

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Evidence in primates supporting the use of chemogenetics for the treatment of human refractory neuropsychiatric disorders

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