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Rosa机器人辅助立体定向颅内活检术的临床应用
引用本文:邬,立,孙允伟,陆,斌,周子健,李方宝,李,洛.Rosa机器人辅助立体定向颅内活检术的临床应用[J].中国临床神经外科杂志,2021,26(8):584-586.
作者姓名:    孙允伟      周子健  李方宝    
摘    要:目的 探讨Rosa机器人辅助下立体定向颅内活检术的临床应用效果。方法 回顾性分析2018年10月至2020年8月在Rosa机器人辅助下进行颅内占位立体定向活检术的33例病人的临床资料。结果 术中没有发生导航故障,所有程序都如期完成。33例进行76个靶点穿刺活检术,术后未发现颅内出血,术后无癫痫发作。33例活检阳性率为100%,其中胶质瘤21例,弥漫大B细胞淋巴瘤5例,血管畸形2例,转移性腺瘤1例,生殖细胞肿瘤2例,间变性脑膜瘤1例,炎性脱髓鞘1例。21例胶质瘤中,检测出IDH-1突变6例(28.6%),MGMT启动子甲基化16例(76.2%)。1例间变性少突胶质细胞瘤检测出1p/19q杂合性缺失。结论 Rosa机器人辅助立体定向无框架活检术是一种相对安全,可行的操作,可用于颅内病变的组织学和分子诊断。

关 键 词:颅内病变  Rosa机器人  立体定向活检术

Clinical application of Rosa robot-assisted stereotactic intracranial biopsy
WU Li,SUN Yun-wei,LU Bin,ZHOU Zi-jian,LI Fang-bao,LI Luo..Clinical application of Rosa robot-assisted stereotactic intracranial biopsy[J].Chinese Journal of Clinical Neurosurgery,2021,26(8):584-586.
Authors:WU Li  SUN Yun-wei  LU Bin  ZHOU Zi-jian  LI Fang-bao  LI Luo
Affiliation:Department of Neurosurgery, Eastern Branch, Qingdao Municipal Hospital, Qingdao 266000, China
Abstract:Objective To explore the efficacy of Rosa robot-assisted stereotactic intracranial biopsy. Methods The clinical data of 33 patients with intracranial lesion who underwent Rosa robot-assisted stereotactic intracranial biopsy from October 2018 from August 2020. Results There was no navigation failure during the operation, and all procedures were completed successfully. Seven-six biopses were performed on these 33 patients, with no intracranial hemorrhage and epileptic seizures after the operation. The positive rate was 100%, including 21 patients with glioma, 5 with diffuse large B-cell lymphoma, 2 with vascular malformation, 1 with metastatic adenoma, 2 with germ cell tumor, 1 with anaplastic meningioma, and 1 with inflammatory demyelination. Of 21 patients with glioma, IDH-1 mutation was detected in 6 patients (28.6%), and MGMT promoter methylation was detected in 16 patients (76.2%). The loss of 1p/19q heterozygosity was found in 1 patient with anaplastic oligodendroglioma. Conclusions Rosa robot-assisted stereotactic frameless biopsy is a relatively safe and feasible operation, which can be used for histological and molecular diagnosis of intracranial lesions.
Keywords:Intracranial lsion  Rosa robot  Stereotactic biopsy
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