| 1例重度急性胰腺炎患者抗感染治疗的药学监护 |
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| 引用本文： | 张在丽,陈婷,崔敏,李莉霞.1例重度急性胰腺炎患者抗感染治疗的药学监护[J].药物流行病学杂志,2018(9):621-625. |
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| 作者姓名： | 张在丽 陈婷 崔敏 李莉霞 |
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| 作者单位： | 1.上海交通大学医学院附属仁济医院药学部 上海 200127；2.上海交通大学医学院附属新华医院药学部 |
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| 基金项目： | 上海市临床药学重点专科建设项目（编号：2016 40044 002）；上海市卫生计生系统重要薄弱学科建设项目（编号：2016ZB0304） |
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| 摘 要： | 摘 要临床药师参与1例重度急性胰腺炎患者的药物治疗，结合患者病史、临床症状及实验室指标等，根据病原学检测结果，借助万古霉素血药浓度监测进行抗感染方案调整，并协助医生对患者制定个体化用药方案。经治疗后，患者病情得到基本控制，且未出现相关药品不良反应。提示临床药师在参与患者治疗过程中，可结合患者特殊的生理病理状态、药物浓度监测及临床反应等，协助临床医师优化药物治疗方案，提高患者用药的有效性和安全性。
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| 关 键 词： | 重度急性胰腺炎 万古霉素 血药浓度 肥胖 肾功能亢进 药学监护 |
Pharmaceutical Care for One Case of Severe Acute Pancreatitis in Anti Infective Therapy |
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| Zhang Zaili,Chen Ting,Cui Min,Li Lixia.Pharmaceutical Care for One Case of Severe Acute Pancreatitis in Anti Infective Therapy[J].Chinese Journal of Pharmacoepidemiology,2018(9):621-625. |
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| Authors: | Zhang Zaili Chen Ting Cui Min Li Lixia |
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| Abstract: | ABSTRACTClinical pharmacists by participating in a case of severe acute pancreatitis patients with drug therapy, combined with the medical history, clinical symptoms and laboratory results, the testing results of etiology and blood drug concentration of vancomycin for anti infection plan adjustment, to assist doctors to develop individualized regimen on the patients. After treatment, the patient''s condition was basically controlled without any adverse drug reactions. Therefore, clinical pharmacists will be prompted when participate in patients''s medication therapy, can combine with the special physiological, pathological state, drug concentration monitoring and clinical response, etc., to assist physicians to optimize medicine treatment, improve the efficacy and safety. |
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| Keywords: | Severe acute pancreatitis Vancomycin Therapeutic drugs concentration monitoring Obesity Augmented renal clearance Pharmaceutical care |
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