| 地奈德乳膏联合多润皮肤护理剂治疗慢性湿疹的疗效观察 |
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| 引用本文： | 陈天柱,潘晓雯,贾天剑.地奈德乳膏联合多润皮肤护理剂治疗慢性湿疹的疗效观察[J].中华全科医学,2016,14(7):1127. |
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| 作者姓名： | 陈天柱 潘晓雯 贾天剑 |
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| 作者单位： | 无锡市疾病预防控制中心, 江苏 无锡, 214023 |
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| 摘 要： | 目的 观察地奈德乳膏联合多润皮肤护理剂治疗慢性湿疹的疗效。 方法 将78例门诊就诊的慢性湿疹患者简单随机抽样分为治疗组和对照组，治疗组42例外用地奈德乳膏(重庆华邦制药有限公司)和多润皮肤护理剂(济南蓝科医学工程有限公司)，每天各2次，对照组36例外用地奈德乳膏，2次/d，2组均使用4周。治疗前后对部位、症状及皮损面积的总积分按EASI评分进行评价。治疗过程中观察并记录药物的不良反应。2个月后对治愈的患者进行复发率的随访。 结果 治疗组42例中痊愈28例，显效10例；对照组36例中痊愈15例，显效9例，2组疗效比较差异有统计学意义(Z=-2.759，P<0.05)。对治愈病例2个月后随访复发率，治疗组28例治愈中有2例复发，复发率为7.1%，对照组15例治愈中有5例复发，复发率为33.3%，2组复发率比较差异有统计学意义(P<0.05)。治疗组与对照组均未见明显不良反应。 结论 地奈德乳膏联合多润皮肤护理剂治疗慢性湿疹有较好疗效，安全性较高。
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| 关 键 词： | 地奈德乳膏 多润皮肤护理剂 慢性湿疹 |
| 收稿时间： | 2015-02-15 |
The curative effect of desonide cream combined with Multi embellish skin care agent for chronic eczema |
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| Affiliation: | Wuxi City Center for Disease Control and Prevention, Wuxi, Jiangsu 214023, China |
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| Abstract: | Objective To evaluate the curative effect of desonide cream combined with Multi embellish skin care agent for chronic eczema. Methods Seventy-eight patients were randomly divided into treatment group and control group.Forty-two cases in treatment group were treated with desonide cream and Multi embellish skin care agent,each twice a day.Thirty-six cases in control group were trated with desonide cream,twice a day,two groups are using 4 weeks.Before and after treatment,the total score of the site,symptoms and skin lesions were evaluated according to EASI score.Adverse drug reactions were observed and recorded during the course of treatment.The recurrence rate of cured cases was assessed after 2 months. Results In the treatment group of 42 cases,28 cases were cured,10 cases had marked effect;In the Control group of 36 cases,15 cases were cured,9 cases had marked effect.Two groups of curative effect comparison difference was statistically significant(Z=-2.759,P<0.05).The recurrence rate of cured cases was assessed after 2 months,In treatment group of 28 cases,2 cases of recurrence,the recurrence rate was 7.1%.In the control group of 15 cases,5 cases of recurrence,the recurrence rate was 33.3%.The recurrence rates in the two groups had statistically significant difference(the use of Fisher's exact probability method,P<0.05).There were no obvious adverse reaction in two groups. Conclusion Desonide cream combined with Multi embellish skin care agent in the treatment of chronic eczema has better curative effect and high safety. |
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