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运动康复对慢性心力衰竭患者的疗效评价
作者姓名:王海如  朱平辉  王军
作者单位:1.南华大学衡阳医学院,湖南 衡阳 421200
基金项目:北京市科学技术委员会:十大疾病科技成果推广应用研究基金资助项目(Z171100001017246)
摘    要:  目的  探讨慢性心力衰竭患者在基础疾病治疗和规范化药物治疗的基础上联合运动康复对患者的临床治疗效果。  方法  入选2020年01月至2021年08月就诊于某医院的CHF患者110例作为研究对象。随机分为对照组(56例)和康复组(54例)。对照组给予标准治疗,康复组在此基础上联合运动康复治疗。2组患者均在入选时和治疗3个月后采集以下指标:AT时VO2 /VO2max、Peak VO2/kg、Peak VO2 /VO2max、VE/VCO2;LVEF、LVEDD、LVESD;NT-ProBNP;生活质量、焦虑、抑郁评分;再住院率。  结果  干预后,康复组患者AT时VO2 /VO2 max、Peak VO2/kg、Peak VO2 /VO2 max、LVEF 均较对照组增高(P < 0.05);康复组VE/VCO2、NT-ProBNP、再住院率、生活质量、焦虑、抑郁评分均较对照组降低(P < 0.05);2组LVEDD、LVESD无明显变化。  结论  心脏运动康复不仅能改善CHF患者的心肺功能指标、心脏泵血功能、血生化指标、焦虑抑郁情绪,提高生存质量、幸福指数、还能降低再住院率。

关 键 词:生活质量    心脏康复    慢性心力衰竭    心肺运动实验
收稿时间:2022-03-16

Effect Evaluation of Exercise Rehabilitation on Patients with Chronic Heart Failure
Affiliation:1.Hengyang Medical College,University of South China,Hengyang Hunan 4212002.Dept. of Cardiology,Changping Teaching Hospital, Capital Medical University,Beijing 102200,China
Abstract:  Objective  To explore the clinical therapeutic effect of chronic heart failure patients on the basis of basic disease treatment and standardized drug treatment combined with exercise rehabilitation.   Methods  A total of 110 CHF patients admitted to a hospital from January 2020 to August 2021 were selected as the research objects. The patients were randomly divided into control group (56 cases) and rehabilitation group (54 cases). The control group was given standardized treatment, and the rehabilitation group was given combined exercise rehabilitation treatment on this basis. In both groups, the following indicators were collected at the time of enrollment and three months after treatment: AT VO2/ VO2max, Peak VO2/kg, Peak VO2/ VO2max, VE/VCO2; LVEF, LVEDD, LVESD; NT - ProBNP numerical; Quality of life, anxiety and depression scores; Readmission rates.   Results  After intervention, the value of VO2/ VO2 Max, Peak VO2/kg, Peak VO2/ VO2 Max and LVEF in the rehabilitation group were all higher than those in the control group (P < 0.05). The VE/VCO2 value, NT-probNP value, re-hospitalization rate, quality of life, anxiety and depression score in the rehabilitation group were lower than those in the control group (P < 0.05). There were no statistically significant differences in LVEDD, LVESD between the two groups.   Conclusion  Cardiac exercise rehabilitation can not only improve the cardiopulmonary function index, cardiac pumping function, blood biochemical index, anxiety, depression mood, improve the quality of life, happiness index, but also reduce the rate of re-hospitalization of CHF patients.
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