| 体检人群非酒精性脂肪性肝病检出率及其危险因素分析 |
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| 引用本文： | 徐伟强,刘淑萍,李潇萌.体检人群非酒精性脂肪性肝病检出率及其危险因素分析[J].实用肝脏病杂志,2023,26(1):35-38. |
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| 作者姓名： | 徐伟强 刘淑萍 李潇萌 |
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| 作者单位： | 066004 河北省秦皇岛市河北港口集团有限公司港口医院急诊科(徐伟强);河北中医学院附属秦皇岛市中医医院脑病二科(刘淑萍);秦皇岛军工医院消化科(李潇萌) |
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| 基金项目： | *秦皇岛市科学技术研究与发展计划自筹经费项目(编号:202101A210) |
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| 摘 要： | 目的 分析体检人群非酒精性脂肪性肝病(NAFLD)流行率及其危险因素。方法 2018年1月～2020年1月我院体检中心接受体检人群1742例，排除干扰因素后，纳入485例，经超声检查诊断NAFLD者78例，非NAFLD者407例。使用CT扫描仪测量腹腔内脏脂肪面积(VAT)和腹壁皮下脂肪面积(SAT)。检测空腹血糖(FPG)等生化指标。应用单因素和多因素Logistic回归分析NAFLD发病的影响因素。结果 NAFLD组高血压、糖尿病和血脂血症患病率分别为29.5%、35.9%和51.3%,显著高于非NAFLD组(分别为18.7%、23.8%和23.6%,P<0.05),BMI、腰围和臀围分别为(25.1±1.)kg/m2、(90.4±6.3)cm和(101.3±8.4)cm,显著高于非NAFLD组【分别为(22.4±1.1)kg/m2、(81.6±5.7)cm和(95.7±6.2)cm,P<0.05】;血清TG、LDL-C和VAT分别为(2.9±0.3)mmol/L、(3.7±0.4)mmol/L和(146.3±12.1)cm<...
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| 关 键 词： | 非酒精性脂肪性肝病 腹腔内脏脂肪面积 危险因素 多因素分析 体检人群 |
| 收稿时间： | 2022-05-15 |
Risk factors of non-alcoholic fatty liver diseases in physical examination individuals |
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| Xu Weiqiang,Liu Shuping,Li Xiaomeng.Risk factors of non-alcoholic fatty liver diseases in physical examination individuals[J].Journal of Clinical Hepatology,2023,26(1):35-38. |
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| Authors: | Xu Weiqiang Liu Shuping Li Xiaomeng |
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| Affiliation: | Emergency Department, Port Hospital, Hebei Port Group Co., Ltd, Qinhuangdao 066004, Hebei Province, China |
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| Abstract: | Objective The aim of this study was to analyze the risk factors of non-alcoholic fatty liver diseases (NAFLD) in physical examination individuals. Methods 1742 persons received physical examination in our hospital between January 2018 and January 2020, and 485 individuals were eligible for this study based on inclusion and exclusion criteria. The NAFLD was found by ultrasonography in 78 cases and not in 407 cases. The visceral adipose tissue (VAT)was obtained by CT scan, and fasting plasma glucose (FPG) and other common blood parameters were assayed. The risk factors for NAFLD was analyzed by univariate and multivariate Logistic regression. Results The incidences of concomitant blood hypertension, diabetes and hyperlipidemia in patients with NAFLD were 29.5%, 35.9% and 51.3%, much higher than 18.7%, 23.8% and 23.6% (P<0.05), the body mass index, waist and hip circumference were (25.1±1.)kg/m2, (90.4±6.3)cm and (101.3±8.4)cm, much higher than (22.4±1.1)kg/m2, (81.6±5.7)cm and (95.7±6.2)cm, respectively, P<0.05] in persons without NAFLD; serum TG, LDL-C and VAT were (2.9±0.3)mmol/L,(3.7±0.4)mmol/L and (146.3±12.1)cm2, significantly higher than (1.6±0.2)mmol/L, (3.1±0.2)mmol/L and (70.5±4.6)cm2, respectively, P<0.05] in persons without NAFLD; serum ALT, FPG and UA levels were (56.6±11.7)u/L, (5.8±0.7)mmol/L and (387.8±36.3)μmol/L, all significantly higher than (32.4±3.1)u/L, (5.1±0.4)mmol/L and (313.6±51.4)μmol/L, respectively, P<0.05] in persons without NAFLD; the multivariate Logistic regression analysis showed that the increased BMI, elevated VAT, concomitant blood hypertension, and elevated serum TG, LDL-C, ALT and UA levels were all the independent risk factors, while the increased serum HDL-C level was the protective factor for the existence of NAFLD. Conclusion The prevalence of NAFLD in physical examination individuals is relative high, and some increased body health, blood and imaging parameters hints its existence, and warrants further check-up. |
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| Keywords: | Non-alcoholic fatty liver diseases Visceral adipose tissue Risk factors Logistic analysis Physical examination |
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