| 2019年沂蒙老区成年人血脂异常流行现状分析 |
| |
| 引用本文： | 杨柳青,蒋克克,肖笑笑,高铭屿.2019年沂蒙老区成年人血脂异常流行现状分析[J].现代预防医学,2022,0(21):3877-3882. |
| |
| 作者姓名： | 杨柳青 蒋克克 肖笑笑 高铭屿 |
| |
| 作者单位： | 临沂市疾病预防控制中心,山东 临沂 276000 |
| |
| 摘 要： | 目的 分析沂蒙老区18岁及以上人群血脂异常流行状况,为心脑血管疾病的防控提供依据。方法 于2019年采用分层随机抽样方法,在全市15个乡镇抽取并调查18岁及以上常住人口4 296人,抽取空腹静脉血5 ml,检测其TC、HDL-C、LDL-C、TG等异常情况。采用多因素logistic回归分析法分析血脂异常相关因素。结果 调查人群高TC血症患病率为9.55%(419例),男女患病率差异无统计学意义(=6.30,P=0.004),东、西部患病率较高(=39.51,P<0.001); 高LDL-C血症患病率为10.51%(458例),男女患病率差异无统计学意义(=0.02,P=0.891),南部患病率较低(=201.40,P<0.001); 低HDL-C血症患病率为29.82%(1 254例),男性患病率显著高于女性(=100.88,P<0.001),南、东、中部患病率较高(=60.82,P<0.001); 高TG血症患病率为16.22%(692例),男性患病率显著高于女性(=16.01,P=0.001),中、南部患病率较高(=6.30,P=0.004); 血脂总异常率为44.23%(1 887例),男性血脂总异常率显著高于女性(=46.98,P<0.001),中、东部异常率较高(=35.91,P<0.001)。除血脂总异常指标(=2.11,P=0.125)外,高TC血症(=10.15,P<0.001)、高LDL-C血症(=12.71,P<0.001)、低HDL-C血症(=7.57,P=0.001)、高TG血症(=6.93,P=0.002)等各项指标不同年龄组人群患病率差异均有显著性统计学意义; 高TC血症(=4.06,P=0.064)、高LDL-C血症(=2.31,P=0.151)、低HDL-C血症(=0.76,P=0.399)、高TG血症(=0.59,P=0.454)、血脂总异常(=0.50,P=0.490)的城乡差异不显著; 高血压(OR=1.44,P<0.001)、糖尿病(OR=1.41,P=0.002)、超重肥胖(OR=2.96,P<0.001)、吸烟(OR=1.62,P<0.001)等多种因素对血脂异常发病的影响具有统计学意义,是血脂异常的危险因素。结论 临沂市成年人血脂异常水平较高,以低HDL-C血症、高TG血症为主。血脂异常的发生与高血压、糖尿病、超重肥胖、吸烟等多种因素有关。
|
| 关 键 词： | 成年人 血脂异常 流行病学研究 |
Prevalence of dyslipidemia among adults in Yimeng revolutionary area, 2019 |
| |
| YANG Liu-qing,JIANG Ke-ke,XIAO Xiao-xiao,GAO Ming-yu.Prevalence of dyslipidemia among adults in Yimeng revolutionary area, 2019[J].Modern Preventive Medicine,2022,0(21):3877-3882. |
| |
| Authors: | YANG Liu-qing JIANG Ke-ke XIAO Xiao-xiao GAO Ming-yu |
| |
| Affiliation: | Linyi Center for Disease Control and Prevention, Linyi, Shandong 276000, China |
| |
| Abstract: | Objective To investigate the prevalence and distribution characteristics of dyslipidemia among adults(aged 18 years and above)in Yimeng revolutionary area,and to provide basis for prevention and control of cardiovascular and cerebrovascular diseases. Methods The level of triglyceride(TG), low density lipoprotein-cholesterol(LDL-C), high density lipoprotein-cholesterol(HDL-C), and total cholesterol(TC)were determined in fasting serum of 5ml venous blood for subjects aged 18 years and above who were selected by stratified random sampling from 15 townships in 2019. Calculate the prevalence of hypercholesterolemia, high blood LDL-C, low blood HDL-C, hypertriglyceridemia and dyslipidemia in population using multivariate regression analysis to analyze the related factors of dyslipidemia. Results The prevalence of hypercholesterolemia was 9.55%(n=419), and there was no significant difference between male and female(=6.30, P=0.004), but high between the East and West(=39.51, P<0.001); The prevalence of high blood LDL-C was 10.51%(n=458), and there was no significant difference between male and female(=0.02, P=0.891), while lower in the South(=201.40, P<0.001); The prevalence of low blood HDL-C was 29.82%(n=1 254), and the prevalence in male was significantly higher than that in female(=100.88, P<0.001), while the prevalence was relatively high in the South, East and middle(=60.82, P<0.001); The prevalence of hypertriglyceridemia was 16.22%(n=692), and the prevalence in male was significantly higher than that in female(=16.01, P=0.001), while the prevalence was relatively high in the middle and South(=6.30, P=0.004); The prevalence of dyslipidemia was 44.23%(n=1 887), and the prevalence in male was significantly higher than that in female(=46.98, P<0.001), while the prevalence was relatively high in the middle and East(=35.91, P<0.001). Except the prevalence of dyslipidemia(=2.11, P=0.125), there were some indicators that had statistically significant differences in the prevalence rate of different age groups, including hypercholesterolemia(=10.15, P<0.001), high blood LDL-C(=12.71, P<0.001), low blood HDL-C(=7.57, P=0.001)and hypertriglyceridemia(=6.93, P=0.002); there were also some indicators that had no significant differences of the prevalence comparing urban and rural areas, including hypercholesterolemia(=4.06, P=0.064), high blood LDL-C(=2.31, P=0.151), low blood HDL-C(=0.76, P=0.399), hypertriglyceridemia(=0.59, P=0.454)and dyslipidemia(=0.50, P=0.490).The effect of hypertension(OR=1.44, P<0.001), diabetes(OR=1.41, P=0.002), overweight and obesity(OR=2.96, P<0.001)on dyslipidemia were statistically significant, hence the risk factors of dyslipidemia. Conclusion Dyslipidemia rate is comparatively high among adults in Linyi, mainly with low blood HDL-C and hypertriglyceridemia. Dyslipidemia is related to hypertension, diabetes, overweight, obesity and smoking. |
| |
| Keywords: | Adult Dyslipidemia Epidemiological studies |
|
| 点击此处可从《现代预防医学》浏览原始摘要信息 |
|
点击此处可从《现代预防医学》下载全文 |
|
