| 儿童青少年体脂肪和瘦体重对心血管危险因素聚集的交互作用 |
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| 引用本文： | 董洋洋,蔡蓉蓉,白玲,周金玉,贾磊娜,丁文清.儿童青少年体脂肪和瘦体重对心血管危险因素聚集的交互作用[J].中国学校卫生,2021,42(10):1555-1559. |
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| 作者姓名： | 董洋洋 蔡蓉蓉 白玲 周金玉 贾磊娜 丁文清 |
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| 作者单位： | 1.宁夏医科大学公共卫生与管理学院，银川 750004 |
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| 基金项目： | 国家自然科学基金项目81660565 |
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| 摘 要： | 目的 分析银川市儿童青少年体脂肪(FM)和瘦体重(FFM)对心血管危险因素(CVRFs)聚集的交互作用，为预防儿童青少年心血管疾病的发生提供科学依据。 方法 于2017—2020年使用整群抽样的方法选取银川市1 822名12~18岁儿童青少年，进行问卷调查、体格检查、体成分测定和实验室检测。采用二分类Logistic回归分析FM、FFM与CVRFs聚集的关系，并分析交互作用。 结果 调整性别和年龄后，高FM低FFM组和高FM高FFM组发生CVRFs聚集个数至少为1(CVRFs≥1)的风险是低FM低FFM组的2.01(95%CI=1.46~2.77)、3.64(95%CI=2.66~4.98)倍，CVRFs聚集个数至少为2(CVRFs≥2)的风险分别为1.67(95%CI=1.06~2.63)、4.20(95%CI=2.76~6.38)倍(P值均 < 0.05)；FM和FFM存在相乘交互作用，增加CVRFs≥1和CVRFs≥2的风险，调整后的OR值(95%CI)值分别为1.58(1.04~2.40)、1.95(1.12~3.42)(P值均 < 0.05)。 结论 高水平体脂肪和瘦体重对心血管危险因素聚集有相加和相乘交互作用, 增加了心血管危险因素聚集的风险。
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| 关 键 词： | 脂肪组织 体重 心血管系统 回归分析 儿童 青少年 |
| 收稿时间： | 2021-03-12 |
Interaction between fat mass and fat free mass on the aggregation of cardiovascular disease risk factors among children and adolescents |
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| Affiliation: | 1.School of Public Health and Management, Ningxia Medical University, Yinchuan(750004), China |
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| Abstract: | Objective To analyze the interaction of fat mass (FM) and fat free mass (FFM) on the aggregation of cardiovascular disease risk factors (CVRFs) among children and adolescents in Yinchuan City, China, so as to provide scientific basis for the prevention of CVRFs and cardiovascular disease in children and adolescents. Methods A total of 1 822 children and adolescents aged 12 to 18 years in Yinchuan City were randomly selected for questionnaire survey, physical examination, body composition assessment and laboratory tests, through a cluster sampling method from 2017 to 2020. Binary Logistic regression was used to analyze the relationship between FM, FFM and the aggregation of CVRFs, and their interaction was analyzed. Results After adjusting for sex and age, the risk of having CVRFs aggregation ≥1 in high FM and low FFM group and high FM and high FFM group was 2.01(95%CI=1.46-2.77) and 3.64(95%CI=2.66-4.98) times higher than that in low FM and low FFM group, and the risk of having CVRFs aggregation ≥2 was 1.67(95%CI=1.06-2.63) and 4.20 (95%CI=2.76-6.38) times, respectively(P < 0.05). There was a multiplicative interaction between FM and FFM, which increased the risk of CVRFs aggregration ≥1 and ≥2. The adjusted OR and 95%CI were 1.58(1.04-2.40) and 1.95(1.12-3.42), respectively(P < 0.05). Conclusion The results indicated the additive and multiplicative interactions between high levels of fat mass and fat free mass on the aggregation of cardiovascular risk factors, which increased the risk of aggregation of cardiovascular risk factors. |
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