| 男性乳腺癌临床病理特征及预后相关因素的回顾性分析 |
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| 引用本文： | 师 弘,马 鑫,彭书甲,刘 娟,王 伟.男性乳腺癌临床病理特征及预后相关因素的回顾性分析[J].现代肿瘤医学,2021,0(15):2629-2632. |
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| 作者姓名： | 师 弘 马 鑫 彭书甲 刘 娟 王 伟 |
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| 作者单位： | 1.空军军医大学唐都医院肿瘤科；3.普通外科，陕西 西安 710038;
2.空军第九八六医院第六门诊部，陕西 西安 710032;
4.兵器工业五二一医院肿瘤科，陕西 西安 710065 |
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| 基金项目： | National Natural Science Foundation of China(No.81302284）；国家自然科学基金（编号:81302284） |
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| 摘 要： | 目的:采用回顾性分析研究，探讨男性乳腺癌(male breast cancer,MBC)患者的临床流行病学特征及预后相关因素。方法:通过病例检索系统，统计2009年01月至2019年12月空军军医大学（原第四军医大学）唐都医院收治的“男性乳腺癌”共计28例纳入本研究，对纳入研究的乳腺癌患者的首发症状、临床特征、病理分类、治疗方式、预后等流行病学特征进行分析。结果:本研究共计纳入28例MBC患者，中位发病年龄为66岁(43~91岁)。有乳腺癌家族史有2例，约占7.14%，临床分期为Ⅰ-Ⅱ期的患者有8例，Ⅲ-Ⅳ期的患者有20例。本研究中22例(78.57%)患者接受了手术治疗，20例(71.43%)患者接受了全身静脉化疗，15例（53.57%）患者接受了放射治疗，还有19例（67.86%）患者接受了内分泌治疗。生存分析结果显示临床分期及肿瘤组织病理学分级为男性乳腺癌患者的独立预后影响因素。结论:本文对男性乳腺癌的临床特点及预后相关因素流行病学特征进行分析。有利于对减少临床误诊及进一步进行个体化治疗提供依据。
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| 关 键 词： | 男性乳腺癌 临床特点 预后因素 |
A retrospective analysis of the clinical characteristics and prognostics factors in male breast cancer |
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| SHI Hong,MA Xin,PENG Shujia,LIU Juan,WANG Wei.A retrospective analysis of the clinical characteristics and prognostics factors in male breast cancer[J].Journal of Modern Oncology,2021,0(15):2629-2632. |
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| Authors: | SHI Hong MA Xin PENG Shujia LIU Juan WANG Wei |
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| Affiliation: | 1.Department of Oncology;3Department of General Surgery,the Second Affiliated Hospital of Air Force Medical University,Shaanxi Xi'an 710038,China;2.the Sixth Outpatient Department,986 Hospital of Air Force,Shaanxi Xi'an 710032,China;4Department of Oncology,521 Hospital of Ordnance Industry,Shaanxi Xi'an 710065,China. |
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| Abstract: | Objective:To investigate clinical characteristics of male breast cancer(MBC) to provide reference for prevention and individual therapy in MBC.Methods:The clinical data in breast cancer patients was admitted from January 2009 to December 2019 in Tangdu Hospital were reviewed.28 patients of MBC were involved in this study.The research on into starting symptoms of breast cancer patients,clinical features,pathological classification,treatment,prognosis and so on epidemiological characteristics were analyzed.Results:The middle on diagnose age of was 66(43~91) years old.There were two cases with family history of breast cancer,accounting for about 7.14%.For diagnosis of clinical stage,8 patients were in stage I to II,20 patients were in stage III-IV．24 patients were hormone receptor positive．Totally，22 patients(78.57%) received surgery．20 patients received chemotherapy，15 patients received radiotherapy．19 patients received endocrine therapy．Survial analysis showed that stage at diagnosis and histological grade were found to be independent predictors in MBC.Conclusion:The mechanism of MBC should be studied further in order to reduce the misdiagnosis and the risk for MBC.MBC is a rare cancer in male,and most patients are diagnosed older and at advanced clinical stage.For the better survival in MBC patients,early diagnosis,treatment and more intensive surveillance are important.The diagnosis and treatment of male breast cancer remains to be further studied． |
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| Keywords: | male breast cancer clinical epidemiology prognostic factors |
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