| 2007～2008年广西苍梧县石桥镇鼻咽癌普查结果初步分析* |
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| 引用本文： | 兰桂萍,林辉,廖建,司勇锋,邓卓霞,张政,周日晶,钟建明,黎炎成,周志刚.2007～2008年广西苍梧县石桥镇鼻咽癌普查结果初步分析*[J].中国肿瘤临床,2010,37(10):576-578. |
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| 作者姓名： | 兰桂萍 林辉 廖建 司勇锋 邓卓霞 张政 周日晶 钟建明 黎炎成 周志刚 |
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| 作者单位： | 作者单位:广西壮族自治区人民医院鼻咽癌研究所(南宁市530021);①广西壮族自治区苍梧县鼻咽癌防治所 |
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| 基金项目： | 广西壮族自治区卫生厅资助 |
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| 摘 要： | 目的:通过鼻咽癌普查了解广西苍梧县高发区鼻咽癌流行状况，探讨可持续发展的鼻咽癌早诊早治普查模式。方法:于2007年6 月～2008年12月在广西苍梧县石桥镇鼻咽癌现场进行鼻咽癌普查。在鼻咽癌现场建立人口档案；进行流行病学调查；参加普查者均进行头颈部检查及间接鼻咽镜检查，鼻咽癌EB病毒壳抗原IgA 抗体（IgA/VCA ）和早期抗原IgA 抗体（IgA/EA）血清学检测；检查结果可疑和血清学结果阳性者均进行鼻内镜检查；鼻咽部可疑病变者行活组织病理检查；鼻咽癌普查结果均输入电脑，应用EpiData3.1 建立数据库。结果:鼻咽癌现场筛查人群8 458 人，其中EB病毒IgA/VCA 阳性522 例，EB病毒IgA/EA阳性28例，进行鼻内镜检查410 例，鼻咽部活组织检查45例，检出鼻咽癌12例，其中早期鼻咽癌6 例，接受治疗11例。鼻咽癌人群检出率141.87/10 5，早诊率50% ，治疗率91.6% 。结论:广西苍梧县鼻咽癌早诊早治普查方案是鼻咽癌防治的重要策略之一，而鼻咽癌早诊早治普查工作应持续发展。
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| 关 键 词： | 鼻咽癌 血清学检测 普查 |
| 收稿时间： | 2009-08-11 |
Mass Screening for Nasopharyngeal Carcinoma in Shiqiao Town of Cangwu County in Guangxi from 2007 to 2008 Improves Early Diagnosis and Treatment |
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| LAN Guiping,LIN Hui,LIAO Jian,SI Yongfeng,DENG Zhuoxia,ZHANG Zheng,ZHOU Rijing,ZHONG Jianming,LI Yancheng,ZHOU Zhigang.Mass Screening for Nasopharyngeal Carcinoma in Shiqiao Town of Cangwu County in Guangxi from 2007 to 2008 Improves Early Diagnosis and Treatment[J].Chinese Journal of Clinical Oncology,2010,37(10):576-578. |
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| Authors: | LAN Guiping LIN Hui LIAO Jian SI Yongfeng DENG Zhuoxia ZHANG Zheng ZHOU Rijing ZHONG Jianming LI Yancheng ZHOU Zhigang |
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| Affiliation: | 1Nasopharyngeal Carcinoma Institute, People ’s Hospital of Guangxi Zhuang Autonomous Region, Nanning,530021,China |
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| Abstract: | Objective: To investigate the epidemic status of nasopharyngeal carcinoma in high areas in Cangwu town in Guangxi by mass screening. To explore the sustainable development of massing screening for nasopharyngeal carcino -ma to improve early diagnosis and treatment. Methods:From 2007-2008，the mass screening of nasopharyngeal carcino-ma was carried out in Shiqiao town. Population archives were established and evolved during the epidemiological investiga-tion. All the cases of screening had a head and neck examination combined with indirect pharyngorhinoscopy, IgA antibod -ies to Epstein-Barr virus capsid antigen (IgA/VCA) and IgA antibodies to Epstein-Barr virus early antigen (IgA/EA) serology testing. The cases with a positive serological result and questionable examination received nasal endoscopy. Questionable pharynx nasalis tissue was collected and checked. The EpiData 3.1 database was used to track all the dates of the mass screening. Results:A total of 8458cases were screened for nasopharyngeal carcinoma. Of these,522 cases were positive for the Epstein-Barr virus IgA/VCA , and 28cases were positive for the Epstein-Barr virus IgA/EA. Nasal endoscopy was performed on 410 cases. Biopsies were collected on 45 cases. Nasopharyngeal carcinoma was found in 12 cases, of which 6 were early nasopharyngeal carcinoma. Eleven cases accepted treatment. The prevalence of nasopharyngeal carci -noma was 141 .87/10 5 . The early diagnosis rate was 50%. The treatment rate was91.6%.Conclusion:The early diagnosis and early treatment screening scheme in Cangwu county is one of the main strategies of prevention and cure for nasopha-ryngeal carcinoma. The work of mass screening for nasopharyngeal carcinoma has been shown successful and should be continued. |
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