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糖尿病患者脂联素水平与左心室功能改变的相关性研究
引用本文:王雪,展英华,张梅.糖尿病患者脂联素水平与左心室功能改变的相关性研究[J].中华医学超声杂志,2011,8(2):52-54.
作者姓名:王雪  展英华  张梅
作者单位:山东省临沂市人民医院超声诊疗中心,276003
摘    要:目的观察糖尿病患者的血清脂联素水平,探讨糖尿病患者心功能早期改变与脂联素之间关系。方法选取2型糖尿病患者60例,对照组60例,应用经胸二维超声、组织多普勒超声、实时三维超声心动图获取受检者心脏左心室舒张、收缩功能参数,分别与其血清脂联素测值做相关分析。结果糖尿病患者与对照组相比,血清脂联素降低(P<0.01);二尖瓣口舒张早期前向血流峰值流速(ME)降低,舒张晚期前向血流峰值流速(MA)升高,ME/MA<1,差异有统计学意义(P<0.05);二尖瓣环外侧壁舒张早期运动峰值速度(ME’)降低,舒张晚期运动峰值速度(MA’)升高,ME’/MA’<1,ME/ME’比值增大,差异有统计学意义(P<0.05)。血清脂联素与ME/MA、ME’/MA’呈正相关(r分别为0.368,0.365,P<0.05);与ME/ME’比值呈负相关(r=-0.347,P<0.05)。结论糖尿病患者左心室舒张功能受损,且与血清脂联素水平密切相关。

关 键 词:超声心动描记术  左心室功能  糖尿病  脂联素

The relevance study among the levels of serum adiponectin and the changes of left cardiac function in patients with diabetes
WANG Xue,ZHAN Ying-hua,ZHANG Mei.The relevance study among the levels of serum adiponectin and the changes of left cardiac function in patients with diabetes[J].Chinese Journal of Medical Ultrasound,2011,8(2):52-54.
Authors:WANG Xue  ZHAN Ying-hua  ZHANG Mei
Affiliation:WANG Xue,ZHAN Ying-hua,ZHANG Mei. Department of Ultrasonography,Linyi People's Hospital,Shandong Linyi 276003,China
Abstract:Objective To evaluate relationship among the levels of serum adiponectin and early changes of cardiac function in patients with type 2 diabetes. Methods A total of 60 cases with type 2 diabetes and 60 healthy subjects were included. The correlation between left ventricular function and the level of serum adiponectin was analyzed,which was obtained by two-dimensional tissue Doppler and three-dimensional echocardiography examination in all subjects. Results Compared with the healthy group,the levels of serum ...
Keywords:Ultrasonography  Left ventricular function  Diabetes mellitus  Adiponectin  
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