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TNF-α拮抗剂治疗复发性疱疹样脓疱病一例
引用本文:王娟娟,苏玉华,丁瑜洁,冷红,季江,施辛.TNF-α拮抗剂治疗复发性疱疹样脓疱病一例[J].中国麻风皮肤病杂志,2020,36(3):171-173.
作者姓名:王娟娟  苏玉华  丁瑜洁  冷红  季江  施辛
作者单位:苏州大学附属第二医院皮肤科,苏州,215004
基金项目:国自然青年科学基金项目(编号:81803127);苏州市民生科技项目(编号:SS201643);苏州市科技发展计划(编号:SYS2018056)。
摘    要:患者,女,31岁。妊娠期反复脓疱加重1个月。患者8年前妊娠期曾全身出现红斑、脓疱,产后皮损自行消失。根据患者既往病史、症状、体征及辅助检查,诊断“疱疹样脓疱病”,入院后予TNF-α拮抗剂皮下注射,辅以复方甘草酸苷、阿奇霉素抗炎及外用药治疗,1周后患者皮疹明显好转出院。

关 键 词:疱疹样脓疱病  TNF-α拮抗剂  

Recurrent impetigo herpetiformis treated with TNF-α antagonist:a case report
WANG Juanjuan,SU Yuhua,DING Yujie,LENG Hong,JI Jiang,SHI Xin.Recurrent impetigo herpetiformis treated with TNF-α antagonist:a case report[J].China Journal of Leprosy and Skin Diseases,2020,36(3):171-173.
Authors:WANG Juanjuan  SU Yuhua  DING Yujie  LENG Hong  JI Jiang  SHI Xin
Affiliation:Department of Dermatology, the Second Affiliated Hospital of Soochow University, Suzhou 215004, China
Abstract:A 31-years-old female patient presented with widespread erythema and pustules during pregnancy,aggravating for 1 month.The patient had a history of the similar symptoms during pregnancy before 8 years ago and the lesions disappeared spontaneously after delivery.According to the patient s previous medical history,symptoms,physical signs and laboratory examination,the diagnosis of“impetigo herpetiformis”was made.The patient was injected subcutaneously with TNF-α antagonist,supplemented with Minol,Azithromycin anti-inflammatory and topical medication.The lesion was significantly improved after one week treatment.
Keywords:impetigo herpetiformis  TNF-α antagonist
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