| 碳青霉烯类治疗铜绿假单胞菌肺炎的临床效果分析 |
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| 引用本文： | 李绪定.碳青霉烯类治疗铜绿假单胞菌肺炎的临床效果分析[J].医学信息,2018,0(13):134-136. |
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| 作者姓名： | 李绪定 |
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| 作者单位： | 湖北省当阳市人民医院呼吸内科，湖北 当阳 444100 |
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| 摘 要： | 目的 探究碳青霉烯类治疗铜绿假单胞菌肺炎的效果。方法 选取2017年1月~2018年1月收治的86例PA肺炎患者临床资料进行分析，随机分为对照组和研究组，每组43例。对照组行头孢哌酮钠舒巴坦钠治疗，研究组行碳青霉烯类双联法治疗，比较两组肺功能（FEV1/FVC、FEV1）、实验室指标（CRP、PCT、WBC）及生活质量（SGRQ评分）。结果 两组患者治疗后FEV1/FVC、FEV1水平均优于治疗前，且研究组改善幅度大于对照组，统计学意义显著（P＜0.01）。研究组治疗后实验室各指标水平均优于治疗前，且优于对照组，统计学意义显著（P＜0.01）。治疗后，研究组SGRQ评分为（30.87±3.55）分，低于对照组的（40.54±4.36）分，统计学意义显著（P＜0.01）。结论 碳青霉烯类治疗铜绿假单胞菌肺炎，可有效改善患者肺功能，减轻炎症反应，提高生活质量。
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| 关 键 词： | 碳青霉烯类 铜绿假单胞菌 肺炎 |
Clinical Effect of Carbapenem in the Treatment of Pseudomonas Aeruginosa Pneumonia |
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| LI Xu-ding.Clinical Effect of Carbapenem in the Treatment of Pseudomonas Aeruginosa Pneumonia[J].Medical Information,2018,0(13):134-136. |
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| Authors: | LI Xu-ding |
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| Affiliation: | Department of Respiratory Medicine,Dangyang People’s Hospital,Dangyang 444100,Hubei,China |
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| Abstract: | Abstract:Objective To explore the effect of carbapenem in the treatment of Pseudomonas aeruginosa pneumonia.Methods 86 patients with Pseudomonas aeruginosa pneumonia admitted from January 2017 to January 2018 were randomly divided into control group(n=43)and study group(n=43).The control group was treated with cefoperazone sodium sulbactam sodium,the study group was treated with carbapenem double therapy,and the pulmonary function (FEV1/FVCU,FEV1),laboratory index(CRP,PCT,WBC)and quality of life(SGRQ score)were compared between the two groups.Results The level of FEV1/FVC,FEV1 in the two groups was better than that before treatment,and the improvement in the study group was greater than that in the control group,there was significant statistical significance(P<0.01).The level of the indicators in the laboratory after treatment was better than that before treatment,and it was better than the control group,and the statistical significance was significant(P<0.01).After treatment,the SGRQ score of the study group was(30.8±3.55),which was lower than that of the control group(40.54±4.36),and the statistical significance was significant(P<0.01).Conclusion Carbapenem can effectively improve pulmonary function,alleviate inflammatory reaction and improve quality of life in patients with Pseudomonas aeruginosa pneumonia. |
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| Keywords: | Key words:Carbapenem Pseudomonas aeruginosa Pneumonia |
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