| 高磷血症维持性血液透析患者的临床分析 |
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| 引用本文： | 秦纪平,张翀,常娟,汤志奇,茅宇烽,施莲珍.高磷血症维持性血液透析患者的临床分析[J].现代生物医学进展,2011,11(22):4276-4278. |
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| 作者姓名： | 秦纪平 张翀 常娟 汤志奇 茅宇烽 施莲珍 |
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| 作者单位： | 上海市交通大学医学院附属新华医院(崇明)肾内科 上海 202150 |
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| 摘 要： | 目的:比较不同血磷水平的维持性血液透析的尿毒症患者的临床表现和实验室指标,探讨其临床意义。方法:选择上海交通大学医学院附属新华医院(崇明)肾内科28例高血磷(SP>1.6mmol/L)的维持性血液透析患者为病例组,30例血磷正常(SP≤1.6mmol/L)维持性血液透析患者为对照组,比较两组患者的原发病组成,年龄,性别,透析龄,皮肤瘙痒发生率,腰背痛发生率,血钙,血碳酸氢根,血红蛋白,红细胞压积,血碱性磷酸酶,肾功能,血浆白蛋白水平及左心室肥厚发生率。结果:病例组与对照组在原发病组成,年龄(43.2±9.8岁vs 40.5±12.2岁),男女性别比例(16/12 vs.17/13),透析龄(32.56±6.71月vs.35.43±5.82月)等方面无显著性差异(P>0.05),有可比性,在血红蛋白(83.22±6.71g/L vs 103.36±5.84g/L),红细胞压积(24.83±1.92%vs.30.76±1.52%),血钙(1.71±0.16mmol/L vs.2.23±0.21 mmol/L),血碳酸氢根(14.2±3.1mmol/L vs 20.6±4.9 mmol/L),血碱性磷酸酶(124.26±16.33U/L vs.61.47±14.91 U/L),皮肤瘙痒发生率(22/28 vs.7/30),腰背痛发生率(19/28 vs.6/30),左心室肥厚发生率(20/28 vs 12/30),有显著性差异(P<0.05),肌酐(956±142mmol/L vs.923±156 mmol/L),尿素氮(23.1±6.3mmol/L vs.24.8±8.9mmol/L),血浆白蛋白(30.5±3.8g/L vs.31.2±2.9g/L),无显著性差异(P>0.05)。结论:伴有高磷血症的维持性血液透析患者与血磷正常的患者相比,血碱性磷酸酶,皮肤瘙痒发生率,腰背痛发生率及左心室肥厚发生率较高,而血钙,血碳酸氢根,血红蛋白及红细胞压积较低,有一定差异。
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| 关 键 词： | 高磷血症 继发性甲状旁腺功能亢进 血液透析 |
The Clinical Analysis of Hyperphosphatemia in Maintenance Hemodialysis Patients |
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| QIN Ji-Ping,ZHANG Chong,CHANG Juan,TANG Zhi-Qi,MAO Yu-Feng,SHILian-Zhen.The Clinical Analysis of Hyperphosphatemia in Maintenance Hemodialysis Patients[J].Progress in Modern Biomedicine,2011,11(22):4276-4278. |
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| Authors: | QIN Ji-Ping ZHANG Chong CHANG Juan TANG Zhi-Qi MAO Yu-Feng SHILian-Zhen |
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| Affiliation: | QIN Ji-Ping,ZHANG Chong,CHANG Juan,TANGZhi-Qi,MAOYu-Feng,SHILian-Zhen(Department of Nephrology,Xinhua Hospital affiliated to Shanghai Jiaotong University School of Medicine(ChongMing) 202150) |
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| Abstract: | Objective: To compare the clinical feature and laboratory examination indexes of different serum phosphorus levels in uremia patients treated with maintenance hemodialysis and explore its clinical significance.Methods:According to the serum phosphorus levels,58 maintenance hemodialysis patients from department of nephrology,Xinghua Hospital Affiliated to Shanghai Jiaotong Universi-ty School of Medicine were divided into two groups,including 28 cases of case group(SP>1.6mmol/L) and 30 cases of control group(... |
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| Keywords: | Hyperphosphatemia Secondary hyperparathyroidism Hemodialysis |
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