| Ratio of hydantoinase and N-carbamoylase: key to preparation of D-amino acid from 5-monosubstituted hydantoin |
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| 作者姓名： | 姚忠 竺凯 周华 韦萍 欧阳平凯 |
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| 作者单位： | 南京工业大学制药与生命科学学院 |
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| 基金项目： | 国家重点基础研究发展计划(973计划) |
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| 摘 要： | The optically active D-amino areas are valuable intermediates for the production of semi-synthetic antibiotics; hormones, bioactive peptides, and 5-monosubstituted hydantoins are important precursors for the commercial production of aminoacids. Two enzymes are involved in the stereo-selective deavage of D, L-S-monosubstituted hydantoins and N-carbamoyl amino acid (Fig. 1).
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| 关 键 词： | 取代 海因酶 制备 酸水解 氨基酸 比例 |
| 收稿时间： | 2004-8-2 |
| 修稿时间： | 2004-10-5
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Ratio of hydantoinase and N-carbamoylase: key to preparation of D-amino acid from 5-monosubstituted hydantoin |
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| YAO Zhong,ZHU Kai,ZHOU Hua,WEI Ping,Ouyang Pingkai.Ratio of hydantoinase and N-carbamoylase: key to preparation of D-amino acid from 5-monosubstituted hydantoin[J].Journal of Chemical Industry and Engineering(China),2005,56(1):148-151. |
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| Authors: | YAO Zhong ZHU Kai ZHOU Hua WEI Ping Ouyang Pingkai |
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| Abstract: | |
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| Keywords: | ratio hydantoinase carbamoylase D-amino acid preparation Burkholderia cepecia 1003 |
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