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Bioactive compounds and advanced processing technology: Phaleria macrocarpa (sheff.) Boerl,a review
Authors:Mst Sabina Easmin  Md Zaidul Islam Sarker  Sahena Ferdosh  Siti Hadijah Shamsudin  Kamaruzzaman Bin Yunus  Md Salim Uddin  Md Moklesur Rahman Sarker  Md Jahurul Haque Akanda  Md Sohrab Hossain  HPS Abdul Khalil
Affiliation:1. Faculty of Pharmacy, International Islamic University Malaysia, Kuantan, Pahang, Malaysia;2. Faculty of Science, International Islamic University Malaysia, Kuantan, Pahang, Malaysia;3. Clinical Investigation Centre, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia;4. Department of Food Science and Nutrition, Faculty of Applied Sciences, UCSI University, Kuala Lumpur, Malaysia;5. School of Industrial Technology, Universiti Sains Malaysia, Pulau Pinang, Malaysia
Abstract:Recent technological advances and the development of new methods has provided an opportunity to obtain highly purified natural bioactive compound extracts with potential for the treatment and prevention of human diseases. The use of hazardous and toxic solvents for the extraction and processing of bioactive compounds from plant materials is considered a problem for health, safety and environmental pollution. Advanced technology aims to increase production of the desired compounds and find an alternative to using toxic solvents in the extraction of bioactive compounds from plant materials. The ever growing interest in plant bioactive compounds and today's concerns about environment issues have led to an increased need for an efficient and green extraction method. This review is focused on the extraction of bioactive compounds from plants using advanced and environment‐friendly methods such as supercritical fluid extraction, microwave‐assisted extraction, ultrasound‐assisted extraction and similar techniques that can extract rapidly and free from organic residues. An updated overview of the bioactive compounds present in the plant Phaleria macrocarpa and its extraction, fractionation, purification and isolation is provided. The advantages and disadvantages of both conventional and non‐conventional extraction methods are also discussed in this review. © 2014 Society of Chemical Industry
Keywords:medicinal plant  Phaleria macrocarpa  extraction of bioactive compounds  conventional extraction method  non‐conventional extraction method
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