| Mina53基因与肿瘤的研究进展 |
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| 引用本文： | 邱镜丹,李 荣,王建东.Mina53基因与肿瘤的研究进展[J].现代肿瘤医学,2015,0(11):1624-1627. |
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| 作者姓名： | 邱镜丹 李 荣 王建东 |
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| 作者单位： | 解放军总医院普通外科，北京 100853 |
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| 基金项目： | 北京市自然科学基金资助项目（编号:7142151） |
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| 摘 要： | Mina53是近年发现的一个新基因，是对调控细胞增殖分化起关键作用的原癌基因C-myc下游的一个直接靶基因。Mina53对细胞增殖有重要作用。近年来多项研究证实Mina53基因表达异常与多种肿瘤的发生、发展及预后密切相关。对于Mina53基因的深入研究有助于进一步揭示肿瘤的本质，为辅助诊断和指导治疗提供新靶点。
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| 关 键 词： | Mina53 基因 肿瘤 |
Progress of Mina53 gene in cancer |
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| Qiu Jingdan,Li Rong,Wang Jiandong.Progress of Mina53 gene in cancer[J].Journal of Modern Oncology,2015,0(11):1624-1627. |
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| Authors: | Qiu Jingdan Li Rong Wang Jiandong |
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| Affiliation: | Department of General Surgery，The Chinese PLA General Hospital，Beijing 100853，China. |
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| Abstract: | Myc induced nuclear antigen-mina53(Mina53) is a newly discovered gene，which is the direct target gene of c-Myc.Mina53 plays a role in mammalian cell proliferation.Many studies have indicated that Mina53 gene highly expressed in many tumor tissues，which suggests that the abnormal expression of the Mina53 gene may closely associate with the development，progression and prognosis of the tumors.Studies on Mina53 gene will help revealing the essence of tumors and provide a new target for diagnosis and treatment. |
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| Keywords: | Mina53 gene neoplasms |
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