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青春期前生活方式对儿童血压偏高影响的累积效应分析
引用本文:李艳辉,高迪,陈曼曼,马莹,陈力,董彦会,宋逸,马军.青春期前生活方式对儿童血压偏高影响的累积效应分析[J].中国学校卫生,2021,42(4):489.
作者姓名:李艳辉  高迪  陈曼曼  马莹  陈力  董彦会  宋逸  马军
作者单位:北京大学公共卫生学院/儿童青少年卫生研究所,北京 100191
基金项目:国家自然科学基金项目81673192博士后科学基金项目BX20200019博士后科学基金项目2020M680266
摘    要:  目的  分析青春期前生活方式对儿童血压偏高检出率和新发率影响的累积作用,为儿童血压偏高的早期干预提供依据。  方法  2017年在福建省厦门市4所九年一贯制学校建立青春期发育研究队列,对所有符合纳入标准的二、三年级女生和三、四年级男生进行体格检查和问卷调查。随访2年,选择2017和2019年数据完整的1 316名学生为研究对象。根据2017年基线调查结果评估青春期前生活方式状况。根据2019年血压水平进行血压偏高检出率和新发率的判定。调整混杂因素后采用Logistic回归模型,分析健康生活方式对血压偏高新发率和血压偏高检出率的影响。  结果  2017和2019年血压偏高检出率分别为25.0%和23.3%,血压偏高新发率为18.9%。具备健康生活方式的儿童血压偏高新发率和检出率偏低。Logistic回归分析结果显示,儿童满足健康生活方式因素越多,血压偏高检出率的风险越小(P < 0.05)。与满足0~2个健康生活方式因素学生相比,满足4~5个健康生活方式因素的学生血压偏高检出率低(OR=0.52, 95%CI=0.30~0.90),血压偏高新发率低(RR=0.60,95%CI=0.29~1.22)。其中,超重肥胖学生血压偏高检出率风险明显更低(OR=0.29, 95%CI=0.10~0.81)。  结论  儿童青春期前生活方式对血压偏高检出率具有累积作用,维持健康生活方式对降低血压偏高风险具有积极作用,超重肥胖儿童采取综合的健康生活方式获益更大。

关 键 词:生活方式    血压    患病率    回归分析    儿童
收稿时间:2020-12-11

Cumulative influence of preadolescent lifestyles on the prevalence of elevated blood pressure among children
Affiliation:Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing(100191), China
Abstract:  Objective  To analyze the cumulative effect of preadolescent lifestyles on the prevalence and incidence of elevated blood pressure (EBP) in children, and to provide evidence for early hypertensive intervention.  Methods  In 2017, a cohort study on pubertal development was conducted in Xiamen, Fujian Province. Participants underwent a physical examination and questionnaire survey. Between 2017 and 2019, this study carried out a 2-year follow-up of 1 316 students whose complete data were obtained. Preadolescent lifestyles were assessed by referring to baseline survey results obtained in 2017, and the prevalence and incidence of EBP were determined according to blood pressure levels that were determined in 2019. The logistic regression model was used to analyze the influence of healthy lifestyles on the prevalence and incidence of EBP after adjusted for confounding factors.  Results  The prevalence of EBP in 2017 and 2019 was 25.0% and 23.3%, respectively, and its incidence was 18.9% after the 2-year follow-up. Children with a healthy lifestyle had a lower prevalence and incidence of EBP. The regression analysis showed that children who have more healthy lifestyle factors were at a lower risk of EBP (P < 0.05). Compared with students with 0-2 healthy lifestyle factors, the OR value of EBP prevalence was 0.52 (95%CI=0.30-0.90) and the RR value of EBP incidence was 0.60(95%CI=0.29-1.22) in children with 4-5 healthy lifestyle factors. Among them, children who were overweight or obese were at a significantly lower risk of EBP prevalence (OR=0.29, 95%CI=0.10-0.81).  Conclusion  Preadolescent lifestyles seemed to have a cumulative effect on the occurrence of EBP. Maintaining a healthy lifestyle had a positive effect on reducing the risk of EBP, particularly in overweight and obese children, and this was due to their adoption of a comprehensive healthy lifestyle.
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