| 食管胸中段癌三维适形放疗中呼吸运动导致靶区移位的研究 |
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| 引用本文： | 霍俊杰,乔学英,曹彦坤,周志国,宋玉芝,迟子锋,刘欣,王静.食管胸中段癌三维适形放疗中呼吸运动导致靶区移位的研究[J].中华放射医学与防护杂志,2009,30(6):295-298. |
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| 作者姓名： | 霍俊杰 乔学英 曹彦坤 周志国 宋玉芝 迟子锋 刘欣 王静 |
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| 作者单位： | 邢台医学高等专科学校;河北医科大学第四医院放疗科,石家庄,050011; |
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| 基金项目： | 河北省卫生厅医学科学研究重点课题河北省普通高校强势特色学科资助项目 |
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| 摘 要： | Objective To evaluate the respiration-induced target volume motion in 3D-CRT for mid-thoracic esophageal carcinoma in order to guide the radiation oncologist to choose the expansion margin for ITV.Methods Ten patients with mid-thoracic esophageal carcinoma were scanned by multi-spiral CT simulator respectively in free breathing(FB),breath.hold after normal inspiration and expiration(IBH and EBH)with the same scanning range.Then the CT images of three series were transfefred to the treatment planning system.The target volume was outlined following the same standard.The motion of the center point of GTV,the center point of each slice of GTV and the edge of the GTV in selected slice were measured respectively to obtain the comprehensive value of GTV motion。in order to find the appropriate IM value according to the 95％confidence interval of the GTV motion.Results ①The GTV motion between IBH and EBH was(0.19±0.16)cm in the left.right direction,(0.54±0.19)cm in the cranial and caudal irection.and(0.16±0.14)cm in anterior.posterior directions for the center of GTV,.For the center point of each slice of GTV.they ere(0.19±0.15)cm,(0.54±0.16)cm,(0.16±0.13)cm in three directions above.respectively.For the edge of the GTV in selected slice.they were(0.26±0.19)cm,(0.54±0.18)cm,(0.24±0.19)cm,respectively.The comprehensive value of GTV motion between IBH and EBH was(0.23±0.17)cm,(0.54±0.17)cm,(0.21±0.17)cm.respectively.The 95％confidence interval was 0.21-0.25 cm.0.53-0.56 cm and 0.19-0.22 cm in three directions.②The direction of GTV motion：No motion was noticed in 8.2％.while 73.3％to the right side and 18.5％to the left side in the left-right direction when IBH were compared with EBH.100％were moved to caudal in the the cranial and caudal direction(0.54±0.17)cm].In the anterior-posterior direction,no motion was noticed in 8.2％,while 16.6％to the posterior and 75.2％to the anterior when IBH were compared with EBH.③The GTV motion was correlated with the vafiance of 1ung volumes in IBH-EBH(r=0.683,P=0.032)and not with GTV volume and length.Conclusions Respiration can induce target volume motion in 3 DCRT for mid-thoracic esophageal carcinoma.Compared to EBH.the GTV tends to move to the caudal,the anterior and the ight side in IBH.
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| 关 键 词： | 食管胸中段癌 三维适形放疗 呼吸运动 靶区移位 |
Evaluation of respiration-induced target volume motion in three-dimensional conformal radiotherapy(3D-CRT)for mid-thoracic esophageal carcinoma |
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| HUO Jun-jie,QIAO Xue-ying,CAO Yan-kun,ZHOU Zhi-guo,SONG Yu-zhi,CHI Zi-feng,LIU Xin,WANG Jing.Evaluation of respiration-induced target volume motion in three-dimensional conformal radiotherapy(3D-CRT)for mid-thoracic esophageal carcinoma[J].Chinese Journal of Radiological Medicine and Protection,2009,30(6):295-298. |
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| Authors: | HUO Jun-jie QIAO Xue-ying CAO Yan-kun ZHOU Zhi-guo SONG Yu-zhi CHI Zi-feng LIU Xin WANG Jing |
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| Abstract: | |
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| Keywords: | Mid-thoracic esophageal carcinoma3D-conformal radiotherapyRespiratory movementTarget volume motion |
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