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深部良性纤维组织细胞瘤一例
引用本文:李思彤,吴亚桐,王英,白彦萍.深部良性纤维组织细胞瘤一例[J].中国麻风皮肤病杂志,2021,37(7):454-455.
作者姓名:李思彤  吴亚桐  王英  白彦萍
作者单位:1北京协和医学院研究生院中日友好临床医学研究所,北京,100029;2中日友好医院皮肤性病科,北京,100029
摘    要:深部“良性”纤维组织细胞瘤是一种罕见的纤维组织细胞肿瘤,好发于四肢,本文报道1例。患者,女,56岁,左前臂无痛性皮下肿物4年,组织病理示境界清楚的单发性圆形皮下肿物,约1.8 cm×1.3 cm×0.6 cm,周围有纤维性假包膜,肿瘤细胞丰富,呈梭形或类圆形,编织状致密排列,细胞无明显异型性。 免疫组化:CD34(+), αSMA(部分+), Desmin(-), Stat6(-),KP-1(-),Ki-67(2%+)。诊断:深部良性纤维组织细胞瘤。治疗:手术完整切除肿瘤。随访16个月未见复发。


Deep ‘benign’ fibrous histiocytoma: a case report
LI Sitong,WU Yatong,WANG Ying,BAI Yanping.Deep ‘benign’ fibrous histiocytoma: a case report[J].China Journal of Leprosy and Skin Diseases,2021,37(7):454-455.
Authors:LI Sitong  WU Yatong  WANG Ying  BAI Yanping
Affiliation:1 Department of Dermatology, China-Japan Friendship Hospital, Beijing 100029, China;  2 Clinical Institute of China-Japan Friendship Hospital, Peking Union Medical College Graduate School, Beijing 100029, China
Abstract:Deep “benign” fibrous histiocytoma(DBFH)is a rare benign fibrous tumour which most commonly arise in subcutaneous tissue. We report a 56-year-old female who presented with a painless nodule on her left arm for 4 years. Histopathology examination showed a solitary oval and well-defined borders subcutaneous tumour with fibrous pseudocapsule. The dimensions of tumour were about 1.8 cm×1.3 cm×0.6 cm, composed of bland ovoid to spindle cells arranged in a storiform pattern and with no atypia. Immunohistochemistry demonstrated CD34 positive, αSMA partially positive, and non-expression for Desmin, Stat6 and KP-1. Ki-67 presented a level of proliferation index of about 2%. The diagnosis of DBFH was made and the nodule was completely excised with no recurrence for 16 months.
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