泊洛沙姆在创伤敷料中的应用进展

doi:10.13591/j.cnki.kqyx.2022.02.016

摘要/Abstract

摘要： 颌面部皮肤因处于暴露部位而易产生伤口创面,敷料作为一种促进创伤愈合的优良方式,近年来受到广泛应用。泊洛沙姆因其良好的两亲性、双响应性和生物相容性等在人工合成敷料中极具优势,常被用于载药及缓释系统或作为非离子表面活性剂与其他敷料复合改性。本文通过广泛查阅近年来泊洛沙姆的相关应用文献,就泊洛沙姆在医用敷料领域中的具体应用类型进行归纳总结,包括水凝胶型、纤维型、薄膜型和海绵型等,以期能为临床创伤治疗提供更全面的参考。

关键词: 医用敷料, 创伤愈合, 泊洛沙姆, 普朗尼克

Abstract: The maxillofacial skin is prone to wounds due to exposure, and as an excellent way of promoting wound healing, dressing has been widely used in recent years. Poloxamer has a great advantage in synthetic dressing due to its good amphiphilicity, dual-responsivity, and biocompatibility, which is often used in drug loading and drug delivery systems, or as a nonionicsurfactant to modify other dressings. In this paper, the specific application types of poloxamer medical dressing, including hydrogels, fibers, membranes and sponges, are summarized based on the review of relevant literature on application of poloxamer in recent years, hoping to provide a more comprehensive reference for clinical wound treatment.

Key words: medical dressing, wound healing, poloxamer, pluronic

中图分类号:

R318.08

翟建佳, 刘志辉. 泊洛沙姆在创伤敷料中的应用进展[J]. 口腔医学, 2022, 42(2): 176-179.

ZHAI Jianjia, LIU Zhihui. Application progress of poloxamer in wound dressing[J]. Stomatology, 2022, 42(2): 176-179.

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