The compound of 4,6-bis-(5-amino-3-nitro-1,2,4-triazol-1-yl)-5-nitro pyrimidine(DANTNP) was obtained by the nucleophilic reaction in ethanol using 5-amino-3-nitro-1,2,4-triazole(ANTA) and 4,6-dichlor-5-nitro-pyrimidine(DCNP) as materials,and the structure of DANTNP was confirmed by infrared spectrum (IR), nuclear magnetic resonance (NMR), mass spectrum (MS) and elementrany analysis (EI). The reaction conditions were optimized as: t=6 h,n_CH3ONa:n_ANTA:n_DCNP=2.64:2.4：1,n_ANTA：n_{18-crown-6-ether}=161,the yield of DANTNP is 68%. When adding 18-crown-6-ether,the yield of DANTNP reaches to 84%.