Abstract:Objective: To study on the effect of rice-washed water bleaching products,fried products with bran and raw products of Atractylodis Rhizoma on spleen deficiency rats,and investigate their dryness nature,so as to provide scientific data for clinical medication of Atractylodis Rhizoma. Method: Model of spleen deficiency in rats was prepared by complex method of exogenous dampness disturbing spleen,improper diet and overstrain.SD rats were randomly divided into five groups,8 rats in each group,including the blank group,model group,rice-washed water bleaching Atractylodis Rhizoma group,Atractylodis Rhizoma fried with bran group,crude Atractylodis Rhizoma group.Notes about daily weight,water intake and urine volume were recorded daily.After treatment with 12 days,the gastric emptying velocity and intestinal propulsive ratio were measured by charcoal gavage and spleen index was measured,contents of serum amylase(AMS),D-xylose and gastrin(GAS) were determined. Result: Compared with the model group,each drug treatment group showed weight recovery trend.Fluid consumption in each drug group was higher than that in the model group,and the order was crude Atractylodis Rhizoma group >Atractylodis Rhizoma fried with bran group >rice-washed water bleaching Atractylodis Rhizoma group.The spleen index in each drug group was significantly higher than that in the model group,and Atractylodis Rhizoma fried with bran group and rice-washed water bleaching Atractylodis Rhizoma group were significantly higher than the blank group.Levels of AMS,D-xylose and GAS in each drug group were significantly higher than those in the model group,and Atractylodis Rhizoma fried with bran group and rice-washed water bleaching Atractylodis Rhizoma group were significantly higher than the blank group. Conclusion: Processed products of Atractylodis Rhizoma all have a certain effect on spleen deficiency rats,effects of rice-washed water bleaching products and fried products with bran are significantly better than that of raw products,they all have a good effect of strengthening the spleen and stomach,regulating gastrointestinal function and secretion.Dryness nature is in the order of rice-washed water bleaching products< fried products with bran< raw products.