Industry is the main battlefield of regional green manufacturing. To scientifically evaluate the level of regional industrial green manufacturing is of far-reaching significance for promoting industrial transformation and upgrading and enhancing industrial international competitiveness. This paper defines the connotation of green manufacturing and establishes the evaluation index system of regional industrial green manufacturing level, which covers four aspects: green production, green emission, green science and technology and green quality effect. An Empirical Study on 30 regional industries was carried out by using the method of entropy weight and TOPSIS based on the data of 2017. The study found that the important factors affecting the level of green manufacturing are green products, SO2, green manufacturing invention patents, coal consumption and green manufacturing technology awards. The results show that the overall level of green manufacturing in China is general, and the "high" areas are only Beijing and Guangdong; the "high" areas are only Shandong and Shanghai; the four areas such as Anhui are "general"; the other 22 areas are "low" and "very low"; the eastern region is superior to the central and western regions. Finally, combined with the important influencing factors, some suggestions are put forward to enhance the green manufacturing level of regional industry.