关键词: 非编码RNA, hfq, 靶mRNA

Abstract: Non-coding RNAs (ncRNAs) have been recognized as important regulators, whose function is as co-ordinators of adaptation progresses in response to environmental changes. In bacteria, ncRNAs play important roles to regulate diverse processes including sugar metabolism, envelope stress response quorum sensing and virulence. The regulation model has been an important “branch” of bacterial regulatory networks. This paper reviewed research progress on ncRNAs in recent years, and described in detail the synthesis of bacterial ncRNAs and regulatory mechanism. Due to the unique structure of ncRNAs and complexity of regulatory network, the function research of ncRNAs has become one of the hot points in recent year.

Key words: non-coding RNA, hfq, target mRNA