苏木化学成分及药理作用的研究进展
投稿时间:2019-08-02     点此下载全文
引用本文:邓成杰,刘爽,徐晓云,任亚男,周学刚,魏东华,辛萍,孙世芹.苏木化学成分及药理作用的研究进展[J].中国现代中药,2020,22(5):810-826
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作者中文名作者英文名单位中文名单位英文名E-Mail
邓成杰 DENG Cheng-jie 哈尔滨医科大学(大庆) 药学院,黑龙江大庆163319 College of Pharmacy,Harbin Medical University (Daqing),Daqing 163319,China  
刘爽 LIU Shuang 哈尔滨医科大学(大庆) 药学院,黑龙江大庆163319 College of Pharmacy,Harbin Medical University (Daqing),Daqing 163319,China  
徐晓云 XU Xiao-yun 哈尔滨医科大学(大庆) 药学院,黑龙江大庆163319 College of Pharmacy,Harbin Medical University (Daqing),Daqing 163319,China  
任亚男 REN Ya-nan 佳木斯大学 基础医学院,黑龙江佳木斯154000 Jiamusi University,Jiamusi 154000,China  
周学刚 ZHOU Xue-gang 哈尔滨医科大学(大庆) 药学院,黑龙江大庆163319 College of Pharmacy,Harbin Medical University (Daqing),Daqing 163319,China  
魏东华 WEI Dong-hua 哈尔滨医科大学(大庆) 药学院,黑龙江大庆163319 College of Pharmacy,Harbin Medical University (Daqing),Daqing 163319,China  
辛萍 XIN Ping 哈尔滨医科大学(大庆) 药学院,黑龙江大庆163319 College of Pharmacy,Harbin Medical University (Daqing),Daqing 163319,China  
孙世芹 SUN Shi-qin 哈尔滨医科大学(大庆) 药学院,黑龙江大庆163319 College of Pharmacy,Harbin Medical University (Daqing),Daqing 163319,China 孙世芹,教授,研究方向:苏木抗RA药效物质作用机制及新药研发;E-mail:ssq7610@126.com 
基金项目:哈尔滨医科大学大庆校区导师基金(DSJJ2017001);黑龙江省自然科学基金优秀青年项目(YQ2019H005)
中文摘要:苏木为传统中药,具有活血祛瘀和消肿止痛的功效,临床应用广泛。目前,从苏木心材中共分离鉴定约120个化合物,其主要化学成分包括原苏木素、巴西苏木素、高异黄酮、苏木查尔酮和二苯等类化学成分,具有较强的抗炎、抗肿瘤、免疫抑制、抗菌和血管舒张等药理活性。本文系统性归纳了苏木的化学成分及药理作用的研究进展,以期为苏木的进一步研究开发提供有益参考。
中文关键词:苏木  化学成分  药理作用  抗炎作用
 
Research Progress on Chemical Constituents and Pharmacological Effects of Sappan lignum
Abstract:Sappan lignum is a traditional Chinese medicine with the effect of promoting blood circulation,reducing swelling and relieving pain.It is widely used in clinical practice.At present,about 120 kinds of compounds have been isolated and identified by the heartwood of S.lignum,and their main chemical components include original hematoxylin,brazilin,homoisoflavones,hematoxynes and diphenyls,which have strong anti-inflammatory and anti-inflammatory properties.Pharmacological activities such as anti-tumor,immunosuppression,antibacterial and vasodilation activities.Therefore,this paper systematically summarizes the research progress of the chemical constituents and pharmacological effects of S.lignum to provide some useful references for further research and development of S.lignum.
keywords:Sappan lignum  chemical composition  pharmacological action  anti-inflammatory effect
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